Professor Adrian Owen

University position
Senior Scientist/Assistant Director
Institutes
MRC Cognition and Brain Sciences Unit
Home page
http://adrianowen.org (personal home page)
Research Themes
Interests
In January 2011, my research team and I moved to the University of Western Ontario, Canada, where I have taken up the Canada Excellence Research Chair (CERC) in Cognitive Neuroscience and Imaging. Although I continue to maintain strong collaborative links with many former colleagues at Cambridge, I am no longer responding to email sent to my Cambridge address or to applications to work with me in Cambridge. For alternative options and updated details about my current research, please visit my personal website at http://adrianowen.org

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Research Focus
KeywordsfMRI consciousness frontal lobe Parkinson's disease imaging |
Clinical conditionsAlzheimer's disease Cognitive impairment Dementia Huntington's disease Locked-in syndrome Minimally conscious state Movement disorders Obsessive compulsive disorder Parkinson's disease Progressive supranuclear palsy Traumatic brain injury Vegetative state |
Equipment
Behavioural analysis
Magnetic resonance imaging (MRI)
Magnetoencephalography (MEG)
Neuropsychological testing
Positron Emission Tomography (PET)
Transcranial magnetic stimulation (TMS)
Collaborators
Cambridge | United KingdomJohn Parkinson Web: http://www.psychology.bangor.ac.uk/~john_p... |
Key publications
Monti MM, Vanhaudenhuyse A, Coleman MR, Boly M, Pickard JD, Tshibanda L, Owen AM, Laureys S (2010), “Willful modulation of brain activity in disorders of consciousness.” N Engl J Med 362(7):579-89 Details
Owen AM, Hampshire A, Grahn JA, Stenton R, Dajani S, Burns AS, Howard RJ, Ballard CG (2010), “Putting brain training to the test.” Nature 465(7299):775-8 Details
Hampshire A, Owen AM (2006), “Fractionating attentional control using event related fMRI” Cerebral Cortex 16(12):1679-1689 Details
Owen AM, Coleman MR, Davis MH, Boly M, Laureys S, Pickard JD (2006), “Detecting awareness in the vegetative state” Science 313:1402 Details
Publications
2012
Cruse D, Chennu S, Chatelle C, Fernández-Espejo D, Bekinschtein TA, Pickard JD, Laureys S, Owen AM (2012), “Relationship between etiology and covert cognition in the minimally conscious state.” Neurology 78(11):816-22 Details
Fallon SJ, Williams-Gray CH, Barker RA, Owen AM, Hampshire A (2012), “Prefrontal Dopamine Levels Determine the Balance between Cognitive Stability and Flexibility.” Cereb Cortex Details
Hampshire A, Chaudhry AM, Owen AM, Roberts AC (2012), “Dissociable roles for lateral orbitofrontal cortex and lateral prefrontal cortex during preference driven reversal learning.” Neuroimage 59(4):4102-12 Details
Monti MM, Pickard JD, Owen AM (2012), “Visual cognition in disorders of consciousness: From V1 to top-down attention.” Hum Brain Mapp Details
2011
Bekinschtein TA, Davis MH, Rodd JM, Owen AM (2011), “Why clowns taste funny: the relationship between humor and semantic ambiguity.” J Neurosci 31(26):9665-71 Details
Bekinschtein TA, Manes FF, Villarreal M, Owen AM, Della-Maggiore V (2011), “Functional imaging reveals movement preparatory activity in the vegetative state.” Front Hum Neurosci 5:5 Details
Cruse D, Chennu S, Chatelle C, Bekinschtein TA, Fernández-Espejo D, Pickard JD, Laureys S, Owen AM (2011), “Bedside detection of awareness in the vegetative state: a cohort study.” Lancet 378(9809):2088-94 Details
Fernández-Espejo D, Bekinschtein T, Monti MM, Pickard JD, Junque C, Coleman MR, Owen AM (2011), “Diffusion weighted imaging distinguishes the vegetative state from the minimally conscious state.” Neuroimage 54(1):103-12 Details
2010
Cruse D, Owen AM (2010), “Consciousness revealed: new insights into the vegetative and minimally conscious states.” Curr Opin Neurol Details
