Professor Trevor Robbins

Trevor Robbins

University position

Head of Department

Professor Trevor Robbins is pleased to consider applications from prospective PhD students.

Departments

Department of Psychology

Institutes

Behavioural and Clinical Neuroscience Institute

Email

twr2@cam.ac.uk

Home page

http://www.psychol.cam.ac.uk/people/...

Research Themes

Cognitive and Behavioural Neuroscience

Systems and Computational Neuroscience

Interests

Research interests span the areas of cognitive neuroscience, behavioural neuroscience and psychopharmacology. Main work focuses on the functions of the frontal lobes of the brain and their connections with other regions. These brain systems are relevant to such psychiatric and neurological disorders as Parkinson’s and Huntington’s disease, dementia, schizophrenia, depression, drug addiction, obsessive-compulsive disorder and attention deficit/hyperactivity disorder, as well as frontal lobe injury. The lab uses a variety of methods for studying these systems, including sophisticated psychological paradigms for investigating cognitive functions and impulsivity in both normal subjects and patients; these include the computerised CANTAB battery. Also employed are MRI or PET to determine where in the human brain various cognitive operations are carried out. We are also interested in establishing how drugs work to produce changes in brain chemistry, and how these affect behaviour.

Research Focus

Keywords

cognitive

neuroscience

dopamine

behaviour

psychopharmacology

Clinical conditions

Addiction

Alzheimer's disease

Attention deficit hyperactivity disorder

Autism

Bipolar disorder

Cognitive impairment

Dementia

Depressive disorders

Genetic disorders

Huntington's disease

Obsessive compulsive disorder

Parkinson's disease

Schizophrenia

Tourette's syndrome

Equipment

Behavioural analysis

Computational modelling

Electroencephalography (EEG)

Electrophysiological recording techniques

Immunohistochemistry

Magnetic resonance imaging (MRI)

microPET

Neuropsychological testing

Positron Emission Tomography (PET)

Collaborators

Cambridge

Roger Barker

Ed Bullmore

Luke Clark

Jeff Dalley

Barry Everitt

Paul Fletcher

Adrian Owen

Angela Roberts

Barbara Sahakian

Associated News Items


    Key publications

    Dalley JW, Fryer TD, Brichard L, Robinson ES, Theobald DE, Lääne K, Peña Y, Murphy ER, Shah Y, Probst K, Abakumova I, Aigbirhio FI, Richards HK, Hong Y, Baron JC, Everitt BJ, Robbins TW (2007), “Nucleus accumbens D2/3 receptors predict trait impulsivity and cocaine reinforcement.” Science 315(5816):1267-70 Details

    Aron AR, Fletcher PC, Bullmore ET, Sahakian BJ, Robbins TW (2003), “Stop-signal inhibition disrupted by damage to right inferior frontal gyrus in humans.” Nat Neurosci 6(2):115-6 Details

    Cardinal RN, Pennicott DR, Sugathapala CL, Robbins TW, Everitt BJ (2001), “Impulsive choice induced in rats by lesions of the nucleus accumbens core.” Science 292(5526):2499-501 Details

    Publications

    2014

    Aron AR, Robbins TW, Poldrack RA (2014), “Inhibition and the right inferior frontal cortex: one decade on.” Trends Cogn Sci 18(4):177-85 Details

    Caprioli D, Sawiak SJ, Merlo E, Theobald DE, Spoelder M, Jupp B, Voon V, Carpenter TA, Everitt BJ, Robbins TW, Dalley JW (2014), “Gamma Aminobutyric Acidergic and Neuronal Structural Markers in the Nucleus Accumbens Core Underlie Trait-like Impulsive Behavior.” Biol Psychiatry 75(2):115-23 Details

    Castrioto A, Funkiewiez A, Debû B, Cools R, Lhommée E, Ardouin C, Fraix V, Chabardès S, Robbins TW, Pollak P, Krack P (2014), “Iowa gambling task impairment in Parkinson's disease can be normalised by reduction of dopaminergic medication after subthalamic stimulation.” J Neurol Neurosurg Psychiatry Details

    Clarke HF, Cardinal RN, Rygula R, Hong YT, Fryer TD, Sawiak SJ, Ferrari V, Cockcroft G, Aigbirhio FI, Robbins TW, Roberts AC (2014), “Orbitofrontal dopamine depletion upregulates caudate dopamine and alters behavior via changes in reinforcement sensitivity.” J Neurosci 34(22):7663-76 Details

    Eagle DM, Noschang C, d'Angelo LS, Noble CA, Day JO, Dongelmans ML, Theobald DE, Mar AC, Urcelay GP, Morein-Zamir S, Robbins TW (2014), “The dopamine D2/D3 receptor agonist quinpirole increases checking-like behaviour in an operant observing response task with uncertain reinforcement: a novel possible model of OCD.” Behav Brain Res 264:207-29 Details

    Eisenegger C, Naef M, Linssen A, Clark L, Gandamaneni PK, Müller U, Robbins TW (2014), “Role of Dopamine D2 Receptors in Human Reinforcement Learning.” Neuropsychopharmacology Details

    Fineberg NA, Chamberlain SR, Goudriaan AE, Stein DJ, Vanderschuren LJ, Gillan CM, Shekar S, Gorwood PA, Voon V, Morein-Zamir S, Denys D, Sahakian BJ, Moeller FG, Robbins TW, Potenza MN (2014), “New developments in human neurocognition: clinical, genetic, and brain imaging correlates of impulsivity and compulsivity.” CNS Spectr 19(1):69-89 Details

    Gillan CM, Morein-Zamir S, Durieux AM, Fineberg NA, Sahakian BJ, Robbins TW (2014), “Obsessive-compulsive disorder patients have a reduced sense of control on the illusion of control task.” Front Psychol 5:204 Details

    Haro JM, Ayuso-Mateos JL, Bitter I, Demotes-Mainard J, Leboyer M, Lewis SW, Linszen D, Maj M, McDaid D, Meyer-Lindenberg A, Robbins TW, Schumann G, Thornicroft G, Van Der Feltz-Cornelis C, Van Os J, Wahlbeck K, Wittchen HU, Wykes T, Arango C, Bickenbach J, Brunn M, Cammarata P, Chevreul K, Evans-Lacko S, Finocchiaro C, Fiorillo A, Forsman AK, Hazo JB, Knappe S, Kuepper R, Luciano M, Miret M, Obradors-Tarragó C, Pagano G, Papp S, Walker-Tilley T (2014), “ROAMER: roadmap for mental health research in Europe.” Int J Methods Psychiatr Res 23 Suppl 1:1-14 Details

    Keeler JF, Pretsell DO, Robbins TW (2014), “Functional implications of dopamine D1 vs D2 receptors: A 'Prepare and Select' model of the striatal direct vs. indirect pathways.” Neuroscience Details

    Kehagia AA, Housden CR, Regenthal R, Barker RA, Müller U, Rowe J, Sahakian BJ, Robbins TW (2014), “Targeting impulsivity in Parkinson's disease using atomoxetine.” Brain 137(Pt 7):1986-97 Details

    Morein-Zamir S, Papmeyer M, Pertusa A, Chamberlain SR, Fineberg NA, Sahakian BJ, Mataix-Cols D, Robbins TW (2014), “The profile of executive function in OCD hoarders and hoarding disorder.” Psychiatry Res 215(3):659-67 Details

    Nombela C, Rittman T, Robbins TW, Rowe JB (2014), “Multiple modes of impulsivity in Parkinson's disease.” PLoS One 9(1):e85747 Details

    Nymberg C, Banaschewski T, Bokde AL, Büchel C, Conrod P, Flor H, Frouin V, Garavan H, Gowland P, Heinz A, Ittermann B, Mann K, Martinot JL, Nees F, Paus T, Pausova Z, Rietschel M, Robbins TW, Smolka MN, Ströhle A, Schumann G, Klingberg T, IMAGEN consortium (2014), “DRD2/ANKK1 Polymorphism Modulates the Effect of Ventral Striatal Activation on Working Memory Performance.” Neuropsychopharmacology Details

    Robbins TW, Cools R (2014), “Cognitive deficits in Parkinson's disease: a cognitive neuroscience perspective.” Mov Disord 29(5):597-607 Details

    Rygula R, Clarke HF, Cardinal RN, Cockcroft GJ, Xia J, Dalley JW, Robbins TW, Roberts AC (2014), “Role of Central Serotonin in Anticipation of Rewarding and Punishing Outcomes: Effects of Selective Amygdala or Orbitofrontal 5-HT Depletion.” Cereb Cortex Details

    Smith DG, Simon Jones P, Bullmore ET, Robbins TW, Ersche KD (2014), “Enhanced orbitofrontal cortex function and lack of attentional bias to cocaine cues in recreational stimulant users.” Biol Psychiatry 75(2):124-31 Details

    Virdee K, McArthur S, Brischoux F, Caprioli D, Ungless MA, Robbins TW, Dalley JW, Gillies GE (2014), “Antenatal glucocorticoid treatment induces adaptations in adult midbrain dopamine neurons, which underpin sexually dimorphic behavioral resilience.” Neuropsychopharmacology 39(2):339-50 Details

    Voon V, Derbyshire K, Rück C, Irvine MA, Worbe Y, Enander J, Schreiber LR, Gillan C, Fineberg NA, Sahakian BJ, Robbins TW, Harrison NA, Wood J, Daw ND, Dayan P, Grant JE, Bullmore ET (2014), “Disorders of compulsivity: a common bias towards learning habits.” Mol Psychiatry Details

    Voon V, Irvine MA, Derbyshire K, Worbe Y, Lange I, Abbott S, Morein-Zamir S, Dudley R, Caprioli D, Harrison NA, Wood J, Dalley JW, Bullmore ET, Grant JE, Robbins TW (2014), “Measuring "waiting" impulsivity in substance addictions and binge eating disorder in a novel analogue of rodent serial reaction time task.” Biol Psychiatry 75(2):148-55 Details

    Whelan R, Watts R, Orr CA, Althoff RR, Artiges E, Banaschewski T, Barker GJ, Bokde AL, Büchel C, Carvalho FM, Conrod PJ, Flor H, Fauth-Bühler M, Frouin V, Gallinat J, Gan G, Gowland P, Heinz A, Ittermann B, Lawrence C, Mann K, Martinot JL, Nees F, Ortiz N, Paillère-Martinot ML, Paus T, Pausova Z, Rietschel M, Robbins TW, Smolka MN, Ströhle A, Schumann G, Garavan H, the IMAGEN Consortium (2014), “Neuropsychosocial profiles of current and future adolescent alcohol misusers.” Nature Details

    Worbe Y, Savulich G, Voon V, Fernandez-Egea E, Robbins TW (2014), “Serotonin depletion induces 'waiting impulsivity' on the human four-choice serial reaction time task: cross-species translational significance.” Neuropsychopharmacology 39(6):1519-26 Details

    Yarnall AJ, Breen DP, Duncan GW, Khoo TK, Coleman SY, Firbank MJ, Nombela C, Winder-Rhodes S, Evans JR, Rowe JB, Mollenhauer B, Kruse N, Hudson G, Chinnery PF, O'Brien JT, Robbins TW, Wesnes K, Brooks DJ, Barker RA, Burn DJ, ICICLE-PD Study Group (2014), “Characterizing mild cognitive impairment in incident Parkinson disease: The ICICLE-PD Study.” Neurology 82(4):308-16 Details

    Ye Z, Altena E, Nombela C, Housden CR, Maxwell H, Rittman T, Huddleston C, Rae CL, Regenthal R, Sahakian BJ, Barker RA, Robbins TW, Rowe JB (2014), “Improving Response Inhibition in Parkinson's Disease with Atomoxetine.” Biol Psychiatry Details

    Ye Z, Altena E, Nombela C, Housden CR, Maxwell H, Rittman T, Huddleston C, Rae CL, Regenthal R, Sahakian BJ, Barker RA, Robbins TW, Rowe JB (2014), “Selective serotonin reuptake inhibition modulates response inhibition in Parkinson's disease.” Brain 137(Pt 4):1145-55 Details

    2013

    Bari A, Robbins TW (2013), “Inhibition and impulsivity: behavioral and neural basis of response control.” Prog Neurobiol 108:44-79 Details

    Bari A, Robbins TW (2013), “Noradrenergic versus dopaminergic modulation of impulsivity, attention and monitoring behaviour in rats performing the stop-signal task: possible relevance to ADHD.” Psychopharmacology (Berl) 230(1):89-111 Details

    Bernacer J, Corlett PR, Ramachandra P, McFarlane B, Turner DC, Clark L, Robbins TW, Fletcher PC, Murray GK (2013), “Methamphetamine-induced disruption of frontostriatal reward learning signals: relation to psychotic symptoms.” Am J Psychiatry 170(11):1326-34 Details

    Besson M, Pelloux Y, Dilleen R, Theobald DE, Lyon A, Belin-Rauscent A, Robbins TW, Dalley JW, Everitt BJ, Belin D (2013), “Cocaine modulation of frontostriatal expression of Zif268, D2, and 5-HT2c receptors in high and low impulsive rats.” Neuropsychopharmacology 38(10):1963-73 Details

    Caprioli D, Hong YT, Sawiak SJ, Ferrari V, Williamson DJ, Jupp B, Adrian Carpenter T, Aigbirhio FI, Everitt BJ, Robbins TW, Fryer TD, Dalley JW (2013), “Baseline-dependent effects of cocaine pre-exposure on impulsivity and D2/3 receptor availability in the rat striatum: possible relevance to the attention-deficit hyperactivity syndrome.” Neuropsychopharmacology 38(8):1460-71 Details

    Chamberlain SR, Robbins TW (2013), “Noradrenergic modulation of cognition: therapeutic implications.” J Psychopharmacol 27(8):694-718 Details

