Dr Alekhya Mandali

University position

Research Associate

Departments

Department of Psychiatry

Research Themes

Systems and Computational Neuroscience

Cognitive and Behavioural Neuroscience

Interests

I am engineer turned computational neuroscientist with a research focus on building mathematical models and applying computational techniques to study the pathophysiology of various neurological and psychiatric conditions such as Parkinson's disease, OCD and addiction. Specifically to understand the effect of various therapeutic techniques such as pharmaceutical medications and deep brain stimulation

During my PhD, I have built spiking network models and studied the effect of dopaminergic medication and subthalamic nucleus(STN) stimulation on cognitive functions of Parkinson's disease

At Dr.Voon's lab, I work on integrating the experimental and computational methodologies for a better understanding of compulsive and impulsive behaviours in OCD and addiction. I am also interested in studying the computational role of STN in decision making in health and disease conditions

Research Focus

Keywords

Computational Neuroscience

reinforcement learning

Parkinson's disease

spiking neuron models

compulsivity and impulsivity

Clinical conditions

Bipolar disorder

Cognitive impairment

Movement disorders

Obsessive compulsive disorder

Parkinson's disease

Equipment

Behavioural analysis

Computational modelling

Collaborators

No collaborators listed

Associated News Items


    Key publications

    Mandali A, Rengaswamy M, Chakravarthy VS, Moustafa AA. (2015), “A spiking Basal Ganglia model of synchrony, exploration and decision making. ” Frontiers in Neuroscience. 9:191.