Hampshire A, Chamberlain SR, Monti MM, Duncan J, Owen AM (2010), “The role of the right inferior frontal gyrus: inhibition and attentional control.” Neuroimage 50(3):1313-9 Details
Hampshire A, Thompson R, Duncan J, Owen AM (2010), “Lateral Prefrontal Cortex Subregions Make Dissociable Contributions during Fluid Reasoning.” Cereb Cortex Details
Hughes LE, Barker RA, Owen AM, Rowe JB (2010), “Parkinson's disease and healthy aging: Independent and interacting effects on action selection.” Hum Brain Mapp Details
Kempton MJ, Ettinger U, Foster R, Williams SC, Calvert GA, Hampshire A, Zelaya FO, O'Gorman RL, McMorris T, Owen AM, Smith MS (2010), “Dehydration affects brain structure and function in healthy adolescents.” Hum Brain Mapp Details
Memon FN, Owen AM, Sanchez-Graillet O, Upton GJ, Harrison AP (2010), “Identifying the impact of G-quadruplexes on Affymetrix 3' arrays using cloud computing.” J Integr Bioinform 7(2):111 Details
Monti MM, Laureys S, Owen AM (2010), “The vegetative state.” BMJ 341:c3765 Details
Piech RM, Lewis J, Parkinson CH, Owen AM, Roberts AC, Downing PE, Parkinson JA (2010), “Neural correlates of affective influence on choice.” Brain Cogn 72(2):282-8 Details
Rowe JB, Hughes LE, Barker RA, Owen AM (2010), “Dynamic causal modelling of effective connectivity from fMRI: Are results reproducible and sensitive to Parkinson's disease and its treatment?” Neuroimage Details
2009
Berry EL, Hampshire A, Rowe J, Hodges S, Kapur N, Watson P, Browne G, Smyth G, Wood K, Owen AM (2009), “The neural basis of effective memory therapy in a patient with limbic encephalitis.” J Neurol Neurosurg Psychiatry Details
Chaudhry AM, Parkinson JA, Hinton EC, Owen AM, Roberts AC (2009), “Preference judgements involve a network of structures within frontal, cingulate and insula cortices.” Eur J Neurosci 29(5):1047-55 Details
Coleman MR, Bekinschtein T, Monti MM, Owen AM, Pickard JD (2009), “A multimodal approach to the assessment of patients with disorders of consciousness.” Prog Brain Res 177:231-48 Details
Coleman MR, Davis MH, Rodd JM, Robson T, Ali A, Owen AM, Pickard JD (2009), “Towards the routine use of brain imaging to aid the clinical diagnosis of disorders of consciousness.” Brain 132(Pt 9):2541-52 Details
Grahn JA, Parkinson JA, Owen AM (2009), “The role of the basal ganglia in learning and memory: neuropsychological studies.” Behav Brain Res 199(1):53-60 Details
Hampshire A, Thompson R, Duncan J, Owen AM (2009), “Selective tuning of the right inferior frontal gyrus during target detection.” Cogn Affect Behav Neurosci 9(1):103-12 Details
Monti MM, Coleman MR, Owen AM (2009), “Neuroimaging and the vegetative state: resolving the behavioral assessment dilemma?” Ann N Y Acad Sci 1157:81-9 Details
Monti MM, Coleman MR, Owen AM (2009), “Executive functions in the absence of behavior: functional imaging of the minimally conscious state.” Prog Brain Res 177:249-60 Details
Owen AM, Schiff ND, Laureys S (2009), “A new era of coma and consciousness science.” Prog Brain Res 177:399-411 Details
Piech RM, Lewis J, Parkinson CH, Owen AM, Roberts AC, Downing PE, Parkinson JA (2009), “Neural correlates of appetite and hunger-related evaluative judgments.” PLoS One 4(8):e6581 Details
2008
Chamberlain SR, Menzies L, Hampshire A, Suckling J, Fineberg NA, del Campo N, Aitken M, Craig K, Owen AM, Bullmore ET, Robbins TW, Sahakian BJ (2008), “Orbitofrontal dysfunction in patients with obsessive-compulsive disorder and their unaffected relatives.” Science 321(5887):421-2 Details
Coleman MR, Owen AM (2008), “Functional neuroimaging of disorders of consciousness.” Int Anesthesiol Clin 46(3):147-57 Details
Dove A, Manly T, Epstein R, Owen AM (2008), “The engagement of mid-ventrolateral prefrontal cortex and posterior brain regions in intentional cognitive activity.” Hum Brain Mapp 29(1):107-19 Details
Grahn JA, Parkinson JA, Owen AM (2008), “The cognitive functions of the caudate nucleus.” Prog Neurobiol 86(3):141-55 Details