    Crockett MJ, Apergis-Schoute A, Herrmann B, Lieberman MD, Müller U, Robbins TW, Clark L (2013), “Serotonin modulates striatal responses to fairness and retaliation in humans.” J Neurosci 33(8):3505-13 Details

    Crockett MJ, Braams BR, Clark L, Tobler PN, Robbins TW, Kalenscher T (2013), “Restricting temptations: neural mechanisms of precommitment.” Neuron 79(2):391-401 Details

    del Campo N, Fryer TD, Hong YT, Smith R, Brichard L, Acosta-Cabronero J, Chamberlain SR, Tait R, Izquierdo D, Regenthal R, Dowson J, Suckling J, Baron JC, Aigbirhio FI, Robbins TW, Sahakian BJ, Müller U (2013), “A positron emission tomography study of nigro-striatal dopaminergic mechanisms underlying attention: implications for ADHD and its treatment.” Brain 136(Pt 11):3252-70 Details

    Ersche KD, Jones PS, Williams GB, Robbins TW, Bullmore ET (2013), “Cocaine dependence: a fast-track for brain ageing?” Mol Psychiatry 18(2):134-5 Details

    Ersche KD, Jones PS, Williams GB, Smith DG, Bullmore ET, Robbins TW (2013), “Distinctive personality traits and neural correlates associated with stimulant drug use versus familial risk of stimulant dependence.” Biol Psychiatry 74(2):137-44 Details

    Ersche KD, Williams GB, Robbins TW, Bullmore ET (2013), “Meta-analysis of structural brain abnormalities associated with stimulant drug dependence and neuroimaging of addiction vulnerability and resilience.” Curr Opin Neurobiol 23(4):615-24 Details

    Everitt BJ, Robbins TW (2013), “From the ventral to the dorsal striatum: devolving views of their roles in drug addiction.” Neurosci Biobehav Rev 37(9 Pt A):1946-54 Details

    Fernando AB, Urcelay GP, Mar AC, Dickinson A, Robbins TW (2013), “Comparison of the conditioned reinforcing properties of a safety signal and appetitive stimulus: effects of d-amphetamine and anxiolytics.” Psychopharmacology (Berl) 227(2):195-208 Details

    Gastambide F, Gilmour G, Robbins TW, Tricklebank MD (2013), “The mGlu₅ positive allosteric modulator LSN2463359 differentially modulates motor, instrumental and cognitive effects of NMDA receptor antagonists in the rat.” Neuropharmacology 64:240-7 Details

    Gastambide F, Mitchell SN, Robbins TW, Tricklebank MD, Gilmour G (2013), “Temporally distinct cognitive effects following acute administration of ketamine and phencyclidine in the rat.” Eur Neuropsychopharmacol 23(11):1414-22 Details

    Gilmour G, Arguello A, Bari A, Brown VJ, Carter C, Floresco SB, Jentsch DJ, Tait DS, Young JW, Robbins TW (2013), “Measuring the construct of executive control in schizophrenia: defining and validating translational animal paradigms for discovery research.” Neurosci Biobehav Rev 37(9 Pt B):2125-40 Details

    Giuliano C, Robbins TW, Wille DR, Bullmore ET, Everitt BJ (2013), “Attenuation of cocaine and heroin seeking by μ-opioid receptor antagonism.” Psychopharmacology (Berl) 227(1):137-47 Details

    Jenner P, Morris HR, Robbins TW, Goedert M, Hardy J, Ben-Shlomo Y, Bolam P, Burn D, Hindle JV, Brooks D (2013), “Parkinson's disease--the debate on the clinical phenomenology, aetiology, pathology and pathogenesis.” J Parkinsons Dis 3(1):1-11 Details

    Jupp B, Caprioli D, Saigal N, Reverte I, Shrestha S, Cumming P, Everitt BJ, Robbins TW, Dalley JW (2013), “Dopaminergic and GABA-ergic markers of impulsivity in rats: evidence for anatomical localisation in ventral striatum and prefrontal cortex.” Eur J Neurosci 37(9):1519-28 Details

    Kehagia AA, Barker RA, Robbins TW (2013), “Cognitive impairment in Parkinson's disease: the dual syndrome hypothesis.” Neurodegener Dis 11(2):79-92 Details

    Lustig C, Kozak R, Sarter M, Young JW, Robbins TW (2013), “CNTRICS final animal model task selection: control of attention.” Neurosci Biobehav Rev 37(9 Pt B):2099-110 Details

    Montigny C, Castellanos-Ryan N, Whelan R, Banaschewski T, Barker GJ, Büchel C, Gallinat J, Flor H, Mann K, Paillère-Martinot ML, Nees F, Lathrop M, Loth E, Paus T, Pausova Z, Rietschel M, Schumann G, Smolka MN, Struve M, Robbins TW, Garavan H, Conrod PJ, IMAGEN Consortium (2013), “A phenotypic structure and neural correlates of compulsive behaviors in adolescents.” PLoS One 8(11):e80151 Details

    Morein-Zamir S, Papmeyer M, Durieux A, Fineberg NA, Sahakian BJ, Robbins TW (2013), “Investigation of attentional bias in obsessive compulsive disorder with and without depression in visual search.” PLoS One 8(11):e80118 Details

    Morein-Zamir S, Papmeyer M, Gillan CM, Crockett MJ, Fineberg NA, Sahakian BJ, Robbins TW (2013), “Punishment promotes response control deficits in obsessive-compulsive disorder: evidence from a motivational go/no-go task.” Psychol Med 43(2):391-400 Details

    Morein-Zamir S, Simon Jones P, Bullmore ET, Robbins TW, Ersche KD (2013), “Prefrontal hypoactivity associated with impaired inhibition in stimulant-dependent individuals but evidence for hyperactivation in their unaffected siblings.” Neuropsychopharmacology 38(10):1945-53 Details

    Moreno M, Economidou D, Mar AC, López-Granero C, Caprioli D, Theobald DE, Fernando A, Newman AH, Robbins TW, Dalley JW (2013), “Divergent effects of D₂/₃ receptor activation in the nucleus accumbens core and shell on impulsivity and locomotor activity in high and low impulsive rats.” Psychopharmacology (Berl) 228(1):19-30 Details

    Müller U, Rowe JB, Rittman T, Lewis C, Robbins TW, Sahakian BJ (2013), “Effects of modafinil on non-verbal cognition, task enjoyment and creative thinking in healthy volunteers.” Neuropharmacology 64:490-5 Details

    O'Callaghan C, Moustafa AA, de Wit S, Shine JM, Robbins TW, Lewis SJ, Hornberger M (2013), “Fronto-striatal gray matter contributions to discrimination learning in Parkinson's disease.” Front Comput Neurosci 7:180 Details

    Schilling C, Kühn S, Paus T, Romanowski A, Banaschewski T, Barbot A, Barker GJ, Brühl R, Büchel C, Conrod PJ, Dalley JW, Flor H, Ittermann B, Ivanov N, Mann K, Martinot JL, Nees F, Rietschel M, Robbins TW, Smolka MN, Ströhle A, Kathmann N, Garavan H, Heinz A, Schumann G, Gallinat J, IMAGEN consortium (www.imagen-europe.com) (2013), “Cortical thickness of superior frontal cortex predicts impulsiveness and perceptual reasoning in adolescence.” Mol Psychiatry 18(5):624-30 Details

    Smith DG, Jones PS, Bullmore ET, Robbins TW, Ersche KD (2013), “Cognitive control dysfunction and abnormal frontal cortex activation in stimulant drug users and their biological siblings.” Transl Psychiatry 3:e257 Details

    Smith DG, Robbins TW (2013), “The neurobiological underpinnings of obesity and binge eating: a rationale for adopting the food addiction model.” Biol Psychiatry 73(9):804-10 Details

    Williams-Gray CH, Mason SL, Evans JR, Foltynie T, Brayne C, Robbins TW, Barker RA (2013), “The CamPaIGN study of Parkinson's disease: 10-year outlook in an incident population-based cohort.” J Neurol Neurosurg Psychiatry 84(11):1258-64 Details

    Worbe Y, Irvine M, Lange I, Kundu P, Howell NA, Harrison NA, Bullmore ET, Robbins TW, Voon V (2013), “Neuronal Correlates of Risk-Seeking Attitudes to Anticipated Losses in Binge Drinkers.” Biol Psychiatry Details

    2012

    Blakemore SJ, Robbins TW (2012), “Decision-making in the adolescent brain.” Nat Neurosci 15(9):1184-91 Details

    Crockett MJ, Clark L, Apergis-Schoute AM, Morein-Zamir S, Robbins TW (2012), “Serotonin modulates the effects of Pavlovian aversive predictions on response vigor.” Neuropsychopharmacology 37(10):2244-52 Details

    Crockett MJ, Clark L, Smillie LD, Robbins TW (2012), “The effects of acute tryptophan depletion on costly information sampling: impulsivity or aversive processing?” Psychopharmacology (Berl) 219(2):587-97 Details

    Dilleen R, Pelloux Y, Mar AC, Molander A, Robbins TW, Everitt BJ, Dalley JW, Belin D (2012), “High anxiety is a predisposing endophenotype for loss of control over cocaine, but not heroin, self-administration in rats.” Psychopharmacology (Berl) 222(1):89-97 Details

    Economidou D, Theobald DE, Robbins TW, Everitt BJ, Dalley JW (2012), “Norepinephrine and dopamine modulate impulsivity on the five-choice serial reaction time task through opponent actions in the shell and core sub-regions of the nucleus accumbens.” Neuropsychopharmacology 37(9):2057-66 Details

    Ersche KD, Jones PS, Williams GB, Turton AJ, Robbins TW, Bullmore ET (2012), “Abnormal brain structure implicated in stimulant drug addiction.” Science 335(6068):601-4 Details

    Ersche KD, Turton AJ, Chamberlain SR, Müller U, Bullmore ET, Robbins TW (2012), “Cognitive dysfunction and anxious-impulsive personality traits are endophenotypes for drug dependence.” Am J Psychiatry 169(9):926-36 Details

    Fauth-Bühler M, de Rover M, Rubia K, Garavan H, Abbott S, Clark L, Vollstädt-Klein S, Mann K, Schumann G, Robbins TW (2012), “Brain networks subserving fixed versus performance-adjusted delay stop trials in a stop signal task.” Behav Brain Res 235(1):89-97 Details

    Giuliano C, Robbins TW, Nathan PJ, Bullmore ET, Everitt BJ (2012), “Inhibition of opioid transmission at the μ-opioid receptor prevents both food seeking and binge-like eating.” Neuropsychopharmacology 37(12):2643-52 Details

    Kühn S, Romanowski A, Schilling C, Banaschewski T, Barbot A, Barker GJ, Brühl R, Büchel C, Conrod PJ, Czech K, Dalley JW, Flor H, Garavan H, Häke I, Ittermann B, Ivanov N, Mann K, Lathrop M, Loth E, Lüdemann K, Mallik C, Martinot JL, Palafox C, Poline JB, Reuter J, Rietschel M, Robbins TW, Smolka MN, Nees F, Walaszek B, Schumann G, Heinz A, Gallinat J, the IMAGEN consortium (2012), “Manual dexterity correlating with right lobule VI volume in right-handed 14-year-olds.” Neuroimage 59(2):1615-1621 Details

    Lansink CS, Jackson JC, Lankelma JV, Ito R, Robbins TW, Everitt BJ, Pennartz CM (2012), “Reward cues in space: commonalities and differences in neural coding by hippocampal and ventral striatal ensembles.” J Neurosci 32(36):12444-59 Details

    Meunier D, Ersche KD, Craig KJ, Fornito A, Merlo-Pich E, Fineberg NA, Shabbir SS, Robbins TW, Bullmore ET (2012), “Brain functional connectivity in stimulant drug dependence and obsessive-compulsive disorder.” Neuroimage 59(2):1461-8 Details

    Passamonti L, Crockett MJ, Apergis-Schoute AM, Clark L, Rowe JB, Calder AJ, Robbins TW (2012), “Effects of acute tryptophan depletion on prefrontal-amygdala connectivity while viewing facial signals of aggression.” Biol Psychiatry 71(1):36-43 Details

    Robbins TW (2012), “Animal models of neuropsychiatry revisited: a personal tribute to Teitelbaum.” Behav Brain Res 231(2):337-42 Details

    Studer B, Apergis-Schoute AM, Robbins TW, Clark L (2012), “What are the Odds? The Neural Correlates of Active Choice during Gambling.” Front Neurosci 6:46 Details

    Whelan R, Conrod PJ, Poline JB, Lourdusamy A, Banaschewski T, Barker GJ, Bellgrove MA, Büchel C, Byrne M, Cummins TD, Fauth-Bühler M, Flor H, Gallinat J, Heinz A, Ittermann B, Mann K, Martinot JL, Lalor EC, Lathrop M, Loth E, Nees F, Paus T, Rietschel M, Smolka MN, Spanagel R, Stephens DN, Struve M, Thyreau B, Vollstaedt-Klein S, Robbins TW, Schumann G, Garavan H, IMAGEN Consortium (2012), “Adolescent impulsivity phenotypes characterized by distinct brain networks.” Nat Neurosci 15(6):920-5 Details

    Wu K, O'Keeffe D, Politis M, O'Keeffe GC, Robbins TW, Bose SK, Brooks DJ, Piccini P, Barker RA (2012), “The catechol-O-methyltransferase Val(158)Met polymorphism modulates fronto-cortical dopamine turnover in early Parkinson's disease: a PET study.” Brain 135(Pt 8):2449-57 Details

    2011

    Bari A, Mar AC, Theobald DE, Elands SA, Oganya KC, Eagle DM, Robbins TW (2011), “Prefrontal and monoaminergic contributions to stop-signal task performance in rats.” J Neurosci 31(25):9254-63 Details

