Mr Angelos Kolias

Angelos Kolias

University position

Clinical Lecturer

Mr Angelos Kolias is pleased to consider applications from prospective PhD students.

Departments

Department of Clinical Neurosciences

Institutes

Neurosurgery Unit

Home page

http://www.rescueasdh.org/

Research Theme

Clinical and Veterinary Neuroscience

Interests

I am a Clinical Lecturer in Neurosurgery.

My research aims to evaluate the clinical effectiveness and understand the mechanisms of action of interventions for traumatic brain injury (TBI).

1. Acute TBI

1.1. Traumatic intracranial hypertension

I was the research fellow of the RESCUEicp trial. My PhD focused on decompressive craniectomy (DC) for traumatic intracranial hypertension.

1.2 Acute subdural haematomas (ASDH)

I am the Co-CI of the RESCUE-ASDH trial (rescueasdh.org) of primary DC for ASDH.

2. Subacute and chronic TBI (chronic subdural haematomas; CSDH)

2.1 Core outcomes

This project aims to develop a ‘core outcome set’, which represents the minimum that should be reported in clinical trials of CSDH.

2.2 Steroids – Dex-CSDH trial

I am the Co-CI of the Dex-CSDH trial of dexamethasone for CSDH (dexcsdh.org).

2.3 Minimally invasive surgery

This project would be suitable for a PhD student interested in evaluating new minimally invasive surgical techniques.

Research Focus

Keywords

Neurotrauma

Decompressive craniectomy

Intracranial hypertension

Subdural haematoma

Multimodal neuro-monitoring

Clinical conditions

Acute subdural haematomas

Cerebrovascular disorders

Chronic subdural haematomas

Spinal trauma

Stroke

Subarachnoid haemorrhage

Traumatic brain injury

Equipment

Computerised tomography

Multimodal neuro-monitoring

Randomised control trials

Collaborators

Cambridge

Marek Czosnyka

Peter Hutchinson

Peter Smielewski

Michael Sutcliffe

United Kingdom

IDEAL Collaboration Web: http://www.ideal-collaboration.net/

Associated News Items


Key publications

Chari A, Hocking KC, Broughton E, Turner C, Santarius T, Hutchinson PJ, Kolias AG (2016), “Core Outcomes and Common Data Elements in Chronic Subdural Hematoma: A Systematic Review of the Literature Focusing on Reported Outcomes.” J Neurotrauma 3(13):1212-9

Hutchinson PJ, Kolias AG, Menon DK (2016), “Craniectomy for Traumatic Intracranial Hypertension” N Engl J Med 375(24):2403-4

Hutchinson PJ, Kolias AG, Timofeev IS, Corteen EA, Czosnyka M, Timothy J, Anderson I, Bulters DO, Belli A, Eynon CA, Wadley J, Mendelow AD, Mitchell PM, Wilson MH, Critchley G, Sahuquillo J, Unterberg A, Servadei F, Teasdale GM, Pickard JD, Menon DK, Murray GD, Kirkpatrick PJ; RESCUEicp Trial Collaborators. (2016), “Trial of Decompressive Craniectomy for Traumatic Intracranial Hypertension.” N Engl J Med 375(12):1119-30

Kolias AG, Chari A, Santarius T, Hutchinson PJ (2014), “Chronic subdural haematoma: modern management and emerging therapies” Nat Rev Neurol 10(10):570-8

Hutchinson PJ, Kolias AG, Czosnyka M, Kirkpatrick PJ, Pickard JD, Menon DK (2013), “Intracranial pressure monitoring in severe traumatic brain injury.” BMJ 346:f1000 Details

Kolias AG, Kirkpatrick PJ, Hutchinson PJ (2013), “Decompressive craniectomy: past, present and future” Nat Rev Neurol 9(7):405-15

Publications

2017

Kolias AG, Hutchinson PJ, Santarius T (2017), “Chronic subdural haematoma: disseminating and implementing best practice” Acta Neurochir (Wien)

2016

Brennan PM, Kolias AG, Joannides AJ, Shapey J, Marcus HJ, Gregson BA, Grover PJ, Hutchinson PJ, Coulter IC; on behalf of the British Neurosurgical Trainee Research Collaborative (2016), “The management and outcome for patients with chronic subdural hematoma: a prospective, multicenter, observational cohort study in the United Kingdom.” J Neurosurg