Hampshire A, Gruszka A, Fallon SJ, Owen AM (2008), “Inefficiency in self-organized attentional switching in the normal aging population is associated with decreased activity in the ventrolateral prefrontal cortex.” J Cogn Neurosci 20(9):1670-86 Details
Hampshire A, Thompson R, Duncan J, Owen AM (2008), “The target selective neural response--similarity, ambiguity, and learning effects.” PLoS One 3(6):e2520 Details
Owen AM (2008), “Disorders of consciousness.” Ann N Y Acad Sci 1124:225-38 Details
Owen AM, Coleman MR (2008), “Using neuroimaging to detect awareness in disorders of consciousness.” Funct Neurol 23(4):189-94 Details
Owen AM, Coleman MR (2008), “Detecting awareness in the vegetative state.” Ann N Y Acad Sci 1129:130-8 Details
Owen AM, Coleman MR (2008), “Functional neuroimaging of the vegetative state.” Nat Rev Neurosci 9(3):235-43 Details
Rowe J, Hughes L, Eckstein D, Owen AM (2008), “Rule-selection and action-selection have a shared neuroanatomical basis in the human prefrontal and parietal cortex.” Cereb Cortex 18(10):2275-85 Details
Rowe JB, Eckstein D, Braver T, Owen AM (2008), “How does reward expectation influence cognition in the human brain?” J Cogn Neurosci 20(11):1980-92 Details
Rowe JB, Hughes L, Ghosh BC, Eckstein D, Williams-Gray CH, Fallon S, Barker RA, Owen AM (2008), “Parkinson's disease and dopaminergic therapy--differential effects on movement, reward and cognition.” Brain 131(Pt 8):2094-105 Details
Rowe JB, Hughes L, Williams-Gray CH, Bishop S, Fallon S, Barker RA, Owen AM (2008), “The val(158)met COMT polymorphism's effect on atrophy in healthy aging and Parkinson's disease.” Neurobiol Aging Details
Williams-Gray CH, Hampshire A, Barker RA, Owen AM (2008), “Attentional control in Parkinson's disease is dependent on COMT val 158 met genotype.” Brain 131(Pt 2):397-408 Details
2007
Boly M, Coleman MR, Davis MH, Hampshire A, Bor D, Moonen G, Maquet PA, Pickard JD, Laureys S, Owen AM (2007), “When thoughts become action: an fMRI paradigm to study volitional brain activity in non-communicative brain injured patients.” Neuroimage 36(3):979-92 Details
Bor D, Owen AM (2007), “Cognitive training: neural correlates of expert skills.” Curr Biol 17(3):R95-7 Details
Bor D, Owen AM (2007), “A common prefrontal-parietal network for mnemonic and mathematical recoding strategies within working memory.” Cereb Cortex 17(4):778-86 Details
Coleman MR, Rodd JM, Davis MH, Johnsrude IS, Menon DK, Pickard JD, Owen AM (2007), “Do vegetative patients retain aspects of language comprehension? Evidence from fMRI.” Brain 130(Pt 10):2494-507 Details
Davis MH, Coleman MR, Absalom AR, Rodd JM, Johnsrude IS, Matta BF, Owen AM, Menon DK (2007), “Dissociating speech perception and comprehension at reduced levels of awareness.” Proc Natl Acad Sci U S A 104(41):16032-7 Details
Hampshire A, Duncan J, Owen AM (2007), “Selective tuning of the blood oxygenation level-dependent response during simple target detection dissociates human frontoparietal subregions.” J Neurosci 27(23):6219-23 Details
Malhi GS, Lagopoulos J, Owen AM, Ivanovski B, Shnier R, Sachdev P (2007), “Reduced activation to implicit affect induction in euthymic bipolar patients: an fMRI study.” J Affect Disord 97(1-3):109-22 Details
Owen AM, Coleman MR (2007), “Functional MRI in disorders of consciousness: advantages and limitations.” Curr Opin Neurol 20(6):632-7 Details
Owen AM, Coleman MR, Boly M, Davis MH, Laureys S, Pickard JD (2007), “Using functional magnetic resonance imaging to detect covert awareness in the vegetative state.” Arch Neurol 64(8):1098-102 Details
Williams-Gray CH, Hampshire A, Robbins TW, Owen AM, Barker RA (2007), “Catechol O-methyltransferase Val158Met genotype influences frontoparietal activity during planning in patients with Parkinson's disease.” J Neurosci 27(18):4832-8 Details