    Chamberlain SR, Blackwell AD, Nathan PJ, Hammond G, Robbins TW, Hodges JR, Michael A, Semple JM, Bullmore ET, Sahakian BJ (2011), “Differential cognitive deterioration in dementia: a two year longitudinal study.” J Alzheimers Dis 24(1):125-36 Details

    Chamberlain SR, Robbins TW, Winder-Rhodes S, Müller U, Sahakian BJ, Blackwell AD, Barnett JH (2011), “Translational approaches to frontostriatal dysfunction in attention-deficit/hyperactivity disorder using a computerized neuropsychological battery.” Biol Psychiatry 69(12):1192-203 Details

    Chase HW, Crockett MJ, Msetfi RM, Murphy RA, Clark L, Sahakian BJ, Robbins TW (2011), “5-HT modulation by acute tryptophan depletion of human instrumental contingency judgements.” Psychopharmacology (Berl) 213(2-3):615-23 Details

    Clarke HF, Hill GJ, Robbins TW, Roberts AC (2011), “Dopamine, but not serotonin, regulates reversal learning in the marmoset caudate nucleus.” J Neurosci 31(11):4290-7 Details

    Dalley JW, Everitt BJ, Robbins TW (2011), “Impulsivity, compulsivity, and top-down cognitive control.” Neuron 69(4):680-94 Details

    de Rover M, Pironti VA, McCabe JA, Acosta-Cabronero J, Arana FS, Morein-Zamir S, Hodges JR, Robbins TW, Fletcher PC, Nestor PJ, Sahakian BJ (2011), “Hippocampal dysfunction in patients with mild cognitive impairment: a functional neuroimaging study of a visuospatial paired associates learning task.” Neuropsychologia 49(7):2060-70 Details

    de Wit S, Standing HR, Devito EE, Robinson OJ, Ridderinkhof KR, Robbins TW, Sahakian BJ (2011), “Reliance on habits at the expense of goal-directed control following dopamine precursor depletion.” Psychopharmacology (Berl) Details

    Del Campo N, Chamberlain SR, Sahakian BJ, Robbins TW (2011), “The roles of dopamine and noradrenaline in the pathophysiology and treatment of attention-deficit/hyperactivity disorder.” Biol Psychiatry 69(12):e145-57 Details

    del Campo N, Tait RJ, Acosta-Cabronero J, Hong YT, Izquierdo-Garcia D, Smith R, Aigbirhio FI, Sahakian BJ, Müller U, Robbins TW, Fryer TD (2011), “Quantification of receptor-ligand binding potential in sub-striatal domains using probabilistic and template regions of interest.” Neuroimage 55(1):101-12 Details

    Dodds CM, Morein-Zamir S, Robbins TW (2011), “Dissociating inhibition, attention, and response control in the frontoparietal network using functional magnetic resonance imaging.” Cereb Cortex 21(5):1155-65 Details

    Eagle DM, Wong JC, Allan ME, Mar AC, Theobald DE, Robbins TW (2011), “Contrasting roles for dopamine D1 and D2 receptor subtypes in the dorsomedial striatum but not the nucleus accumbens core during behavioral inhibition in the stop-signal task in rats.” J Neurosci 31(20):7349-56 Details

    Ersche KD, Barnes A, Jones PS, Morein-Zamir S, Robbins TW, Bullmore ET (2011), “Abnormal structure of frontostriatal brain systems is associated with aspects of impulsivity and compulsivity in cocaine dependence.” Brain 134(Pt 7):2013-24 Details

    Ersche KD, Cumming P, Craig KJ, Müller U, Fineberg NA, Bullmore ET, Robbins TW (2011), “Amisulpride-induced acute akathisia in OCD: an example of dysfunctional dopamine-serotonin interactions?” J Psychopharmacol Details

    Ersche KD, Roiser JP, Abbott S, Craig KJ, Müller U, Suckling J, Ooi C, Shabbir SS, Clark L, Sahakian BJ, Fineberg NA, Merlo-Pich EV, Robbins TW, Bullmore ET (2011), “Response perseveration in stimulant dependence is associated with striatal dysfunction and can be ameliorated by a D(2/3) receptor agonist.” Biol Psychiatry 70(8):754-62 Details

    Ersche KD, Roiser JP, Lucas M, Domenici E, Robbins TW, Bullmore ET (2011), “Peripheral biomarkers of cognitive response to dopamine receptor agonist treatment.” Psychopharmacology (Berl) 214(4):779-89 Details

    Evans JR, Mason SL, Williams-Gray CH, Foltynie T, Brayne C, Robbins TW, Barker RA (2011), “The natural history of treated Parkinson's disease in an incident, community based cohort.” J Neurol Neurosurg Psychiatry 82(10):1112-8 Details

    Fernando AB, Economidou D, Theobald DE, Zou MF, Newman AH, Spoelder M, Caprioli D, Moreno M, Hipόlito L, Aspinall AT, Robbins TW, Dalley JW (2011), “Modulation of high impulsivity and attentional performance in rats by selective direct and indirect dopaminergic and noradrenergic receptor agonists.” Psychopharmacology (Berl) Details

    Gastambide F, Cotel MC, Gilmour G, O'Neill MJ, Robbins TW, Tricklebank MD (2011), “Selective Remediation of Reversal Learning Deficits in the Neurodevelopmental MAM Model of Schizophrenia by a Novel mGlu5 Positive Allosteric Modulator.” Neuropsychopharmacology Details

    Gillan CM, Papmeyer M, Morein-Zamir S, Sahakian BJ, Fineberg NA, Robbins TW, de Wit S (2011), “Disruption in the balance between goal-directed behavior and habit learning in obsessive-compulsive disorder.” Am J Psychiatry 168(7):718-26 Details

    Gorodetzky H, Sahakian BJ, Robbins TW, Ersche KD (2011), “Differences in self-reported decision-making styles in stimulant-dependent and opiate-dependent individuals.” Psychiatry Res 186(2-3):437-40 Details

    Indovina I, Robbins TW, Núñez-Elizalde AO, Dunn BD, Bishop SJ (2011), “Fear-conditioning mechanisms associated with trait vulnerability to anxiety in humans.” Neuron 69(3):563-71 Details

    Mar AC, Walker AL, Theobald DE, Eagle DM, Robbins TW (2011), “Dissociable effects of lesions to orbitofrontal cortex subregions on impulsive choice in the rat.” J Neurosci 31(17):6398-404 Details

    McNaughton PA, Robbins TW (2011), “Neuroscience cuts will hurt key areas.” Nature 471(7336):36-7 Details

    Molander AC, Mar A, Norbury A, Steventon S, Moreno M, Caprioli D, Theobald DE, Belin D, Everitt BJ, Robbins TW, Dalley JW (2011), “High impulsivity predicting vulnerability to cocaine addiction in rats: some relationship with novelty preference but not novelty reactivity, anxiety or stress.” Psychopharmacology (Berl) 215(4):721-31 Details

    Murphy ER, Fernando AB, Urcelay GP, Robinson ES, Mar AC, Theobald DE, Dalley JW, Robbins TW (2011), “Impulsive behaviour induced by both NMDA receptor antagonism and GABA(A) receptor activation in rat ventromedial prefrontal cortex.” Psychopharmacology (Berl) Details

    Nees F, Tzschoppe J, Patrick CJ, Vollstädt-Klein S, Steiner S, Poustka L, Banaschewski T, Barker GJ, Büchel C, Conrod PJ, Garavan H, Heinz A, Gallinat J, Lathrop M, Mann K, Artiges E, Paus T, Poline JB, Robbins TW, Rietschel M, Smolka MN, Spanagel R, Struve M, Loth E, Schumann G, Flor H, the IMAGEN Consortium (2011), “Determinants of Early Alcohol Use In Healthy Adolescents: The Differential Contribution of Neuroimaging and Psychological Factors.” Neuropsychopharmacology Details

    Peña-Oliver Y, Buchman VL, Dalley JW, Robbins TW, Schumann G, Ripley TL, King SL, Stephens DN (2011), “Deletion of alpha-synuclein decreases impulsivity in mice.” Genes Brain Behav Details

    Pennartz CM, Ito R, Verschure PF, Battaglia FP, Robbins TW (2011), “The hippocampal-striatal axis in learning, prediction and goal-directed behavior.” Trends Neurosci 34(10):548-59 Details

    Peters J, Bromberg U, Schneider S, Brassen S, Menz M, Banaschewski T, Conrod PJ, Flor H, Gallinat J, Garavan H, Heinz A, Itterman B, Lathrop M, Martinot JL, Paus T, Poline JB, Robbins TW, Rietschel M, Smolka M, Ströhle A, Struve M, Loth E, Schumann G, Büchel C, IMAGEN Consortium (2011), “Lower ventral striatal activation during reward anticipation in adolescent smokers.” Am J Psychiatry 168(5):540-9 Details

    Robbins TW (2011), “Cognition: the ultimate brain function.” Neuropsychopharmacology 36(1):1-2 Details

    Robbins TW, Gillan CM, Smith DG, de Wit S, Ersche KD (2011), “Neurocognitive endophenotypes of impulsivity and compulsivity: towards dimensional psychiatry.” Trends Cogn Sci Details

    Robbins TW, Kousta S (2011), “Uncovering the genetic underpinnings of cognition.” Trends Cogn Sci 15(9):375-7 Details

    Schilling C, Kühn S, Romanowski A, Banaschewski T, Barbot A, Barker GJ, Brühl R, Büchel C, Charlet K, Conrod PJ, Czech K, Dalley JW, Flor H, Häke I, Ittermann B, Ivanov N, Mann K, Lüdemann K, Martinot JL, Palafox C, Paus T, Poline JB, Reuter J, Rietschel M, Robbins TW, Smolka MN, Ströhle A, Walaszek B, Kathmann N, Schumann G, Heinz A, Garavan H, Gallinat J, the IMAGEN consortium (2011), “Common structural correlates of trait impulsiveness and perceptual reasoning in adolescence.” Hum Brain Mapp Details

    Schneider S, Peters J, Bromberg U, Brassen S, Miedl SF, Banaschewski T, Barker GJ, Conrod P, Flor H, Garavan H, Heinz A, Ittermann B, Lathrop M, Loth E, Mann K, Martinot JL, Nees F, Paus T, Rietschel M, Robbins TW, Smolka MN, Spanagel R, Ströhle A, Struve M, Schumann G, Büchel C, the IMAGEN Consortium (2011), “Risk Taking and the Adolescent Reward System: A Potential Common Link to Substance Abuse.” Am J Psychiatry Details

    2010

    Bari A, Theobald DE, Caprioli D, Mar AC, Aidoo-Micah A, Dalley JW, Robbins TW (2010), “Serotonin modulates sensitivity to reward and negative feedback in a probabilistic reversal learning task in rats.” Neuropsychopharmacology 35(6):1290-301 Details

    Barnett JH, Robbins TW, Leeson VC, Sahakian BJ, Joyce EM, Blackwell AD (2010), “Assessing cognitive function in clinical trials of schizophrenia.” Neurosci Biobehav Rev 34(8):1161-77 Details

    Besson M, Belin D, McNamara R, Theobald DE, Castel A, Beckett VL, Crittenden BM, Newman AH, Everitt BJ, Robbins TW, Dalley JW (2010), “Dissociable control of impulsivity in rats by dopamine d2/3 receptors in the core and shell subregions of the nucleus accumbens.” Neuropsychopharmacology 35(2):560-9 Details

    Boulougouris V, Robbins TW (2010), “Enhancement of spatial reversal learning by 5-HT2C receptor antagonism is neuroanatomically specific.” J Neurosci 30(3):930-8 Details

    Castañé A, Theobald DE, Robbins TW (2010), “Selective lesions of the dorsomedial striatum impair serial spatial reversal learning in rats.” Behav Brain Res 210(1):74-83 Details

    Chase HW, Camille N, Michael A, Bullmore ET, Robbins TW, Sahakian BJ (2010), “Regret and the negative evaluation of decision outcomes in major depression.” Cogn Affect Behav Neurosci 10(3):406-13 Details

    Crockett MJ, Clark L, Hauser MD, Robbins TW (2010), “Serotonin selectively influences moral judgment and behavior through effects on harm aversion.” Proc Natl Acad Sci U S A 107(40):17433-8 Details

    Crockett MJ, Clark L, Lieberman MD, Tabibnia G, Robbins TW (2010), “Impulsive choice and altruistic punishment are correlated and increase in tandem with serotonin depletion.” Emotion 10(6):855-62 Details

    Ersche KD, Bullmore ET, Craig KJ, Shabbir SS, Abbott S, Müller U, Ooi C, Suckling J, Barnes A, Sahakian BJ, Merlo-Pich EV, Robbins TW (2010), “Influence of compulsivity of drug abuse on dopaminergic modulation of attentional bias in stimulant dependence.” Arch Gen Psychiatry 67(6):632-44 Details

    Ersche KD, Turton AJ, Pradhan S, Bullmore ET, Robbins TW (2010), “Drug addiction endophenotypes: impulsive versus sensation-seeking personality traits.” Biol Psychiatry 68(8):770-3 Details

    Fineberg NA, Potenza MN, Chamberlain SR, Berlin HA, Menzies L, Bechara A, Sahakian BJ, Robbins TW, Bullmore ET, Hollander E (2010), “Probing compulsive and impulsive behaviors, from animal models to endophenotypes: a narrative review.” Neuropsychopharmacology 35(3):591-604 Details

    Kehagia AA, Barker RA, Robbins TW (2010), “Neuropsychological and clinical heterogeneity of cognitive impairment and dementia in patients with Parkinson's disease.” Lancet Neurol 9(12):1200-13 Details

    Kehagia AA, Murray GK, Robbins TW (2010), “Learning and cognitive flexibility: frontostriatal function and monoaminergic modulation.” Curr Opin Neurobiol 20(2):199-204 Details