Fletcher TL, Wirthl B, Kolias AG, Adams H, Hutchinson PJ, Sutcliffe MP (2016), “Modelling of Brain Deformation After Decompressive Craniectomy.” Ann Biomed Eng 44(12):3495-3509

Fountain DM, Kolias AG, Lecky FE, Bouamra O, Lawrence T, Adams H, Bond SJ, Hutchinson PJ (2016), “Survival Trends After Surgery for Acute Subdural Hematoma in Adults Over a 20-year Period” Ann Surg

Jamjoom AA, Phan PN, Hutchinson PJ, Kolias AG. (2016), “Surgical trainee research collaboratives in the UK: an observational study of research activity and publication productivity” BMJ Open 6(2):e010374

Kolias AG, Adams H, Timofeev I, Czosnyka M, Corteen EA, Pickard JD, Turner C, Gregson BA, Kirkpatrick PJ, Murray GD, Menon DK, Hutchinson PJ. (2016), “Decompressive craniectomy following traumatic brain injury: developing the evidence base” Br J Neurosurg 30(2):246-50

Nepogodiev D, Agha R, Chari A, Kolias AG, Rasul F, Kasivisvanathan V, Burdett C, Brady R, Bath M, Chapman SJ, Nepogodiev D, Drake TM, Fitzgerald J, Glasbey J, Harrison EM, Mohan M, Fergusson SJ, Godfrey JJ, Gwozdz AM, Haddow JB, Kaptanis S, Lewis TL, Lin DJ, Miller GW, Sagmeister ML, Symons NR, Harji D, Skerritt C, Gardiner MD, Nicholson G, O'Neill S, Blencowe NS, McNair AG, Dimitriadis PA, Lee M, Wild J, Borakati A, Burke JR, Deekonda P, Kamarajah SK, Mclean KA, Woin E, Stather P, Shalhoub J, Harries RL, Atif M, Bartlett DC, Beggs A, Bhangu A, Lal N, Naumann DN, Ward ST, Shaikh S, Tahir W, Taylor G, National Surgical Research Collaborative. (2016), “UK surgical trainees will continue to support European research collaboration.” Lancet ;388(10043):459-60

2015

Varsos GV, Budohoski KP, Czosnyka M, Kolias AG, Nasr N, Donnelly J, Liu X, Kim DJ, Hutchinson PJ, Kirkpatrick PJ, Varsos VG, Smielewski P (2015), “Cerebral vasospasm affects arterial critical closing pressure” J Cereb Blood Flow Metab 35(2):285-91

2014

Chari A, Kolias AG, Santarius T, Bond S, Hutchinson PJ (2014), “Twist-drill craniostomy with hollow screws for evacuation of chronic subdural hematoma.” J Neurosurg 121(1):176-83 Details

Dyson EW, Kolias AG, Burnstein RM, Hutchinson PJ, Garnett MR, Menon DK, Trivedi RA (2014), “Neuro-critical care: A valuable placement during foundation and early neurosurgical training.” Br J Neurosurg Details

Fletcher TL, Kolias AG, Hutchinson PJ, Sutcliffe MP (2014), “Development of a finite element model of decompressive craniectomy.” PLoS One 9(7):e102131 Details

Fletcher TL, Kolias AG, Hutchinson PJ, Sutcliffe MP. (2014), “A new improved method for assessing brain deformation after decompressive craniectomy” PLoS One ;9(10):e110408

Kolias AG, Coulter IC, Marcus HJ, Gray WP, Brennan PM, Hutchinson PJ, British Neurosurgical Trainee Research Collaborative (2014), “Chronic subdural haematoma: How can we improve patient care and outcomes?” Br J Neurosurg 28(1):136-7 Details

Kolias AG, Hutchinson PJ, Menon DK, Manley GT, Gallagher CN, Servadei F (2014), “Decompressive craniectomy for acute subdural hematomas.” J Neurosurg 120(5):1247-9; author reply 1249 Details

Piercy J, Kolias AG, Hutchinson PJ (2014), “Just what is going on in his head: a patient's journey after a severe traumatic brain injury.” Pract Neurol 14(3):198-200 Details