2006
Bor D, Duncan J, Lee AC, Parr A, Owen AM (2006), “Frontal lobe involvement in spatial span: converging studies of normal and impaired function.” Neuropsychologia 44(2):229-37 Details
Bor D, Owen AM (2006), “Working memory: linking capacity with selectivity.” Curr Biol 16(4):R136-8 Details
Christoff K, Owen AM (2006), “Improving reverse neuroimaging inference: cognitive domain versus cognitive complexity.” Trends Cogn Sci 10(8):352-3 Details
Dove A, Brett M, Cusack R, Owen AM (2006), “Dissociable contributions of the mid-ventrolateral frontal cortex and the medial temporal lobe system to human memory.” Neuroimage 31(4):1790-801 Details
Gould RL, Arroyo B, Brown RG, Owen AM, Bullmore ET, Howard RJ (2006), “Brain mechanisms of successful compensation during learning in Alzheimer disease.” Neurology 67(6):1011-7 Details
Gould RL, Brown RG, Owen AM, Bullmore ET, Howard RJ (2006), “Task-induced deactivations during successful paired associates learning: an effect of age but not Alzheimer's disease.” Neuroimage 31(2):818-31 Details
Grahn JA, Owen AM (2006), “Memory: obstacle avoidance without visual cues.” Curr Biol 16(7):R247-9 Details
Hinton EC, Holland AJ, Gellatly MS, Soni S, Owen AM (2006), “An investigation into food preferences and the neural basis of food-related incentive motivation in Prader-Willi syndrome.” J Intellect Disabil Res 50(Pt 9):633-42 Details
Hinton EC, Holland AJ, Gellatly MS, Soni S, Patterson M, Ghatei MA, Owen AM (2006), “Neural representations of hunger and satiety in Prader-Willi syndrome.” Int J Obes (Lond) 30(2):313-21 Details
Hon N, Epstein RA, Owen AM, Duncan J (2006), “Frontoparietal activity with minimal decision and control.” J Neurosci 26(38):9805-9 Details
Laureys S, Giacino JT, Schiff ND, Schabus M, Owen AM (2006), “How should functional imaging of patients with disorders of consciousness contribute to their clinical rehabilitation needs?” Curr Opin Neurol 19(6):520-7 Details
Slabosz A, Lewis SJ, Smigasiewicz K, Szymura B, Barker RA, Owen AM (2006), “The role of learned irrelevance in attentional set-shifting impairments in Parkinson's disease.” Neuropsychology 20(5):578-88 Details
Unterrainer JM, Owen AM (2006), “Planning and problem solving: from neuropsychology to functional neuroimaging.” J Physiol Paris 99(4-6):308-17 Details
2005
Cheesman AL, Barker RA, Lewis SJ, Robbins TW, Owen AM, Brooks DJ (2005), “Lateralisation of striatal function: evidence from 18F-dopa PET in Parkinson's disease.” J Neurol Neurosurg Psychiatry 76(9):1204-10 Details
Gould RL, Brown RG, Owen AM, Bullmore ET, Williams SC, Howard RJ (2005), “Functional neuroanatomy of successful paired associate learning in Alzheimer's disease.” Am J Psychiatry 162(11):2049-60 Details
Lewis SJ, Foltynie T, Blackwell AD, Robbins TW, Owen AM, Barker RA (2005), “Heterogeneity of Parkinson's disease in the early clinical stages using a data driven approach.” J Neurol Neurosurg Psychiatry 76(3):343-8 Details
Lewis SJ, Slabosz A, Robbins TW, Barker RA, Owen AM (2005), “Dopaminergic basis for deficits in working memory but not attentional set-shifting in Parkinson's disease.” Neuropsychologia 43(6):823-32 Details
Owen AM, Coleman MR, Menon DK, Berry EL, Johnsrude IS, Rodd JM, Davis MH, Pickard JD (2005), “Using a hierarchical approach to investigate residual auditory cognition in persistent vegetative state.” Prog Brain Res 150:457-71 Details
Owen AM, Coleman MR, Menon DK, Johnsrude IS, Rodd JM, Davis MH, Taylor K, Pickard JD (2005), “Residual auditory function in persistent vegetative state: a combined PET and fMRI study.” Neuropsychol Rehabil 15(3-4):290-306 Details
Owen AM, McMillan KM, Laird AR, Bullmore E (2005), “N-back working memory paradigm: a meta-analysis of normative functional neuroimaging studies.” Hum Brain Mapp 25(1):46-59 Details