    McNamara R, Dalley JW, Robbins TW, Everitt BJ, Belin D (2010), “Trait-like impulsivity does not predict escalation of heroin self-administration in the rat.” Psychopharmacology (Berl) 212(4):453-64 Details

    Morein-Zamir S, Craig KJ, Ersche KD, Abbott S, Muller U, Fineberg NA, Bullmore ET, Sahakian BJ, Robbins TW (2010), “Impaired visuospatial associative memory and attention in obsessive compulsive disorder but no evidence for differential dopaminergic modulation.” Psychopharmacology (Berl) 212(3):357-67 Details

    Rygula R, Walker SC, Clarke HF, Robbins TW, Roberts AC (2010), “Differential contributions of the primate ventrolateral prefrontal and orbitofrontal cortex to serial reversal learning.” J Neurosci 30(43):14552-9 Details

    2009

    Barch DM, Braver TS, Carter CS, Poldrack RA, Robbins TW (2009), “CNTRICS final task selection: executive control.” Schizophr Bull 35(1):115-35 Details

    Bari A, Eagle DM, Mar AC, Robinson ES, Robbins TW (2009), “Dissociable effects of noradrenaline, dopamine, and serotonin uptake blockade on stop task performance in rats.” Psychopharmacology (Berl) 205(2):273-83 Details

    Belin D, Jonkman S, Dickinson A, Robbins TW, Everitt BJ (2009), “Parallel and interactive learning processes within the basal ganglia: Relevance for the understanding of addiction.” Behav Brain Res 199(1):89-102 Details

    Boulougouris V, Castañé A, Robbins TW (2009), “Dopamine D2/D3 receptor agonist quinpirole impairs spatial reversal learning in rats: investigation of D3 receptor involvement in persistent behavior.” Psychopharmacology (Berl) 202(4):611-20 Details

    Boulougouris V, Chamberlain SR, Robbins TW (2009), “Cross-species models of OCD spectrum disorders.” Psychiatry Res 170(1):15-21 Details

    Boulougouris V, Robbins TW (2009), “Pre-surgical training ameliorates orbitofrontal-mediated impairments in spatial reversal learning.” Behav Brain Res 197(2):469-75 Details

    Chamberlain SR, Hampshire A, Müller U, Rubia K, Del Campo N, Craig K, Regenthal R, Suckling J, Roiser JP, Grant JE, Bullmore ET, Robbins TW, Sahakian BJ (2009), “Atomoxetine modulates right inferior frontal activation during inhibitory control: a pharmacological functional magnetic resonance imaging study.” Biol Psychiatry 65(7):550-5 Details

    Chase H, Michael A, Bullmore E, Sahakian B, Robbins T (2009), “Paradoxical enhancement of choice reaction time performance in patients with major depression.” J Psychopharmacol Details

    Chase HW, Frank MJ, Michael A, Bullmore ET, Sahakian BJ, Robbins TW (2009), “Approach and avoidance learning in patients with major depression and healthy controls: relation to anhedonia.” Psychol Med :1-8 Details

    Clark L, Roiser JP, Robbins TW, Sahakian BJ (2009), “Disrupted 'reflection' impulsivity in cannabis users but not current or former ecstasy users.” J Psychopharmacol 23(1):14-22 Details

    Clatworthy PL, Lewis SJ, Brichard L, Hong YT, Izquierdo D, Clark L, Cools R, Aigbirhio FI, Baron JC, Fryer TD, Robbins TW (2009), “Dopamine release in dissociable striatal subregions predicts the different effects of oral methylphenidate on reversal learning and spatial working memory.” J Neurosci 29(15):4690-6 Details

    Cools R, Rogers R, Barker RA, Robbins TW (2009), “Top-Down Attentional Control in Parkinson's Disease: Salient Considerations.” J Cogn Neurosci Details

    Crockett MJ, Clark L, Robbins TW (2009), “Reconciling the role of serotonin in behavioral inhibition and aversion: acute tryptophan depletion abolishes punishment-induced inhibition in humans.” J Neurosci 29(38):11993-9 Details

    Curran HV, D'Souza DC, Robbins TW, Fletcher P (2009), “Modelling psychosis.” Psychopharmacology (Berl) 206(4):513-4 Details

    Dagher A, Robbins TW (2009), “Personality, addiction, dopamine: insights from Parkinson's disease.” Neuron 61(4):502-10 Details

    Dalley JW, Fryer TD, Aigbirhio FI, Brichard L, Richards HK, Hong YT, Baron JC, Everitt BJ, Robbins TW (2009), “Modelling human drug abuse and addiction with dedicated small animal positron emission tomography.” Neuropharmacology 56 Suppl 1:9-17 Details

    Dodds CM, Clark L, Dove A, Regenthal R, Baumann F, Bullmore E, Robbins TW, Müller U (2009), “The dopamine D2 receptor antagonist sulpiride modulates striatal BOLD signal during the manipulation of information in working memory.” Psychopharmacology (Berl) Details

    Eagle DM, Lehmann O, Theobald DE, Pena Y, Zakaria R, Ghosh R, Dalley JW, Robbins TW (2009), “Serotonin depletion impairs waiting but not stop-signal reaction time in rats: implications for theories of the role of 5-HT in behavioral inhibition.” Neuropsychopharmacology 34(5):1311-21 Details

    Economidou D, Pelloux Y, Robbins TW, Dalley JW, Everitt BJ (2009), “High Impulsivity Predicts Relapse to Cocaine-Seeking After Punishment-Induced Abstinence.” Biol Psychiatry Details

    Jonkman S, Mar AC, Dickinson A, Robbins TW, Everitt BJ (2009), “The rat prelimbic cortex mediates inhibitory response control but not the consolidation of instrumental learning.” Behav Neurosci 123(4):875-85 Details

    Kehagia AA, Cools R, Barker RA, Robbins TW (2009), “Switching between abstract rules reflects disease severity but not dopaminergic status in Parkinson's disease.” Neuropsychologia 47(4):1117-27 Details

    Leeson VC, Robbins TW, Franklin C, Harrison M, Harrison I, Ron MA, Barnes TR, Joyce EM (2009), “Dissociation of long-term verbal memory and fronto-executive impairment in first-episode psychosis.” Psychol Med :1-10 Details

    Leeson VC, Robbins TW, Matheson E, Hutton SB, Ron MA, Barnes TR, Joyce EM (2009), “Discrimination learning, reversal, and set-shifting in first-episode schizophrenia: stability over six years and specific associations with medication type and disorganization syndrome.” Biol Psychiatry 66(6):586-93 Details

    Morein-Zamir S, Fineberg NA, Robbins TW, Sahakian BJ (2009), “Inhibition of thoughts and actions in obsessive-compulsive disorder: extending the endophenotype?” Psychol Med :1-10 Details

    Pezze MA, Dalley JW, Robbins TW (2009), “Remediation of attentional dysfunction in rats with lesions of the medial prefrontal cortex by intra-accumbens administration of the dopamine D(2/3) receptor antagonist sulpiride.” Psychopharmacology (Berl) 202(1-3):307-13 Details

    Robbins TW (2009), “Special issue on cognitive enhancers.” Psychopharmacology (Berl) 202(1-3):1-2 Details

    Robbins TW, Arnsten AF (2009), “The neuropsychopharmacology of fronto-executive function: monoaminergic modulation.” Annu Rev Neurosci 32:267-87 Details

    Robinson ES, Eagle DM, Economidou D, Theobald DE, Mar AC, Murphy ER, Robbins TW, Dalley JW (2009), “Behavioural characterisation of high impulsivity on the 5-choice serial reaction time task: specific deficits in 'waiting' versus 'stopping'.” Behav Brain Res 196(2):310-6 Details

    Walker SC, Robbins TW, Roberts AC (2009), “Differential contributions of dopamine and serotonin to orbitofrontal cortex function in the marmoset.” Cereb Cortex 19(4):889-98 Details

    Walker SC, Robbins TW, Roberts AC (2009), “Response disengagement on a spatial self-ordered sequencing task: effects of regionally selective excitotoxic lesions and serotonin depletion within the prefrontal cortex.” J Neurosci 29(18):6033-41 Details

    Williams-Gray CH, Evans JR, Goris A, Foltynie T, Ban M, Robbins TW, Brayne C, Kolachana BS, Weinberger DR, Sawcer SJ, Barker RA (2009), “The distinct cognitive syndromes of Parkinson's disease: 5 year follow-up of the CamPaIGN cohort.” Brain 132(Pt 11):2958-69 Details

    Winder-Rhodes S, Chamberlain S, Idris M, Robbins T, Sahakian B, Müller U (2009), “Effects of modafinil and prazosin on cognitive and physiological functions in healthy volunteers.” J Psychopharmacol Details

    Zeeb FD, Robbins TW, Winstanley CA (2009), “Serotonergic and dopaminergic modulation of gambling behavior as assessed using a novel rat gambling task.” Neuropsychopharmacology 34(10):2329-43 Details

    2008

    Bari A, Dalley JW, Robbins TW (2008), “The application of the 5-choice serial reaction time task for the assessment of visual attentional processes and impulse control in rats.” Nat Protoc 3(5):759-67 Details

    Belin D, Mar AC, Dalley JW, Robbins TW, Everitt BJ (2008), “High impulsivity predicts the switch to compulsive cocaine-taking.” Science 320(5881):1352-5 Details

    Blackwell AD, Paterson NS, Barker RA, Robbins TW, Sahakian BJ (2008), “The effects of modafinil on mood and cognition in Huntington's disease.” Psychopharmacology (Berl) 199(1):29-36 Details

    Chamberlain SR, Menzies L, Hampshire A, Suckling J, Fineberg NA, del Campo N, Aitken M, Craig K, Owen AM, Bullmore ET, Robbins TW, Sahakian BJ (2008), “Orbitofrontal dysfunction in patients with obsessive-compulsive disorder and their unaffected relatives.” Science 321(5887):421-2 Details

    Chamberlain SR, Menzies LA, Fineberg NA, Del Campo N, Suckling J, Craig K, Müller U, Robbins TW, Bullmore ET, Sahakian BJ (2008), “Grey matter abnormalities in trichotillomania: morphometric magnetic resonance imaging study.” Br J Psychiatry 193(3):216-21 Details

    Chase HW, Clark L, Sahakian BJ, Bullmore ET, Robbins TW (2008), “Dissociable roles of prefrontal subregions in self-ordered working memory performance.” Neuropsychologia 46(11):2650-61 Details

    Clark L, Bechara A, Damasio H, Aitken MR, Sahakian BJ, Robbins TW (2008), “Differential effects of insular and ventromedial prefrontal cortex lesions on risky decision-making.” Brain Details

    Clarke HF, Robbins TW, Roberts AC (2008), “Lesions of the medial striatum in monkeys produce perseverative impairments during reversal learning similar to those produced by lesions of the orbitofrontal cortex.” J Neurosci 28(43):10972-82 Details

    Cools R, Roberts AC, Robbins TW (2008), “Serotoninergic regulation of emotional and behavioural control processes.” Trends Cogn Sci 12(1):31-40 Details

    Crockett MJ, Clark L, Tabibnia G, Lieberman MD, Robbins TW (2008), “Serotonin modulates behavioral reactions to unfairness.” Science 320(5884):1739 Details

    Di Ciano P, Robbins TW, Everitt BJ (2008), “Differential effects of nucleus accumbens core, shell, or dorsal striatal inactivations on the persistence, reacquisition, or reinstatement of responding for a drug-paired conditioned reinforcer.” Neuropsychopharmacology 33(6):1413-25 Details

    Dodds CM, Müller U, Clark L, van Loon A, Cools R, Robbins TW (2008), “Methylphenidate has differential effects on blood oxygenation level-dependent signal related to cognitive subprocesses of reversal learning.” J Neurosci 28(23):5976-82 Details

    Eagle DM, Bari A, Robbins TW (2008), “The neuropsychopharmacology of action inhibition: cross-species translation of the stop-signal and go/no-go tasks.” Psychopharmacology (Berl) 199(3):439-56 Details

    Eagle DM, Baunez C, Hutcheson DM, Lehmann O, Shah AP, Robbins TW (2008), “Stop-signal reaction-time task performance: role of prefrontal cortex and subthalamic nucleus.” Cereb Cortex 18(1):178-88 Details

    Ersche KD, Roiser JP, Robbins TW, Sahakian BJ (2008), “Chronic cocaine but not chronic amphetamine use is associated with perseverative responding in humans.” Psychopharmacology (Berl) 197(3):421-431 Details

    Everitt BJ, Belin D, Economidou D, Pelloux Y, Dalley JW, Robbins TW (2008), “Review. Neural mechanisms underlying the vulnerability to develop compulsive drug-seeking habits and addiction.” Philos Trans R Soc Lond B Biol Sci 363(1507):3125-35 Details

    Huddy VC, Aron AR, Harrison M, Barnes TR, Robbins TW, Joyce EM (2008), “Impaired conscious and preserved unconscious inhibitory processing in recent onset schizophrenia.” Psychol Med :1-10 Details

    Ito R, Robbins TW, Pennartz CM, Everitt BJ (2008), “Functional interaction between the hippocampus and nucleus accumbens shell is necessary for the acquisition of appetitive spatial context conditioning.” J Neurosci 28(27):6950-9 Details