Stocchetti N, Picetti E, Berardino M, Buki A, Chesnut RM, Fountas KN, Horn P, Hutchinson PJ, Iaccarino C, Kolias AG, Koskinen LO, Latronico N, Maas AI, Payen JF, Rosenthal G, Sahuquillo J, Signoretti S, Soustiel JF, Servadei F (2014), “Clinical applications of intracranial pressure monitoring in traumatic brain injury : Report of the Milan consensus conference.” Acta Neurochir (Wien) 156(8):1615-22 Details

Varsos GV, Budohoski KP, Kolias AG, Liu X, Smielewski P, Varsos VG, Hutchinson PJ, Pickard JD, Czosnyka M (2014), “Relationship of Vascular Wall Tension and Autoregulation Following Traumatic Brain Injury.” Neurocrit Care Details

Wilson MH, Kolias AG, Hutchinson PJ (2014), “Neurotrauma - a multidisciplinary disease.” Int J Clin Pract 68(1):5-7 Details

2013

Allinson KS, Kolias AG, Philippou Y, Bulters DO, Fisher C, Perry A, Dean AF (2013), “A 73 year-old man with a mass at the foramen magnum.” Brain Pathol 23(6):699-702 Details

Bhangu A, Kolias AG, Pinkney T, Hall NJ, Fitzgerald JE (2013), “Surgical research collaboratives in the UK.” Lancet 382(9898):1091-2 Details

Clark DJ, Kolias AG, Corteen EA, Ingham SC, Piercy J, Crick SJ, Menon DK, Hutchinson PJ, RESCUE-ASDH Collaborative Group (2013), “Community consultation in emergency neurotrauma research: results from a pre-protocol survey.” Acta Neurochir (Wien) 155(7):1329-34 Details

Coulter IC, Kolias AG, Marcus HJ, Ahmed AI, Alli S, Al-Mahfoudh R, Borg A, Cowie CJ, Hill CS, Joannides AJ, Jones TL, Kailaya-Vasan A, Livermore JL, Narayanamurthy H, Ngoga D, Shapey J, Tarnaris A, Gregson BA, Gray WP, Nelson RJ, Hutchinson PJ, Brennan PM, UK Neurosurgical Research Network, British Neurosurgical Trainee Research Collaborative (2013), “Proposal for a prospective multi-centre audit of chronic subdural haematoma management in the United Kingdom and Ireland.” Br J Neurosurg Details

Kolias AG, Bulters DO, Cowie CJ, Wilson MH, Afshari FT, Helmy A, Broughton E, Joannides AJ, Zebian B, Harrisson SE, Hill CS, Ahmed AI, Barone DG, Thakur B, McMahon CJ, Adlam DM, Bentley RP, Tolias CM, Mitchell PM, Whitfield PC, Critchley GR, Belli A, Brennan PM, Hutchinson PJ, British Neurosurgical Trainee Research Collaborative, British Neurotrauma Group, UKCRR Collaborative Group (2013), “Proposal for establishment of the UK Cranial Reconstruction Registry (UKCRR).” Br J Neurosurg Details

Kolias AG, Cowie CJ, Tarnaris A, Hutchinson PJ, Brennan PM, British Neurosurgical Trainee Research Collaborative (2013), “Ensuring a bright future for clinical research in surgery with trainee led research networks.” BMJ 347:f5225 Details

Kolias AG, Guilfoyle MR, Helmy A, Allanson J, Hutchinson PJ (2013), “Traumatic brain injury in adults.” Pract Neurol Details

Kolias AG, Jones TL, Cowie CJ, Coulter IC, Afshari FT, Tarnaris A, Nelson RJ, Gray WP, Hutchinson PJ, Brennan PM (2013), “A report from the inaugural meeting of the British Neurosurgical Trainee Research Collaborative held in the Royal College of Surgeons of England, 19 October 2012.” Br J Neurosurg Details

Kolias AG, Scotton WJ, Belli A, King AT, Brennan PM, Bulters DO, Eljamel MS, Wilson MH, Papadopoulos MC, Mendelow AD, Menon DK, Hutchinson PJ (2013), “Surgical management of acute subdural haematomas: current practice patterns in the United Kingdom and the Republic of Ireland.” Br J Neurosurg Details

Kolias AG, Trivedi RA (2013), “Enhancing the exposure of medical students to neurosurgery.” Br J Neurosurg 27(5):706 Details

Scotton WJ, Kolias AG, Ban VS, Crick SJ, Sinha R, Gardner A, Massey K, Minett T, Santarius T, Hutchinson PJ (2013), “Community consultation in emergency neurosurgical research: lessons from a proposed trial for patients with chronic subdural haematomas.” Br J Neurosurg Details