Simons JS, Gilbert SJ, Owen AM, Fletcher PC, Burgess PW (2005), “Distinct roles for lateral and medial anterior prefrontal cortex in contextual recollection.” J Neurophysiol 94(1):813-20 Details
Simons JS, Owen AM, Fletcher PC, Burgess PW (2005), “Anterior prefrontal cortex and the recollection of contextual information.” Neuropsychologia 43(12):1774-83 Details
2004
Bor D, Cumming N, Scott CE, Owen AM (2004), “Prefrontal cortical involvement in verbal encoding strategies.” Eur J Neurosci 19(12):3365-70 Details
Curran E, Sykacek P, Stokes M, Roberts SJ, Penny W, Johnsrude I, Owen AM (2004), “Cognitive tasks for driving a brain-computer interfacing system: a pilot study.” IEEE Trans Neural Syst Rehabil Eng 12(1):48-54 Details
Hinton EC, Parkinson JA, Holland AJ, Arana FS, Roberts AC, Owen AM (2004), “Neural contributions to the motivational control of appetite in humans.” Eur J Neurosci 20(5):1411-8 Details
Laureys S, Owen AM, Schiff ND (2004), “Brain function in coma, vegetative state, and related disorders.” Lancet Neurol 3(9):537-46 Details
Lewis SJ, Dove A, Robbins TW, Barker RA, Owen AM (2004), “Striatal contributions to working memory: a functional magnetic resonance imaging study in humans.” Eur J Neurosci 19(3):755-60 Details
Malhi GS, Lagopoulos J, Owen AM, Yatham LN (2004), “Bipolaroids: functional imaging in bipolar disorder.” Acta Psychiatr Scand Suppl (422):46-54 Details
Ouellet MC, Beauchamp MH, Owen AM, Doyon J (2004), “Acquiring a cognitive skill with a new repeating version of the Tower of London task.” Can J Exp Psychol 58(4):272-88 Details
Owen AM (2004), “Cognitive dysfunction in Parkinson's disease: the role of frontostriatal circuitry.” Neuroscientist 10(6):525-37 Details
Owen AM (2004), “Working memory: imaging the magic number four.” Curr Biol 14(14):R573-4 Details
Ramnani N, Owen AM (2004), “Anterior prefrontal cortex: insights into function from anatomy and neuroimaging.” Nat Rev Neurosci 5(3):184-94 Details
2003
Arana FS, Parkinson JA, Hinton E, Holland AJ, Owen AM, Roberts AC (2003), “Dissociable contributions of the human amygdala and orbitofrontal cortex to incentive motivation and goal selection.” J Neurosci 23(29):9632-8 Details
Bor D, Duncan J, Wiseman RJ, Owen AM (2003), “Encoding strategies dissociate prefrontal activity from working memory demand.” Neuron 37(2):361-7 Details
Gould RL, Brown RG, Owen AM, ffytche DH, Howard RJ (2003), “fMRI BOLD response to increasing task difficulty during successful paired associates learning.” Neuroimage 20(2):1006-19 Details
Lewis SJ, Cools R, Robbins TW, Dove A, Barker RA, Owen AM (2003), “Using executive heterogeneity to explore the nature of working memory deficits in Parkinson's disease.” Neuropsychologia 41(6):645-54 Details
Lewis SJ, Dove A, Robbins TW, Barker RA, Owen AM (2003), “Cognitive impairments in early Parkinson's disease are accompanied by reductions in activity in frontostriatal neural circuitry.” J Neurosci 23(15):6351-6 Details
Manly T, Owen AM, McAvinue L, Datta A, Lewis GH, Scott SK, Rorden C, Pickard J, Robertson IH (2003), “Enhancing the sensitivity of a sustained attention task to frontal damage: convergent clinical and functional imaging evidence.” Neurocase 9(4):340-9 Details
Owen AM (2003), “HERA today, gone tomorrow?” Trends Cogn Sci 7(9):383-384 Details
Tsang WM, Owen AM, Collinson PO, Barth JH (2003), “Surveys on the use of cardiac markers in the UK.” Ann Clin Biochem 40(Pt 2):138-42 Details
2002
Brett M, Johnsrude IS, Owen AM (2002), “The problem of functional localization in the human brain.” Nat Rev Neurosci 3(3):243-9 Details
Calder AJ, Lawrence AD, Keane J, Scott SK, Owen AM, Christoffels I, Young AW (2002), “Reading the mind from eye gaze.” Neuropsychologia 40(8):1129-38 Details
Cools R, Clark L, Owen AM, Robbins TW (2002), “Defining the neural mechanisms of probabilistic reversal learning using event-related functional magnetic resonance imaging.” J Neurosci 22(11):4563-7 Details