    Krystal JH, Carter CS, Geschwind D, Manji HK, March JS, Nestler EJ, Zubieta JK, Charney DS, Goldman D, Gur RE, Lieberman JA, Roy-Byrne P, Rubinow DR, Anderson SA, Barondes S, Berman KF, Blair J, Braff DL, Brown ES, Calabrese JR, Carlezon WA Jr, Cook EH Jr, Davidson RJ, Davis M, Desimone R, Drevets WC, Duman RS, Essock SM, Faraone SV, Freedman R, Friston KJ, Gelernter J, Geller B, Gill M, Gould E, Grace AA, Grillon C, Gueorguieva R, Hariri AR, Innis RB, Jones EG, Kleinman JE, Koob GF, Krystal AD, Leibenluft E, Levinson DF, Levitt PR, Lewis DA, Liberzon I, Lipska BK, Marder SR, Markou A, Mason GF, McDougle CJ, McEwen BS, McMahon FJ, Meaney MJ, Meltzer HY, Merikangas KR, Meyer-Lindenberg A, Mirnics K, Monteggia LM, Neumeister A, O'Brien CP, Owen MJ, Pine DS, Rapoport JL, Rauch SL, Robbins TW, Rosenbaum JF, Rosenberg DR, Ross CA, Rush AJ, Sackeim HA, Sanacora G, Schatzberg AF, Shaham Y, Siever LJ, Sunderland T, Tecott LH, Thase ME, Todd RD, Weissman MM, Yehuda R, Yoshikawa T, Young EA, McCandless R (2008), “It is time to take a stand for medical research and against terrorism targeting medical scientists.” Biol Psychiatry 63(8):725-7 Details

    Menzies L, Williams GB, Chamberlain SR, Ooi C, Fineberg N, Suckling J, Sahakian BJ, Robbins TW, Bullmore ET (2008), “White matter abnormalities in patients with obsessive-compulsive disorder and their first-degree relatives.” Am J Psychiatry 165(10):1308-15 Details

    Milstein J, Dalley J, Robbins T (2008), “Methylphenidate-induced impulsivity: pharmacological antagonism by {beta}-adrenoreceptor blockade.” J Psychopharmacol Details

    Murphy ER, Robinson ES, Theobald DE, Dalley JW, Robbins TW (2008), “Contrasting effects of selective lesions of nucleus accumbens core or shell on inhibitory control and amphetamine-induced impulsive behaviour.” Eur J Neurosci 28(2):353-63 Details

    Murray GK, Cheng F, Clark L, Barnett JH, Blackwell AD, Fletcher PC, Robbins TW, Bullmore ET, Jones PB (2008), “Reinforcement and reversal learning in first-episode psychosis.” Schizophr Bull 34(5):848-55 Details

    Murray GK, Clark L, Corlett PR, Blackwell AD, Cools R, Jones PB, Robbins TW, Poustka L (2008), “Incentive motivation in first-episode psychosis: a behavioural study.” BMC Psychiatry 8:34 Details

    Murray GK, Corlett PR, Clark L, Pessiglione M, Blackwell AD, Honey G, Jones PB, Bullmore ET, Robbins TW, Fletcher PC (2008), “Substantia nigra/ventral tegmental reward prediction error disruption in psychosis.” Mol Psychiatry 13(3):239, 267-76 Details

    Robbins TW (2008), “Obituary: dr ann e. Kelley (1954-2007).” Psychopharmacology (Berl) 196(3):341-2 Details

    Robbins TW, Ersche KD, Everitt BJ (2008), “Drug addiction and the memory systems of the brain.” Ann N Y Acad Sci 1141:1-21 Details

    Robbins TW, Everitt BJ, Nutt DJ (2008), “Introduction. The neurobiology of drug addiction: new vistas.” Philos Trans R Soc Lond B Biol Sci 363(1507):3109-11 Details

    Robinson ES, Eagle DM, Mar AC, Bari A, Banerjee G, Jiang X, Dalley JW, Robbins TW (2008), “Similar effects of the selective noradrenaline reuptake inhibitor atomoxetine on three distinct forms of impulsivity in the rat.” Neuropsychopharmacology 33(5):1028-37 Details

    2007

    Barnett JH, Jones PB, Robbins TW, Müller U (2007), “Effects of the catechol-O-methyltransferase Val158Met polymorphism on executive function: a meta-analysis of the Wisconsin Card Sort Test in schizophrenia and healthy controls.” Mol Psychiatry 12(5):502-9 Details

    Baunez C, Christakou A, Chudasama Y, Forni C, Robbins TW (2007), “Bilateral high-frequency stimulation of the subthalamic nucleus on attentional performance: transient deleterious effects and enhanced motivation in both intact and parkinsonian rats.” Eur J Neurosci 25(4):1187-94 Details

    Boulougouris V, Dalley JW, Robbins TW (2007), “Effects of orbitofrontal, infralimbic and prelimbic cortical lesions on serial spatial reversal learning in the rat.” Behav Brain Res 179(2):219-28 Details

    Boulougouris V, Glennon JC, Robbins TW (2007), “Dissociable Effects of Selective 5-HT(2A) and 5-HT(2C) Receptor Antagonists on Serial Spatial Reversal Learning in Rats.” Neuropsychopharmacology Details

    Chamberlain SR, Del Campo N, Dowson J, Müller U, Clark L, Robbins TW, Sahakian BJ (2007), “Atomoxetine improved response inhibition in adults with attention deficit/hyperactivity disorder.” Biol Psychiatry 62(9):977-84 Details

    Chamberlain SR, Fineberg NA, Blackwell AD, Clark L, Robbins TW, Sahakian BJ (2007), “A neuropsychological comparison of obsessive-compulsive disorder and trichotillomania.” Neuropsychologia 45(4):654-62 Details

    Chamberlain SR, Fineberg NA, Menzies LA, Blackwell AD, Bullmore ET, Robbins TW, Sahakian BJ (2007), “Impaired cognitive flexibility and motor inhibition in unaffected first-degree relatives of patients with obsessive-compulsive disorder.” Am J Psychiatry 164(2):335-8 Details

    Chamberlain SR, Müller U, Cleary S, Robbins TW, Sahakian BJ (2007), “Atomoxetine increases salivary cortisol in healthy volunteers.” J Psychopharmacol 21(5):545-9 Details

    Chamberlain SR, Müller U, Deakin JB, Corlett PR, Dowson J, Cardinal RN, Aitken MR, Robbins TW, Sahakian BJ (2007), “Lack of deleterious effects of buspirone on cognition in healthy male volunteers.” J Psychopharmacol 21(2):210-5 Details

    Chamberlain SR, Robbins TW, Sahakian BJ (2007), “The neurobiology of attention-deficit/hyperactivity disorder.” Biol Psychiatry 61(12):1317-9 Details

    Chase HW, Clark L, Myers CE, Gluck MA, Sahakian BJ, Bullmore ET, Robbins TW (2007), “The role of the orbitofrontal cortex in human discrimination learning.” Neuropsychologia Details

    Clark L, Blackwell AD, Aron AR, Turner DC, Dowson J, Robbins TW, Sahakian BJ (2007), “Association between response inhibition and working memory in adult ADHD: a link to right frontal cortex pathology?” Biol Psychiatry 61(12):1395-401 Details

    Clarke HF, Walker SC, Dalley JW, Robbins TW, Roberts AC (2007), “Cognitive inflexibility after prefrontal serotonin depletion is behaviorally and neurochemically specific.” Cereb Cortex 17(1):18-27 Details

    Cools R, Lewis SJ, Clark L, Barker RA, Robbins TW (2007), “L-DOPA disrupts activity in the nucleus accumbens during reversal learning in Parkinson's disease.” Neuropsychopharmacology 32(1):180-9 Details

    Corlett PR, Murray GK, Honey GD, Aitken MR, Shanks DR, Robbins TW, Bullmore ET, Dickinson A, Fletcher PC (2007), “Disrupted prediction-error signal in psychosis: evidence for an associative account of delusions.” Brain 130(Pt 9):2387-400 Details

    Dalley JW, Lääne K, Theobald DE, Peña Y, Bruce CC, Huszar AC, Wojcieszek M, Everitt BJ, Robbins TW (2007), “Enduring deficits in sustained visual attention during withdrawal of intravenous methylenedioxymethamphetamine self-administration in rats: results from a comparative study with d-amphetamine and methamphetamine.” Neuropsychopharmacology 32(5):1195-206 Details

    Dalley JW, Mar AC, Economidou D, Robbins TW (2007), “Neurobehavioral mechanisms of impulsivity: Fronto-striatal systems and functional neurochemistry.” Pharmacol Biochem Behav Details

    Dowson JH, Blackwell AD, Turner DC, Harvey E, Malhotra T, Robbins TW, Sahakian BJ (2007), “Questionnaire ratings of attention-deficit/hyperactivity disorder (ADHD) in adults are associated with spatial working memory.” Eur Psychiatry 22(4):256-63 Details

    Eagle DM, Tufft MR, Goodchild HL, Robbins TW (2007), “Differential effects of modafinil and methylphenidate on stop-signal reaction time task performance in the rat, and interactions with the dopamine receptor antagonist cis-flupenthixol.” Psychopharmacology (Berl) 192(2):193-206 Details

    Everitt BJ, Hutcheson DM, Ersche KD, Pelloux Y, Dalley JW, Robbins TW (2007), “The orbital prefrontal cortex and drug addiction in laboratory animals and humans.” Ann N Y Acad Sci 1121:576-97 Details

    Mar AC, Robbins TW (2007), “Delay discounting and impulsive choice in the rat.” Curr Protoc Neurosci Chapter 8:Unit 8.22 Details

    Menzies L, Achard S, Chamberlain SR, Fineberg N, Chen CH, del Campo N, Sahakian BJ, Robbins TW, Bullmore E (2007), “Neurocognitive endophenotypes of obsessive-compulsive disorder.” Brain 130(Pt 12):3223-36 Details

    Milstein JA, Lehmann O, Theobald DE, Dalley JW, Robbins TW (2007), “Selective depletion of cortical noradrenaline by anti-dopamine beta-hydroxylase-saporin impairs attentional function and enhances the effects of guanfacine in the rat.” Psychopharmacology (Berl) 190(1):51-63 Details

    Pezze MA, Dalley JW, Robbins TW (2007), “Differential roles of dopamine D1 and D2 receptors in the nucleus accumbens in attentional performance on the five-choice serial reaction time task.” Neuropsychopharmacology 32(2):273-83 Details

    Robbins TW (2007), “Shifting and stopping: fronto-striatal substrates, neurochemical modulation and clinical implications.” Philos Trans R Soc Lond B Biol Sci 362(1481):917-32 Details

    Robbins TW, Everitt BJ (2007), “A role for mesencephalic dopamine in activation: commentary on Berridge (2006).” Psychopharmacology (Berl) 191(3):433-7 Details

    Robbins TW, Roberts AC (2007), “Differential regulation of fronto-executive function by the monoamines and acetylcholine.” Cereb Cortex 17 Suppl 1:i151-60 Details

    Roberts AC, Tomic DL, Parkinson CH, Roeling TA, Cutter DJ, Robbins TW, Everitt BJ (2007), “Forebrain connectivity of the prefrontal cortex in the marmoset monkey (Callithrix jacchus): an anterograde and retrograde tract-tracing study.” J Comp Neurol 502(1):86-112 Details

    Robinson ES, Dalley JW, Theobald DE, Glennon JC, Pezze MA, Murphy ER, Robbins TW (2007), “Opposing Roles for 5-HT(2A) and 5-HT(2C) Receptors in the Nucleus Accumbens on Inhibitory Response Control in the 5-Choice Serial Reaction Time Task.” Neuropsychopharmacology Details

    Tait DS, Brown VJ, Farovik A, Theobald DE, Dalley JW, Robbins TW (2007), “Lesions of the dorsal noradrenergic bundle impair attentional set-shifting in the rat.” Eur J Neurosci 25(12):3719-24 Details

    Williams-Gray CH, Foltynie T, Brayne CE, Robbins TW, Barker RA (2007), “Evolution of cognitive dysfunction in an incident Parkinson's disease cohort.” Brain 130(Pt 7):1787-98 Details

    Williams-Gray CH, Hampshire A, Robbins TW, Owen AM, Barker RA (2007), “Catechol O-methyltransferase Val158Met genotype influences frontoparietal activity during planning in patients with Parkinson's disease.” J Neurosci 27(18):4832-8 Details

    2006

    Chamberlain SR, Blackwell AD, Fineberg NA, Robbins TW, Sahakian BJ (2006), “Strategy implementation in obsessive-compulsive disorder and trichotillomania.” Psychol Med 36(1):91-7 Details

    Chamberlain SR, Fineberg NA, Blackwell AD, Robbins TW, Sahakian BJ (2006), “Motor inhibition and cognitive flexibility in obsessive-compulsive disorder and trichotillomania.” Am J Psychiatry 163(7):1282-4 Details

    Chamberlain SR, Müller U, Blackwell AD, Clark L, Robbins TW, Sahakian BJ (2006), “Neurochemical modulation of response inhibition and probabilistic learning in humans.” Science 311(5762):861-3 Details

    Chamberlain SR, Müller U, Blackwell AD, Robbins TW, Sahakian BJ (2006), “Noradrenergic modulation of working memory and emotional memory in humans.” Psychopharmacology (Berl) 188(4):397-407 Details

    Chamberlain SR, Müller U, Robbins TW, Sahakian BJ (2006), “Neuropharmacological modulation of cognition.” Curr Opin Neurol 19(6):607-12 Details

    Chudasama Y, Robbins TW (2006), “Functions of frontostriatal systems in cognition: comparative neuropsychopharmacological studies in rats, monkeys and humans.” Biol Psychol 73(1):19-38 Details

    Clark L, Robbins TW, Ersche KD, Sahakian BJ (2006), “Reflection impulsivity in current and former substance users.” Biol Psychiatry 60(5):515-22 Details

    Corlett PR, Honey GD, Aitken MR, Dickinson A, Shanks DR, Absalom AR, Lee M, Pomarol-Clotet E, Murray GK, McKenna PJ, Robbins TW, Bullmore ET, Fletcher PC (2006), “Frontal responses during learning predict vulnerability to the psychotogenic effects of ketamine: linking cognition, brain activity, and psychosis.” Arch Gen Psychiatry 63(6):611-21 Details

