Dr Alex Whitworth

Alex Whitworth

University position

MRC Programme Leader

Dr Alex Whitworth is pleased to consider applications from prospective PhD students.

Departments

MRC Mitochondrial Biology Unit

Institutes

Mitochondrial Biology Unit, MRC

Home page

http://www.mrc-mbu.cam.ac.uk/people/... (personal home page)

Research Themes

Cellular and Molecular Neuroscience

Developmental Neuroscience

Interests

My lab is interested in understanding the mechanisms of mitochondrial homeostasis in relation to neurodegenerative diseases such as Parkinson's disease and motor neuron disease. We use a combination of the powerful genetic techniques of Drosophila and molecular, cell biology and biochemical approaches in mammalian cells. Insights into these mechanisms will deliver a greater understanding of the role of mitochondrial maintenance in the health and dysfunction of the nervous system in a physiological context and will help guide therapeutic development to combat neurodegenerative diseases.

Research Focus

Keywords

mitochondria

Drosophila

neurodegeneration

parkinson's

motor neuron disease

Clinical conditions

Genetic disorders

Movement disorders

Parkinson's disease

Equipment

Behavioural analysis

Confocal microscopy

Enzyme assays

Fluorescence microscopy

Immunohistochemistry

Microscopy

Protein purification

Collaborators

No collaborators listed

Associated News Items