Cools R, Stefanova E, Barker RA, Robbins TW, Owen AM (2002), “Dopaminergic modulation of high-level cognition in Parkinson's disease: the role of the prefrontal cortex revealed by PET.” Brain 125(Pt 3):584-94 Details
Cox SM, Stefanova E, Johnsrude IS, Robbins TW, Owen AM (2002), “Preference formation and working memory in Parkinson's disease and normal ageing.” Neuropsychologia 40(3):317-26 Details
Hodgson TL, Tiesman B, Owen AM, Kennard C (2002), “Abnormal gaze strategies during problem solving in Parkinson's disease.” Neuropsychologia 40(4):411-22 Details
Lee AC, Graham KS, Simons JS, Hodges JR, Owen AM, Patterson K (2002), “Regional brain activations differ for semantic features but not categories.” Neuroreport 13(12):1497-501 Details
Lee AC, Robbins TW, Graham KS, Owen AM (2002), “"Pray or Prey?" dissociation of semantic memory retrieval from episodic memory processes using positron emission tomography and a novel homophone task.” Neuroimage 16(3 Pt 1):724-35 Details
Lee AC, Robbins TW, Smith S, Calvert GA, Tracey I, Matthews P, Owen AM (2002), “Evidence for asymmetric frontal-lobe involvement in episodic memory from functional magnetic resonance imaging and patients with unilateral frontal-lobe excisions.” Neuropsychologia 40(13):2420-37 Details
Owen AM, Menon DK, Johnsrude IS, Bor D, Scott SK, Manly T, Williams EJ, Mummery C, Pickard JD (2002), “Detecting residual cognitive function in persistent vegetative state.” Neurocase 8(5):394-403 Details
2001
Bor D, Duncan J, Owen AM (2001), “The role of spatial configuration in tests of working memory explored with functional neuroimaging.” Scand J Psychol 42(3):217-24 Details
Dagher A, Owen AM, Boecker H, Brooks DJ (2001), “The role of the striatum and hippocampus in planning: a PET activation study in Parkinson's disease.” Brain 124(Pt 5):1020-32 Details
Rowe JB, Owen AM, Johnsrude IS, Passingham RE (2001), “Imaging the mental components of a planning task.” Neuropsychologia 39(3):315-27 Details
Simons JS, Graham KS, Owen AM, Patterson K, Hodges JR (2001), “Perceptual and semantic components of memory for objects and faces: a pet study.” J Cogn Neurosci 13(4):430-43 Details
2000
Duncan J, Owen AM (2000), “Common regions of the human frontal lobe recruited by diverse cognitive demands.” Trends Neurosci 23(10):475-83 Details
Hodgson TL, Bajwa A, Owen AM, Kennard C (2000), “The strategic control of gaze direction in the Tower-of-London task.” J Cogn Neurosci 12(5):894-907 Details
Johnsrude IS, Owen AM, White NM, Zhao WV, Bohbot V (2000), “Impaired preference conditioning after anterior temporal lobe resection in humans.” J Neurosci 20(7):2649-56 Details
Lee AC, Robbins TW, Owen AM (2000), “Episodic memory meets working memory in the frontal lobe: functional neuroimaging studies of encoding and retrieval.” Crit Rev Neurobiol 14(3-4):165-97 Details
Lee AC, Robbins TW, Pickard JD, Owen AM (2000), “Asymmetric frontal activation during episodic memory: the effects of stimulus type on encoding and retrieval.” Neuropsychologia 38(5):677-92 Details
Mehta MA, Owen AM, Sahakian BJ, Mavaddat N, Pickard JD, Robbins TW (2000), “Methylphenidate enhances working memory by modulating discrete frontal and parietal lobe regions in the human brain.” J Neurosci 20(6):RC65 Details
Owen AM (2000), “The role of the lateral frontal cortex in mnemonic processing: the contribution of functional neuroimaging.” Exp Brain Res 133(1):33-43 Details
Stern CE, Owen AM, Tracey I, Look RB, Rosen BR, Petrides M (2000), “Activity in ventrolateral and mid-dorsolateral prefrontal cortex during nonspatial visual working memory processing: evidence from functional magnetic resonance imaging.” Neuroimage 11(5 Pt 1):392-9 Details
Vandenberghe R, Duncan J, Arnell KM, Bishop SJ, Herrod NJ, Owen AM, Minhas PS, Dupont P, Pickard JD, Orban GA (2000), “Maintaining and shifting attention within left or right hemifield.” Cereb Cortex 10(7):706-13 Details