    Ersche KD, Clark L, London M, Robbins TW, Sahakian BJ (2006), “Profile of executive and memory function associated with amphetamine and opiate dependence.” Neuropsychopharmacology 31(5):1036-47 Details

    Ersche KD, Fletcher PC, Roiser JP, Fryer TD, London M, Robbins TW, Sahakian BJ (2006), “Differences in orbitofrontal activation during decision-making between methadone-maintained opiate users, heroin users and healthy volunteers.” Psychopharmacology (Berl) 188(3):364-73 Details

    Fowler L, Blackwell A, Jaffa A, Palmer R, Robbins TW, Sahakian BJ, Dowson JH (2006), “Profile of neurocognitive impairments associated with female in-patients with anorexia nervosa.” Psychol Med 36(4):517-27 Details

    Funkiewiez A, Ardouin C, Cools R, Krack P, Fraix V, Batir A, Chabardès S, Benabid AL, Robbins TW, Pollak P (2006), “Effects of levodopa and subthalamic nucleus stimulation on cognitive and affective functioning in Parkinson's disease.” Mov Disord 21(10):1656-62 Details

    Ito R, Robbins TW, McNaughton BL, Everitt BJ (2006), “Selective excitotoxic lesions of the hippocampus and basolateral amygdala have dissociable effects on appetitive cue and place conditioning based on path integration in a novel Y-maze procedure.” Eur J Neurosci 23(11):3071-80 Details

    Michell AW, Xu Z, Fritz D, Lewis SJ, Foltynie T, Williams-Gray CH, Robbins TW, Carpenter RH, Barker RA (2006), “Saccadic latency distributions in Parkinson's disease and the effects of L-dopa.” Exp Brain Res 174(1):7-18 Details

    Rahman S, Robbins TW, Hodges JR, Mehta MA, Nestor PJ, Clark L, Sahakian BJ (2006), “Methylphenidate ('Ritalin') can ameliorate abnormal risk-taking behavior in the frontal variant of frontotemporal dementia.” Neuropsychopharmacology 31(3):651-8 Details

    Robbins TW, Murphy ER (2006), “Behavioural pharmacology: 40+ years of progress, with a focus on glutamate receptors and cognition.” Trends Pharmacol Sci 27(3):141-8 Details

    Roiser JP, Blackwell AD, Cools R, Clark L, Rubinsztein DC, Robbins TW, Sahakian BJ (2006), “Serotonin transporter polymorphism mediates vulnerability to loss of incentive motivation following acute tryptophan depletion.” Neuropsychopharmacology 31(10):2264-72 Details

    Swainson R, SenGupta D, Shetty T, Watkins LH, Summers BA, Sahakian BJ, Polkey CE, Barker RA, Robbins TW (2006), “Impaired dimensional selection but intact use of reward feedback during visual discrimination learning in Parkinson's disease.” Neuropsychologia 44(8):1290-304 Details

    Talpos JC, Wilkinson LS, Robbins TW (2006), “A comparison of multiple 5-HT receptors in two tasks measuring impulsivity.” J Psychopharmacol 20(1):47-58 Details

    Walker SC, Mikheenko YP, Argyle LD, Robbins TW, Roberts AC (2006), “Selective prefrontal serotonin depletion impairs acquisition of a detour-reaching task.” Eur J Neurosci 23(11):3119-23 Details

    Winstanley CA, Eagle DM, Robbins TW (2006), “Behavioral models of impulsivity in relation to ADHD: translation between clinical and preclinical studies.” Clin Psychol Rev 26(4):379-95 Details

    Winstanley CA, Theobald DE, Dalley JW, Cardinal RN, Robbins TW (2006), “Double dissociation between serotonergic and dopaminergic modulation of medial prefrontal and orbitofrontal cortex during a test of impulsive choice.” Cereb Cortex 16(1):106-14 Details

    2005

    Chamberlain SR, Blackwell AD, Fineberg NA, Robbins TW, Sahakian BJ (2005), “The neuropsychology of obsessive compulsive disorder: the importance of failures in cognitive and behavioural inhibition as candidate endophenotypic markers.” Neurosci Biobehav Rev 29(3):399-419 Details

    Cheesman AL, Barker RA, Lewis SJ, Robbins TW, Owen AM, Brooks DJ (2005), “Lateralisation of striatal function: evidence from 18F-dopa PET in Parkinson's disease.” J Neurol Neurosurg Psychiatry 76(9):1204-10 Details

    Christakou A, Robbins TW, Everitt BJ (2005), “Prolonged neglect following unilateral disruption of a prefrontal cortical-dorsal striatal system.” Eur J Neurosci 21(3):782-92 Details

    Chudasama Y, Nathwani F, Robbins TW (2005), “D-Amphetamine remediates attentional performance in rats with dorsal prefrontal lesions.” Behav Brain Res 158(1):97-107 Details

    Clark L, Roiser JP, Cools R, Rubinsztein DC, Sahakian BJ, Robbins TW (2005), “Stop signal response inhibition is not modulated by tryptophan depletion or the serotonin transporter polymorphism in healthy volunteers: implications for the 5-HT theory of impulsivity.” Psychopharmacology (Berl) 182(4):570-8 Details

    Clarke HF, Walker SC, Crofts HS, Dalley JW, Robbins TW, Roberts AC (2005), “Prefrontal serotonin depletion affects reversal learning but not attentional set shifting.” J Neurosci 25(2):532-8 Details

    Cools R, Blackwell A, Clark L, Menzies L, Cox S, Robbins TW (2005), “Tryptophan depletion disrupts the motivational guidance of goal-directed behavior as a function of trait impulsivity.” Neuropsychopharmacology 30(7):1362-73 Details

    Cools R, Calder AJ, Lawrence AD, Clark L, Bullmore E, Robbins TW (2005), “Individual differences in threat sensitivity predict serotonergic modulation of amygdala response to fearful faces.” Psychopharmacology (Berl) 180(4):670-9 Details

    Dalley JW, Lääne K, Pena Y, Theobald DE, Everitt BJ, Robbins TW (2005), “Attentional and motivational deficits in rats withdrawn from intravenous self-administration of cocaine or heroin.” Psychopharmacology (Berl) 182(4):579-87 Details

    Dalley JW, Lääne K, Theobald DE, Armstrong HC, Corlett PR, Chudasama Y, Robbins TW (2005), “Time-limited modulation of appetitive Pavlovian memory by D1 and NMDA receptors in the nucleus accumbens.” Proc Natl Acad Sci U S A 102(17):6189-94 Details

    Dalley JW, Theobald DE, Berry D, Milstein JA, Lääne K, Everitt BJ, Robbins TW (2005), “Cognitive sequelae of intravenous amphetamine self-administration in rats: evidence for selective effects on attentional performance.” Neuropsychopharmacology 30(3):525-37 Details

    Ersche KD, Fletcher PC, Lewis SJ, Clark L, Stocks-Gee G, London M, Deakin JB, Robbins TW, Sahakian BJ (2005), “Abnormal frontal activations related to decision-making in current and former amphetamine and opiate dependent individuals.” Psychopharmacology (Berl) 180(4):612-23 Details

    Ersche KD, Roiser JP, Clark L, London M, Robbins TW, Sahakian BJ (2005), “Punishment induces risky decision-making in methadone-maintained opiate users but not in heroin users or healthy volunteers.” Neuropsychopharmacology 30(11):2115-24 Details

    Everitt BJ, Robbins TW (2005), “Neural systems of reinforcement for drug addiction: from actions to habits to compulsion.” Nat Neurosci 8(11):1481-9 Details

    Evers EA, Cools R, Clark L, van der Veen FM, Jolles J, Sahakian BJ, Robbins TW (2005), “Serotonergic modulation of prefrontal cortex during negative feedback in probabilistic reversal learning.” Neuropsychopharmacology 30(6):1138-47 Details

    Foltynie T, Lewis SG, Goldberg TE, Blackwell AD, Kolachana BS, Weinberger DR, Robbins TW, Barker RA (2005), “The BDNF Val66Met polymorphism has a gender specific influence on planning ability in Parkinson's disease.” J Neurol 252(7):833-8 Details

    Ito R, Everitt BJ, Robbins TW (2005), “The hippocampus and appetitive Pavlovian conditioning: effects of excitotoxic hippocampal lesions on conditioned locomotor activity and autoshaping.” Hippocampus 15(6):713-21 Details

    Lewis SJ, Foltynie T, Blackwell AD, Robbins TW, Owen AM, Barker RA (2005), “Heterogeneity of Parkinson's disease in the early clinical stages using a data driven approach.” J Neurol Neurosurg Psychiatry 76(3):343-8 Details

    Lewis SJ, Slabosz A, Robbins TW, Barker RA, Owen AM (2005), “Dopaminergic basis for deficits in working memory but not attentional set-shifting in Parkinson's disease.” Neuropsychologia 43(6):823-32 Details

    Müller U, Clark L, Lam ML, Moore RM, Murphy CL, Richmond NK, Sandhu RS, Wilkins IA, Menon DK, Sahakian BJ, Robbins TW (2005), “Lack of effects of guanfacine on executive and memory functions in healthy male volunteers.” Psychopharmacology (Berl) 182(2):205-13 Details

    Müller U, Suckling J, Zelaya F, Honey G, Faessel H, Williams SC, Routledge C, Brown J, Robbins TW, Bullmore ET (2005), “Plasma level-dependent effects of methylphenidate on task-related functional magnetic resonance imaging signal changes.” Psychopharmacology (Berl) 180(4):624-33 Details

    Murphy ER, Dalley JW, Robbins TW (2005), “Local glutamate receptor antagonism in the rat prefrontal cortex disrupts response inhibition in a visuospatial attentional task.” Psychopharmacology (Berl) 179(1):99-107 Details

    Nuechterlein KH, Robbins TW, Einat H (2005), “Distinguishing separable domains of cognition in human and animal studies: what separations are optimal for targeting interventions? A summary of recommendations from breakout group 2 at the measurement and treatment research to improve cognition in schizophrenia new approaches conference.” Schizophr Bull 31(4):870-4 Details

    Robbins TW (2005), “Chemistry of the mind: neurochemical modulation of prefrontal cortical function.” J Comp Neurol 493(1):140-6 Details

    Robbins TW (2005), “Synthesizing schizophrenia: a bottom-up, symptomatic approach.” Schizophr Bull 31(4):854-64 Details

    Robbins TW (2005), “Controlling stress: how the brain protects itself from depression.” Nat Neurosci 8(3):261-2 Details

    Watkins LH, Sahakian BJ, Robertson MM, Veale DM, Rogers RD, Pickard KM, Aitken MR, Robbins TW (2005), “Executive function in Tourette's syndrome and obsessive-compulsive disorder.” Psychol Med 35(4):571-82 Details

    Winstanley CA, Baunez C, Theobald DE, Robbins TW (2005), “Lesions to the subthalamic nucleus decrease impulsive choice but impair autoshaping in rats: the importance of the basal ganglia in Pavlovian conditioning and impulse control.” Eur J Neurosci 21(11):3107-16 Details

    Winstanley CA, Theobald DE, Dalley JW, Robbins TW (2005), “Interactions between serotonin and dopamine in the control of impulsive choice in rats: therapeutic implications for impulse control disorders.” Neuropsychopharmacology 30(4):669-82 Details

    2004

    Aron AR, Monsell S, Sahakian BJ, Robbins TW (2004), “A componential analysis of task-switching deficits associated with lesions of left and right frontal cortex.” Brain 127(Pt 7):1561-73 Details

    Aron AR, Robbins TW, Poldrack RA (2004), “Inhibition and the right inferior frontal cortex.” Trends Cogn Sci 8(4):170-7 Details

    Blackwell AD, Sahakian BJ, Vesey R, Semple JM, Robbins TW, Hodges JR (2004), “Detecting dementia: novel neuropsychological markers of preclinical Alzheimer's disease.” Dement Geriatr Cogn Disord 17(1-2):42-8 Details

    Cardinal RN, Winstanley CA, Robbins TW, Everitt BJ (2004), “Limbic corticostriatal systems and delayed reinforcement.” Ann N Y Acad Sci 1021:33-50 Details

    Christakou A, Robbins TW, Everitt BJ (2004), “Prefrontal cortical-ventral striatal interactions involved in affective modulation of attentional performance: implications for corticostriatal circuit function.” J Neurosci 24(4):773-80 Details

    Chudasama Y, Dalley JW, Nathwani F, Bouger P, Robbins TW (2004), “Cholinergic modulation of visual attention and working memory: dissociable effects of basal forebrain 192-IgG-saporin lesions and intraprefrontal infusions of scopolamine.” Learn Mem 11(1):78-86 Details

    Chudasama Y, Robbins TW (2004), “Dopaminergic modulation of visual attention and working memory in the rodent prefrontal cortex.” Neuropsychopharmacology 29(9):1628-36 Details

    Chudasama Y, Robbins TW (2004), “Psychopharmacological approaches to modulating attention in the five-choice serial reaction time task: implications for schizophrenia.” Psychopharmacology (Berl) 174(1):86-98 Details

    Clark L, Cools R, Robbins TW (2004), “The neuropsychology of ventral prefrontal cortex: decision-making and reversal learning.” Brain Cogn 55(1):41-53 Details

    Clarke HF, Dalley JW, Crofts HS, Robbins TW, Roberts AC (2004), “Cognitive inflexibility after prefrontal serotonin depletion.” Science 304(5672):878-80 Details

    Cools R, Clark L, Robbins TW (2004), “Differential responses in human striatum and prefrontal cortex to changes in object and rule relevance.” J Neurosci 24(5):1129-35 Details

    Cools R, Robbins TW (2004), “Chemistry of the adaptive mind.” Philos Transact A Math Phys Eng Sci 362(1825):2871-88 Details

    Corlett PR, Aitken MR, Dickinson A, Shanks DR, Honey GD, Honey RA, Robbins TW, Bullmore ET, Fletcher PC (2004), “Prediction error during retrospective revaluation of causal associations in humans: fMRI evidence in favor of an associative model of learning.” Neuron 44(5):877-88 Details

