I am interested in solving computational problems currently limiting our ability to resolve and understand brain network activity.
My most recent work has focused on new signal processing methods for functional MRI data that enable improved modeling and removal of motion artifacts. As a result of this work, I have developed, and run, a software initiative at the university (the fMRI Signal Processing Toolbox - SPT) to enable researchers in the field to implement these methods on their own data. This incorporates the BrainWavelet Toolbox which I have developed for denoising non-stationary artefacts from biological time series (Patel et al., 2014, 2015. NeuroImage) which is available free for download from www.brainwavelet.org.
Magnetic resonance imaging (MRI)
No collaborators listed
Associated News Items
Jao T, Schröter M, Chen CL, Cheng YF, Lo CZ, Chou KH, Patel AX, Lin WC, Lin CP, Bullmore ET (2015), “Functional brain network changes associated with clinical and biochemical measures of the severity of hepatic encephalopathy.” Neuroimage 122:332-344 Details
Patel AX, Bullmore ET (2015), “A wavelet-based estimator of the degrees of freedom in denoised fMRI time series for probabilistic testing of functional connectivity and brain graphs.” Neuroimage Details
Patel AX, Burdakov D (2015), “Mechanisms of gain control by voltage-gated channels in intrinsically-firing neurons.” PLoS One 10(3):e0115431 Details
Peeters SC, van de Ven V, Gronenschild EH, Patel AX, Habets P, Goebel R, van Os J, Marcelis M, Genetic Risk and Outcome of Psychosis (G.R.O.U.P.) (2015), “Default mode network connectivity as a function of familial and environmental risk for psychotic disorder.” PLoS One 10(3):e0120030 Details
Patel AX, Kundu P, Rubinov M, Simon Jones P, Vértes PE, Ersche KD, Suckling J, Bullmore ET (2014), “A wavelet method for modeling and despiking motion artifacts from resting-state fMRI time series.” Neuroimage Details
Patel AX, Miller SR, Nathan PJ, Kanakaraj P, Napolitano A, Lawrence P, Koch A, Bullmore ET (2014), “Neuroendocrine and sympathetic responses to an orexin receptor antagonist, SB-649868, and Alprazolam following insulin-induced hypoglycemia in humans.” Psychopharmacology (Berl) Details
Breckel TP, Thiel CM, Bullmore ET, Zalesky A, Patel AX, Giessing C (2013), “Long-term effects of attentional performance on functional brain network topology.” PLoS One 8(9):e74125 Details
Crossley NA, Mechelli A, Vértes PE, Winton-Brown TT, Patel AX, Ginestet CE, McGuire P, Bullmore ET (2013), “Cognitive relevance of the community structure of the human brain functional coactivation network.” Proc Natl Acad Sci U S A 110(28):11583-8 Details
Giessing C, Thiel CM, Alexander-Bloch AF, Patel AX, Bullmore ET (2013), “Human brain functional network changes associated with enhanced and impaired attentional task performance.” J Neurosci 33(14):5903-14 Details
Patel AX, Murphy N, Burdakov D (2012), “Tuning low-voltage-activated A-current for silent gain modulation.” Neural Comput 24(12):3181-90 Details