1999
Dagher A, Owen AM, Boecker H, Brooks DJ (1999), “Mapping the network for planning: a correlational PET activation study with the Tower of London task.” Brain 122 ( Pt 10):1973-87 Details
Johnsrude IS, Owen AM, Crane J, Milner B, Evans AC (1999), “A cognitive activation study of memory for spatial relationships.” Neuropsychologia 37(7):829-41 Details
Menon DK, Owen AM, Pickard JD (1999), “Response from Menon, Owen and Pickard.” Trends Cogn Sci 3(2):44-46 Details
Owen AM, Doyon J (1999), “The cognitive neuropsychology of Parkinson's disease: a functional neuroimaging perspective.” Adv Neurol 80:49-56 Details
Owen AM, Herrod NJ, Menon DK, Clark JC, Downey SP, Carpenter TA, Minhas PS, Turkheimer FE, Williams EJ, Robbins TW, Sahakian BJ, Petrides M, Pickard JD (1999), “Redefining the functional organization of working memory processes within human lateral prefrontal cortex.” Eur J Neurosci 11(2):567-74 Details
Pantelis C, Barber FZ, Barnes TR, Nelson HE, Owen AM, Robbins TW (1999), “Comparison of set-shifting ability in patients with chronic schizophrenia and frontal lobe damage.” Schizophr Res 37(3):251-70 Details
Rogers RD, Owen AM, Middleton HC, Williams EJ, Pickard JD, Sahakian BJ, Robbins TW (1999), “Choosing between small, likely rewards and large, unlikely rewards activates inferior and orbital prefrontal cortex.” J Neurosci 19(20):9029-38 Details
1998
Menon DK, Owen AM, Williams EJ, Minhas PS, Allen CM, Boniface SJ, Pickard JD (1998), “Cortical processing in persistent vegetative state. Wolfson Brain Imaging Centre Team.” Lancet 352(9123):200 Details
Owen AM (1998), “Memory: dissociating multiple memory processes.” Curr Biol 8(23):R850-2 Details
Owen AM, Doyon J, Dagher A, Sadikot A, Evans AC (1998), “Abnormal basal ganglia outflow in Parkinson's disease identified with PET. Implications for higher cortical functions.” Brain 121 ( Pt 5):949-65 Details
Owen AM, Stern CE, Look RB, Tracey I, Rosen BR, Petrides M (1998), “Functional organization of spatial and nonspatial working memory processing within the human lateral frontal cortex.” Proc Natl Acad Sci U S A 95(13):7721-6 Details
Robbins TW, James M, Owen AM, Sahakian BJ, Lawrence AD, McInnes L, Rabbitt PM (1998), “A study of performance on tests from the CANTAB battery sensitive to frontal lobe dysfunction in a large sample of normal volunteers: implications for theories of executive functioning and cognitive aging.Cambridge Neuropsychological Test Automated Battery.” J Int Neuropsychol Soc 4(5):474-90 Details
1997
Owen AM (1997), “Cognitive planning in humans: neuropsychological, neuroanatomical and neuropharmacological perspectives.” Prog Neurobiol 53(4):431-50 Details
Owen AM (1997), “The functional organization of working memory processes within human lateral frontal cortex: the contribution of functional neuroimaging.” Eur J Neurosci 9(7):1329-39 Details
Owen AM, Iddon JL, Hodges JR, Summers BA, Robbins TW (1997), “Spatial and non-spatial working memory at different stages of Parkinson's disease.” Neuropsychologia 35(4):519-32 Details
Pantelis C, Barnes TR, Nelson HE, Tanner S, Weatherley L, Owen AM, Robbins TW (1997), “Frontal-striatal cognitive deficits in patients with chronic schizophrenia.” Brain 120 ( Pt 10):1823-43 Details
1996
Baker SC, Rogers RD, Owen AM, Frith CD, Dolan RJ, Frackowiak RS, Robbins TW (1996), “Neural systems engaged by planning: a PET study of the Tower of London task.” Neuropsychologia 34(6):515-26 Details
Doyon J, Owen AM, Petrides M, Sziklas V, Evans AC (1996), “Functional anatomy of visuomotor skill learning in human subjects examined with positron emission tomography.” Eur J Neurosci 8(4):637-48 Details
Owen AM, Doyon J, Petrides M, Evans AC (1996), “Planning and spatial working memory: a positron emission tomography study in humans.” Eur J Neurosci 8(2):353-64 Details