    Dalley JW, Cardinal RN, Robbins TW (2004), “Prefrontal executive and cognitive functions in rodents: neural and neurochemical substrates.” Neurosci Biobehav Rev 28(7):771-84 Details

    Dalley JW, Theobald DE, Bouger P, Chudasama Y, Cardinal RN, Robbins TW (2004), “Cortical cholinergic function and deficits in visual attentional performance in rats following 192 IgG-saporin-induced lesions of the medial prefrontal cortex.” Cereb Cortex 14(8):922-32 Details

    Deakin JB, Aitken MR, Dowson JH, Robbins TW, Sahakian BJ (2004), “Diazepam produces disinhibitory cognitive effects in male volunteers.” Psychopharmacology (Berl) 173(1-2):88-97 Details

    Dowson JH, McLean A, Bazanis E, Toone B, Young S, Robbins TW, Sahakian B (2004), “The specificity of clinical characteristics in adults with attention-deficit/hyperactivity disorder: a comparison with patients with borderline personality disorder.” Eur Psychiatry 19(2):72-8 Details

    Dowson JH, McLean A, Bazanis E, Toone B, Young S, Robbins TW, Sahakian BJ (2004), “Impaired spatial working memory in adults with attention-deficit/hyperactivity disorder: comparisons with performance in adults with borderline personality disorder and in control subjects.” Acta Psychiatr Scand 110(1):45-54 Details

    Foltynie T, Brayne CE, Robbins TW, Barker RA (2004), “The cognitive ability of an incident cohort of Parkinson's patients in the UK. The CamPaIGN study.” Brain 127(Pt 3):550-60 Details

    Foltynie T, Goldberg TE, Lewis SG, Blackwell AD, Kolachana BS, Weinberger DR, Robbins TW, Barker RA (2004), “Planning ability in Parkinson's disease is influenced by the COMT val158met polymorphism.” Mov Disord 19(8):885-91 Details

    Ho AK, Nestor PJ, Williams GB, Bradshaw JL, Sahakian BJ, Robbins TW, Barker RA (2004), “Pseudo-neglect in Huntington's disease correlates with decreased angular gyrus density.” Neuroreport 15(6):1061-4 Details

    Ho AK, Sahakian BJ, Robbins TW, Barker RA (2004), “Random number generation in patients with symptomatic and presymptomatic Huntington's disease.” Cogn Behav Neurol 17(4):208-12 Details

    Hutton SB, Huddy V, Barnes TR, Robbins TW, Crawford TJ, Kennard C, Joyce EM (2004), “The relationship between antisaccades, smooth pursuit, and executive dysfunction in first-episode schizophrenia.” Biol Psychiatry 56(8):553-9 Details

    Ito R, Robbins TW, Everitt BJ (2004), “Differential control over cocaine-seeking behavior by nucleus accumbens core and shell.” Nat Neurosci 7(4):389-97 Details

    Lewis SJ, Dove A, Robbins TW, Barker RA, Owen AM (2004), “Striatal contributions to working memory: a functional magnetic resonance imaging study in humans.” Eur J Neurosci 19(3):755-60 Details

    Liu YP, Wilkinson LS, Robbins TW (2004), “Effects of acute and chronic buspirone on impulsive choice and efflux of 5-HT and dopamine in hippocampus, nucleus accumbens and prefrontal cortex.” Psychopharmacology (Berl) 173(1-2):175-85 Details

    McLean A, Dowson J, Toone B, Young S, Bazanis E, Robbins TW, Sahakian BJ (2004), “Characteristic neurocognitive profile associated with adult attention-deficit/hyperactivity disorder.” Psychol Med 34(4):681-92 Details

    McLean A, Rubinsztein JS, Robbins TW, Sahakian BJ (2004), “The effects of tyrosine depletion in normal healthy volunteers: implications for unipolar depression.” Psychopharmacology (Berl) 171(3):286-97 Details

    Mehta MA, Manes FF, Magnolfi G, Sahakian BJ, Robbins TW (2004), “Impaired set-shifting and dissociable effects on tests of spatial working memory following the dopamine D2 receptor antagonist sulpiride in human volunteers.” Psychopharmacology (Berl) 176(3-4):331-42 Details

    Pantelis C, Harvey CA, Plant G, Fossey E, Maruff P, Stuart GW, Brewer WJ, Nelson HE, Robbins TW, Barnes TR (2004), “Relationship of behavioural and symptomatic syndromes in schizophrenia to spatial working memory and attentional set-shifting ability.” Psychol Med 34(4):693-703 Details

    Preece MA, Dalley JW, Theobald DE, Robbins TW, Reynolds GP (2004), “Region specific changes in forebrain 5-hydroxytryptamine1A and 5-hydroxytryptamine2A receptors in isolation-reared rats: an in vitro autoradiography study.” Neuroscience 123(3):725-32 Details

    Turner DC, Aitken MR, Shanks DR, Sahakian BJ, Robbins TW, Schwarzbauer C, Fletcher PC (2004), “The role of the lateral frontal cortex in causal associative learning: exploring preventative and super-learning.” Cereb Cortex 14(8):872-80 Details

    Turner DC, Clark L, Dowson J, Robbins TW, Sahakian BJ (2004), “Modafinil improves cognition and response inhibition in adult attention-deficit/hyperactivity disorder.” Biol Psychiatry 55(10):1031-40 Details

    Turner DC, Clark L, Pomarol-Clotet E, McKenna P, Robbins TW, Sahakian BJ (2004), “Modafinil improves cognition and attentional set shifting in patients with chronic schizophrenia.” Neuropsychopharmacology 29(7):1363-73 Details

    Voorn P, Vanderschuren LJ, Groenewegen HJ, Robbins TW, Pennartz CM (2004), “Putting a spin on the dorsal-ventral divide of the striatum.” Trends Neurosci 27(8):468-74 Details

    Winstanley CA, Dalley JW, Theobald DE, Robbins TW (2004), “Fractionating impulsivity: contrasting effects of central 5-HT depletion on different measures of impulsive behavior.” Neuropsychopharmacology 29(7):1331-43 Details

    Winstanley CA, Theobald DE, Cardinal RN, Robbins TW (2004), “Contrasting roles of basolateral amygdala and orbitofrontal cortex in impulsive choice.” J Neurosci 24(20):4718-22 Details

    Winstanley CA, Theobald DE, Dalley JW, Glennon JC, Robbins TW (2004), “5-HT2A and 5-HT2C receptor antagonists have opposing effects on a measure of impulsivity: interactions with global 5-HT depletion.” Psychopharmacology (Berl) 176(3-4):376-85 Details

    Winters BD, Robbins TW, Everitt BJ (2004), “Selective cholinergic denervation of the cingulate cortex impairs the acquisition and performance of a conditional visual discrimination in rats.” Eur J Neurosci 19(2):490-6 Details

    2003

    Aron AR, Dowson JH, Sahakian BJ, Robbins TW (2003), “Methylphenidate improves response inhibition in adults with attention-deficit/hyperactivity disorder.” Biol Psychiatry 54(12):1465-8 Details

    Aron AR, Sahakian BJ, Robbins TW (2003), “Distractibility during selection-for-action: differential deficits in Huntington's disease and following frontal lobe damage.” Neuropsychologia 41(9):1137-47 Details

    Aron AR, Schlaghecken F, Fletcher PC, Bullmore ET, Eimer M, Barker R, Sahakian BJ, Robbins TW (2003), “Inhibition of subliminally primed responses is mediated by the caudate and thalamus: evidence from functional MRI and Huntington's disease.” Brain 126(Pt 3):713-23 Details

    Aron AR, Watkins L, Sahakian BJ, Monsell S, Barker RA, Robbins TW (2003), “Task-set switching deficits in early-stage Huntington's disease: implications for basal ganglia function.” J Cogn Neurosci 15(5):629-42 Details

    Cardinal RN, Parkinson JA, Marbini HD, Toner AJ, Bussey TJ, Robbins TW, Everitt BJ (2003), “Role of the anterior cingulate cortex in the control over behavior by Pavlovian conditioned stimuli in rats.” Behav Neurosci 117(3):566-87 Details

    Cazalis F, Valabrègue R, Pélégrini-Issac M, Asloun S, Robbins TW, Granon S (2003), “Individual differences in prefrontal cortical activation on the Tower of London planning task: implication for effortful processing.” Eur J Neurosci 17(10):2219-25 Details

    Chudasama Y, Baunez C, Robbins TW (2003), “Functional disconnection of the medial prefrontal cortex and subthalamic nucleus in attentional performance: evidence for corticosubthalamic interaction.” J Neurosci 23(13):5477-85 Details

    Chudasama Y, Passetti F, Rhodes SE, Lopian D, Desai A, Robbins TW (2003), “Dissociable aspects of performance on the 5-choice serial reaction time task following lesions of the dorsal anterior cingulate, infralimbic and orbitofrontal cortex in the rat: differential effects on selectivity, impulsivity and compulsivity.” Behav Brain Res 146(1-2):105-19 Details

    Chudasama Y, Robbins TW (2003), “Dissociable contributions of the orbitofrontal and infralimbic cortex to pavlovian autoshaping and discrimination reversal learning: further evidence for the functional heterogeneity of the rodent frontal cortex.” J Neurosci 23(25):8771-80 Details

    Clark L, Manes F, Antoun N, Sahakian BJ, Robbins TW (2003), “The contributions of lesion laterality and lesion volume to decision-making impairment following frontal lobe damage.” Neuropsychologia 41(11):1474-83 Details

    Cools R, Barker RA, Sahakian BJ, Robbins TW (2003), “L-Dopa medication remediates cognitive inflexibility, but increases impulsivity in patients with Parkinson's disease.” Neuropsychologia 41(11):1431-41 Details

    Eagle DM, Robbins TW (2003), “Inhibitory control in rats performing a stop-signal reaction-time task: effects of lesions of the medial striatum and d-amphetamine.” Behav Neurosci 117(6):1302-17 Details

    Eagle DM, Robbins TW (2003), “Lesions of the medial prefrontal cortex or nucleus accumbens core do not impair inhibitory control in rats performing a stop-signal reaction time task.” Behav Brain Res 146(1-2):131-44 Details

    Everitt BJ, Cardinal RN, Parkinson JA, Robbins TW (2003), “Appetitive behavior: impact of amygdala-dependent mechanisms of emotional learning.” Ann N Y Acad Sci 985:233-50 Details

    Harvey PD, Geyer MA, Robbins TW, Krystal JH (2003), “Cognition in schizophrenia: from basic science to clinical treatment.” Psychopharmacology (Berl) 169(3-4):213-4 Details

    Ho AK, Manly T, Nestor PJ, Sahakian BJ, Bak TH, Robbins TW, Rosser AE, Barker RA (2003), “A case of unilateral neglect in Huntington's disease.” Neurocase 9(3):261-73 Details

    Honey RA, Turner DC, Honey GD, Sharar SR, Kumaran D, Pomarol-Clotet E, McKenna P, Sahakian BJ, Robbins TW, Fletcher PC (2003), “Subdissociative dose ketamine produces a deficit in manipulation but not maintenance of the contents of working memory.” Neuropsychopharmacology 28(11):2037-44 Details

    Lawrence AD, Dowson J, Foxall GL, Summerfield R, Robbins TW, Sahakian BJ (2003), “Impaired visual discrimination learning in anorexia nervosa.” Appetite 40(1):85-9 Details

    Lewis SJ, Cools R, Robbins TW, Dove A, Barker RA, Owen AM (2003), “Using executive heterogeneity to explore the nature of working memory deficits in Parkinson's disease.” Neuropsychologia 41(6):645-54 Details

    Lewis SJ, Dove A, Robbins TW, Barker RA, Owen AM (2003), “Cognitive impairments in early Parkinson's disease are accompanied by reductions in activity in frontostriatal neural circuitry.” J Neurosci 23(15):6351-6 Details

    Matthews K, Robbins TW (2003), “Early experience as a determinant of adult behavioural responses to reward: the effects of repeated maternal separation in the rat.” Neurosci Biobehav Rev 27(1-2):45-55 Details

    Murphy FC, Michael A, Robbins TW, Sahakian BJ (2003), “Neuropsychological impairment in patients with major depressive disorder: the effects of feedback on task performance.” Psychol Med 33(3):455-67 Details

    Passetti F, Dalley JW, Robbins TW (2003), “Double dissociation of serotonergic and dopaminergic mechanisms on attentional performance using a rodent five-choice reaction time task.” Psychopharmacology (Berl) 165(2):136-45 Details

    Passetti F, Levita L, Robbins TW (2003), “Sulpiride alleviates the attentional impairments of rats with medial prefrontal cortex lesions.” Behav Brain Res 138(1):59-69 Details

    Pavese N, Andrews TC, Brooks DJ, Ho AK, Rosser AE, Barker RA, Robbins TW, Sahakian BJ, Dunnett SB, Piccini P (2003), “Progressive striatal and cortical dopamine receptor dysfunction in Huntington's disease: a PET study.” Brain 126(Pt 5):1127-35 Details

    Robbins TW (2003), “Dopamine and cognition.” Curr Opin Neurol 16 Suppl 2:S1-2 Details

    Turner DC, Robbins TW, Clark L, Aron AR, Dowson J, Sahakian BJ (2003), “Relative lack of cognitive effects of methylphenidate in elderly male volunteers.” Psychopharmacology (Berl) 168(4):455-64 Details

    Turner DC, Robbins TW, Clark L, Aron AR, Dowson J, Sahakian BJ (2003), “Cognitive enhancing effects of modafinil in healthy volunteers.” Psychopharmacology (Berl) 165(3):260-9 Details