2012

Alam M, Kolias AG, Mannion RJ (2012), “Coronal computed tomography of the upper cervical spine.” BMJ 345:e6811 Details

Alam M, Kolias AG, Trivedi RA (2012), “Magnetic resonance imaging of lumbar spine.” BMJ 344:e4010 Details

Aries MJ, Czosnyka M, Budohoski KP, Kolias AG, Radolovich DK, Lavinio A, Pickard JD, Smielewski P (2012), “Continuous Monitoring of Cerebrovascular Reactivity Using Pulse Waveform of Intracranial Pressure.” Neurocrit Care Details

Aries MJ, Czosnyka M, Budohoski KP, Steiner LA, Lavinio A, Kolias AG, Hutchinson PJ, Brady KM, Menon DK, Pickard JD, Smielewski P (2012), “Continuous determination of optimal cerebral perfusion pressure in traumatic brain injury.” Crit Care Med Details

Kolias AG, Belli A, Li LM, Timofeev I, Corteen EA, Santarius T, Menon DK, Pickard JD, Kirkpatrick PJ, Hutchinson PJ (2012), “Primary decompressive craniectomy for acute subdural haematomas: results of an international survey.” Acta Neurochir (Wien) Details

Kolias AG, Cowie CJ, Tarnaris A, Hutchinson PJ, Brennan PM (2012), “Proposal for a British neurosurgical trainee research collaborative.” Br J Neurosurg Details

Kolias AG, Li LM, Corteen EA, Timofeev I, Kirkpatrick PJ, Hutchinson PJ (2012), “Decompressive craniectomy versus craniotomy for head-injured patients with acute subdural hematoma.” J Trauma Acute Care Surg 72(5):1451 Details

Kolias AG, Li LM, Guilfoyle MR, Timofeev I, Corteen EA, Pickard JD, Kirkpatrick PJ, Menon DK, Hutchinson PJ (2012), “Decompressive craniectomy for acute subdural hematomas: time for a randomized trial.” Acta Neurochir (Wien) Details

Kolias AG, Sinha R, Park H, Santarius T, Hutchinson PJ (2012), “Surgical management of chronic subdural hematomas: in need of better evidence.” Acta Neurochir (Wien) Details

Li LM, Kolias AG, Guilfoyle MR, Timofeev I, Corteen EA, Pickard JD, Menon DK, Kirkpatrick PJ, Hutchinson PJ (2012), “Outcome following evacuation of acute subdural haematomas: a comparison of craniotomy with decompressive craniectomy.” Acta Neurochir (Wien) 154(9):1555-61 Details

Timofeev I, Santarius T, Kolias AG, Hutchinson PJ (2012), “Decompressive craniectomy - operative technique and perioperative care.” Adv Tech Stand Neurosurg 38:115-36 Details

2011

Hutchinson PJ, Timofeev I, Kolias AG, Corteen EA, Czosnyka M, Menon DK, Pickard JD, Kirkpatrick PJ (2011), “Decompressive craniectomy for traumatic brain injury: The jury is still out.” Br J Neurosurg 25(3):441-2 Details

2010

Kolias AG, Derham C, Mankad K, Hasegawa H, O'Kane R, Ismail A, Phillips NI (2010), “Multiple cranial neuropathy as the initial presentation of metastatic prostate adenocarcinoma: case report and review of literature.” Acta Neurochir (Wien) 152(7):1251-5 Details

Santarius T, Kirkpatrick PJ, Kolias AG, Hutchinson PJ (2010), “Working toward rational and evidence-based treatment of chronic subdural hematoma.” Clin Neurosurg 57:112-22 Details

2009

Kolias AG, Odak S, Tyagi AK (2009), “Cauda equina syndrome. Examination must be thorough.” BMJ 338:b1724 Details

Kolias AG, Pal D, Shivane A, Ismail A, Tyagi AK (2009), “Paediatric intramedullary spinal cord cavernous malformations: case report and review of the literature.” Clin Neurol Neurosurg 111(9):784-8 Details

Kolias AG, Sen J, Belli A (2009), “Pathogenesis of cerebral vasospasm following aneurysmal subarachnoid hemorrhage: putative mechanisms and novel approaches.” J Neurosci Res 87(1):1-11 Details