Owen AM, Evans AC, Petrides M (1996), “Evidence for a two-stage model of spatial working memory processing within the lateral frontal cortex: a positron emission tomography study.” Cereb Cortex 6(1):31-8 Details
Owen AM, Milner B, Petrides M, Evans AC (1996), “Memory for object features versus memory for object location: a positron-emission tomography study of encoding and retrieval processes.” Proc Natl Acad Sci U S A 93(17):9212-7 Details
Owen AM, Morris RG, Sahakian BJ, Polkey CE, Robbins TW (1996), “Double dissociations of memory and executive functions in working memory tasks following frontal lobe excisions, temporal lobe excisions or amygdalo-hippocampectomy in man.” Brain 119 ( Pt 5):1597-615 Details
Veale DM, Sahakian BJ, Owen AM, Marks IM (1996), “Specific cognitive deficits in tests sensitive to frontal lobe dysfunction in obsessive-compulsive disorder.” Psychol Med 26(6):1261-9 Details
1995
Owen AM, Sahakian BJ, Semple J, Polkey CE, Robbins TW (1995), “Visuo-spatial short-term recognition memory and learning after temporal lobe excisions, frontal lobe excisions or amygdalo-hippocampectomy in man.” Neuropsychologia 33(1):1-24 Details
1994
Robbins TW, James M, Owen AM, Lange KW, Lees AJ, Leigh PN, Marsden CD, Quinn NP, Summers BA (1994), “Cognitive deficits in progressive supranuclear palsy, Parkinson's disease, and multiple system atrophy in tests sensitive to frontal lobe dysfunction.” J Neurol Neurosurg Psychiatry 57(1):79-88 Details
Robbins TW, James M, Owen AM, Sahakian BJ, McInnes L, Rabbitt P (1994), “Cambridge Neuropsychological Test Automated Battery (CANTAB): a factor analytic study of a large sample of normal elderly volunteers.” Dementia 5(5):266-81 Details
1993
Owen AM, Beksinska M, James M, Leigh PN, Summers BA, Marsden CD, Quinn NP, Sahakian BJ, Robbins TW (1993), “Visuospatial memory deficits at different stages of Parkinson's disease.” Neuropsychologia 31(7):627-44 Details
Owen AM, Roberts AC, Hodges JR, Summers BA, Polkey CE, Robbins TW (1993), “Contrasting mechanisms of impaired attentional set-shifting in patients with frontal lobe damage or Parkinson's disease.” Brain 116 ( Pt 5):1159-75 Details
Sahakian BJ, Owen AM, Morant NJ, Eagger SA, Boddington S, Crayton L, Crockford HA, Crooks M, Hill K, Levy R (1993), “Further analysis of the cognitive effects of tetrahydroaminoacridine (THA) in Alzheimer's disease: assessment of attentional and mnemonic function using CANTAB.” Psychopharmacology (Berl) 110(4):395-401 Details
1992
Lange KW, Robbins TW, Marsden CD, James M, Owen AM, Paul GM (1992), “L-dopa withdrawal in Parkinson's disease selectively impairs cognitive performance in tests sensitive to frontal lobe dysfunction.” Psychopharmacology (Berl) 107(2-3):394-404 Details
Owen AM, James M, Leigh PN, Summers BA, Marsden CD, Quinn NP, Lange KW, Robbins TW (1992), “Fronto-striatal cognitive deficits at different stages of Parkinson's disease.” Brain 115 ( Pt 6):1727-51 Details
Robbins TW, James M, Lange KW, Owen AM, Quinn NP, Marsden CD (1992), “Cognitive performance in multiple system atrophy.” Brain 115 Pt 1:271-91 Details
Sahakian BJ, Owen AM (1992), “Computerized assessment in neuropsychiatry using CANTAB: discussion paper.” J R Soc Med 85(7):399-402 Details
1991
Förstl H, Almeida OP, Owen AM, Burns A, Howard R (1991), “Psychiatric, neurological and medical aspects of misidentification syndromes: a review of 260 cases.” Psychol Med 21(4):905-10 Details
Owen AM, Roberts AC, Polkey CE, Sahakian BJ, Robbins TW (1991), “Extra-dimensional versus intra-dimensional set shifting performance following frontal lobe excisions, temporal lobe excisions or amygdalo-hippocampectomy in man.” Neuropsychologia 29(10):993-1006 Details
1990
Owen AM, Downes JJ, Sahakian BJ, Polkey CE, Robbins TW (1990), “Planning and spatial working memory following frontal lobe lesions in man.” Neuropsychologia 28(10):1021-34 Details