    Winstanley CA, Chudasama Y, Dalley JW, Theobald DE, Glennon JC, Robbins TW (2003), “Intra-prefrontal 8-OH-DPAT and M100907 improve visuospatial attention and decrease impulsivity on the five-choice serial reaction time task in rats.” Psychopharmacology (Berl) 167(3):304-14 Details

    Winstanley CA, Dalley JW, Theobald DE, Robbins TW (2003), “Global 5-HT depletion attenuates the ability of amphetamine to decrease impulsive choice on a delay-discounting task in rats.” Psychopharmacology (Berl) 170(3):320-31 Details

    2002

    Baunez C, Amalric M, Robbins TW (2002), “Enhanced food-related motivation after bilateral lesions of the subthalamic nucleus.” J Neurosci 22(2):562-8 Details

    Bazanis E, Rogers RD, Dowson JH, Taylor P, Meux C, Staley C, Nevinson-Andrews D, Taylor C, Robbins TW, Sahakian BJ (2002), “Neurocognitive deficits in decision-making and planning of patients with DSM-III-R borderline personality disorder.” Psychol Med 32(8):1395-405 Details

    Cardinal RN, Daw N, Robbins TW, Everitt BJ (2002), “Local analysis of behaviour in the adjusting-delay task for assessing choice of delayed reinforcement.” Neural Netw 15(4-6):617-34 Details

    Cardinal RN, Parkinson JA, Lachenal G, Halkerston KM, Rudarakanchana N, Hall J, Morrison CH, Howes SR, Robbins TW, Everitt BJ (2002), “Effects of selective excitotoxic lesions of the nucleus accumbens core, anterior cingulate cortex, and central nucleus of the amygdala on autoshaping performance in rats.” Behav Neurosci 116(4):553-67 Details

    Cools R, Clark L, Owen AM, Robbins TW (2002), “Defining the neural mechanisms of probabilistic reversal learning using event-related functional magnetic resonance imaging.” J Neurosci 22(11):4563-7 Details

    Cools R, Stefanova E, Barker RA, Robbins TW, Owen AM (2002), “Dopaminergic modulation of high-level cognition in Parkinson's disease: the role of the prefrontal cortex revealed by PET.” Brain 125(Pt 3):584-94 Details

    Cox SM, Stefanova E, Johnsrude IS, Robbins TW, Owen AM (2002), “Preference formation and working memory in Parkinson's disease and normal ageing.” Neuropsychologia 40(3):317-26 Details

    Dalley JW, Chudasama Y, Theobald DE, Pettifer CL, Fletcher CM, Robbins TW (2002), “Nucleus accumbens dopamine and discriminated approach learning: interactive effects of 6-hydroxydopamine lesions and systemic apomorphine administration.” Psychopharmacology (Berl) 161(4):425-33 Details

    Dalley JW, Theobald DE, Eagle DM, Passetti F, Robbins TW (2002), “Deficits in impulse control associated with tonically-elevated serotonergic function in rat prefrontal cortex.” Neuropsychopharmacology 26(6):716-28 Details

    Dalley JW, Theobald DE, Pereira EA, Li PM, Robbins TW (2002), “Specific abnormalities in serotonin release in the prefrontal cortex of isolation-reared rats measured during behavioural performance of a task assessing visuospatial attention and impulsivity.” Psychopharmacology (Berl) 164(3):329-40 Details

    Ho AK, Sahakian BJ, Robbins TW, Barker RA, Rosser AE, Hodges JR (2002), “Verbal fluency in Huntington's disease: a longitudinal analysis of phonemic and semantic clustering and switching.” Neuropsychologia 40(8):1277-84 Details

    Hutton SB, Murphy FC, Joyce EM, Rogers RD, Cuthbert I, Barnes TR, McKenna PJ, Sahakian BJ, Robbins TW (2002), “Decision making deficits in patients with first-episode and chronic schizophrenia.” Schizophr Res 55(3):249-57 Details

    Ito R, Dalley JW, Robbins TW, Everitt BJ (2002), “Dopamine release in the dorsal striatum during cocaine-seeking behavior under the control of a drug-associated cue.” J Neurosci 22(14):6247-53 Details

    Lee AC, Robbins TW, Graham KS, Owen AM (2002), “"Pray or Prey?" dissociation of semantic memory retrieval from episodic memory processes using positron emission tomography and a novel homophone task.” Neuroimage 16(3 Pt 1):724-35 Details

    Lee AC, Robbins TW, Smith S, Calvert GA, Tracey I, Matthews P, Owen AM (2002), “Evidence for asymmetric frontal-lobe involvement in episodic memory from functional magnetic resonance imaging and patients with unilateral frontal-lobe excisions.” Neuropsychologia 40(13):2420-37 Details

    Levita L, Dalley JW, Robbins TW (2002), “Nucleus accumbens dopamine and learned fear revisited: a review and some new findings.” Behav Brain Res 137(1-2):115-27 Details

    Levita L, Dalley JW, Robbins TW (2002), “Disruption of Pavlovian contextual conditioning by excitotoxic lesions of the nucleus accumbens core.” Behav Neurosci 116(4):539-52 Details

    McGaughy J, Dalley JW, Morrison CH, Everitt BJ, Robbins TW (2002), “Selective behavioral and neurochemical effects of cholinergic lesions produced by intrabasalis infusions of 192 IgG-saporin on attentional performance in a five-choice serial reaction time task.” J Neurosci 22(5):1905-13 Details

    Murphy FC, Smith KA, Cowen PJ, Robbins TW, Sahakian BJ (2002), “The effects of tryptophan depletion on cognitive and affective processing in healthy volunteers.” Psychopharmacology (Berl) 163(1):42-53 Details

    Parkinson JA, Dalley JW, Cardinal RN, Bamford A, Fehnert B, Lachenal G, Rudarakanchana N, Halkerston KM, Robbins TW, Everitt BJ (2002), “Nucleus accumbens dopamine depletion impairs both acquisition and performance of appetitive Pavlovian approach behaviour: implications for mesoaccumbens dopamine function.” Behav Brain Res 137(1-2):149-63 Details

    Passetti F, Chudasama Y, Robbins TW (2002), “The frontal cortex of the rat and visual attentional performance: dissociable functions of distinct medial prefrontal subregions.” Cereb Cortex 12(12):1254-68 Details

    Robbins TW (2002), “The 5-choice serial reaction time task: behavioural pharmacology and functional neurochemistry.” Psychopharmacology (Berl) 163(3-4):362-80 Details

    Robbins TW (2002), “ADHD and addiction.” Nat Med 8(1):24-5 Details

    Robbins TW, Everitt BJ (2002), “Limbic-striatal memory systems and drug addiction.” Neurobiol Learn Mem 78(3):625-36 Details

    Welchew DE, Honey GD, Sharma T, Robbins TW, Bullmore ET (2002), “Multidimensional scaling of integrated neurocognitive function and schizophrenia as a disconnexion disorder.” Neuroimage 17(3):1227-39 Details

    2001

    Alderson HL, Parkinson JA, Robbins TW, Everitt BJ (2001), “The effects of excitotoxic lesions of the nucleus accumbens core or shell regions on intravenous heroin self-administration in rats.” Psychopharmacology (Berl) 153(4):455-63 Details

    Baunez C, Humby T, Eagle DM, Ryan LJ, Dunnett SB, Robbins TW (2001), “Effects of STN lesions on simple vs choice reaction time tasks in the rat: preserved motor readiness, but impaired response selection.” Eur J Neurosci 13(8):1609-16 Details

    Caine SB, Humby T, Robbins TW, Everitt BJ (2001), “Behavioral effects of psychomotor stimulants in rats with dorsal or ventral subiculum lesions: locomotion, cocaine self-administration, and prepulse inhibition of startle.” Behav Neurosci 115(4):880-94 Details

    Christakou A, Robbins TW, Everitt BJ (2001), “Functional disconnection of a prefrontal cortical-dorsal striatal system disrupts choice reaction time performance: implications for attentional function.” Behav Neurosci 115(4):812-25 Details

    Cools R, Barker RA, Sahakian BJ, Robbins TW (2001), “Enhanced or impaired cognitive function in Parkinson's disease as a function of dopaminergic medication and task demands.” Cereb Cortex 11(12):1136-43 Details

    Cools R, Barker RA, Sahakian BJ, Robbins TW (2001), “Mechanisms of cognitive set flexibility in Parkinson's disease.” Brain 124(Pt 12):2503-12 Details

    Crofts HS, Dalley JW, Collins P, Van Denderen JC, Everitt BJ, Robbins TW, Roberts AC (2001), “Differential effects of 6-OHDA lesions of the frontal cortex and caudate nucleus on the ability to acquire an attentional set.” Cereb Cortex 11(11):1015-26 Details

    Dalley JW, McGaughy J, O'Connell MT, Cardinal RN, Levita L, Robbins TW (2001), “Distinct changes in cortical acetylcholine and noradrenaline efflux during contingent and noncontingent performance of a visual attentional task.” J Neurosci 21(13):4908-14 Details

    Everitt BJ, Dickinson A, Robbins TW (2001), “The neuropsychological basis of addictive behaviour.” Brain Res Brain Res Rev 36(2-3):129-38 Details

    Hutcheson DM, Everitt BJ, Robbins TW, Dickinson A (2001), “The role of withdrawal in heroin addiction: enhances reward or promotes avoidance?” Nat Neurosci 4(9):943-7 Details

    Hutcheson DM, Parkinson JA, Robbins TW, Everitt BJ (2001), “The effects of nucleus accumbens core and shell lesions on intravenous heroin self-administration and the acquisition of drug-seeking behaviour under a second-order schedule of heroin reinforcement.” Psychopharmacology (Berl) 153(4):464-72 Details

    Inglis WL, Olmstead MC, Robbins TW (2001), “Selective deficits in attentional performance on the 5-choice serial reaction time task following pedunculopontine tegmental nucleus lesions.” Behav Brain Res 123(2):117-31 Details

    Koch M, Robbins TW (2001), “Special issue on the psychopharmacology of prepulse inhibition: basic and clinical studies.” Psychopharmacology (Berl) 156(2-3):115-6 Details

    Matthews K, Dalley JW, Matthews C, Tsai TH, Robbins TW (2001), “Periodic maternal separation of neonatal rats produces region- and gender-specific effects on biogenic amine content in postmortem adult brain.” Synapse 40(1):1-10 Details

    Mehta MA, Swainson R, Ogilvie AD, Sahakian J, Robbins TW (2001), “Improved short-term spatial memory but impaired reversal learning following the dopamine D(2) agonist bromocriptine in human volunteers.” Psychopharmacology (Berl) 159(1):10-20 Details

    Murphy FC, Rubinsztein JS, Michael A, Rogers RD, Robbins TW, Paykel ES, Sahakian BJ (2001), “Decision-making cognition in mania and depression.” Psychol Med 31(4):679-93 Details

    Pantelis C, Stuart GW, Nelson HE, Robbins TW, Barnes TR (2001), “Spatial working memory deficits in schizophrenia: relationship with tardive dyskinesia and negative symptoms.” Am J Psychiatry 158(8):1276-85 Details

    Rogers RD, Baunez C, Everitt BJ, Robbins TW (2001), “Lesions of the medial and lateral striatum in the rat produce differential deficits in attentional performance.” Behav Neurosci 115(4):799-811 Details

    Rogers RD, Robbins TW (2001), “Investigating the neurocognitive deficits associated with chronic drug misuse.” Curr Opin Neurobiol 11(2):250-7 Details

    Rubinsztein JS, Fletcher PC, Rogers RD, Ho LW, Aigbirhio FI, Paykel ES, Robbins TW, Sahakian BJ (2001), “Decision-making in mania: a PET study.” Brain 124(Pt 12):2550-63 Details

    Rubinsztein JS, Rogers RD, Riedel WJ, Mehta MA, Robbins TW, Sahakian BJ (2001), “Acute dietary tryptophan depletion impairs maintenance of "affective set" and delayed visual recognition in healthy volunteers.” Psychopharmacology (Berl) 154(3):319-26 Details

    Swainson R, Hodges JR, Galton CJ, Semple J, Michael A, Dunn BD, Iddon JL, Robbins TW, Sahakian BJ (2001), “Early detection and differential diagnosis of Alzheimer's disease and depression with neuropsychological tasks.” Dement Geriatr Cogn Disord 12(4):265-80 Details

    Swainson R, Robbins TW (2001), “Rule-abstraction deficits following a basal ganglia lesion.” Neurocase 7(5):433-43 Details

    Wallis JD, Dias R, Robbins TW, Roberts AC (2001), “Dissociable contributions of the orbitofrontal and lateral prefrontal cortex of the marmoset to performance on a detour reaching task.” Eur J Neurosci 13(9):1797-808 Details

    2000

    Alderson HL, Robbins TW, Everitt BJ (2000), “Heroin self-administration under a second-order schedule of reinforcement: acquisition and maintenance of heroin-seeking behaviour in rats.” Psychopharmacology (Berl) 153(1):120-33 Details

    Alderson HL, Robbins TW, Everitt BJ (2000), “The effects of excitotoxic lesions of the basolateral amygdala on the acquisition of heroin-seeking behaviour in rats.” Psychopharmacology (Berl) 153(1):111-9 Details

    Brasted PJ, Dunnett SB, Robbins TW (2000), “Unilateral lesions of the medial agranular cortex impair responding on a lateralised reaction time task.” Behav Brain Res 111(1-2):139-51 Details

    Brasted PJ, Watts C, Torres EM, Robbins TW, Dunnett SB (2000), “Behavioral recovery after transplantation into a rat model of Huntington's disease: dependence on anatomical connectivity and extensive postoperative training.” Behav Neurosci 114(2):431-6 Details

    Cardinal RN, Robbins TW, Everitt BJ (2000), “The effects of d-amphetamine, chlordiazepoxide, alpha-flupenthixol and behavioural manipulations on choice of signalled and unsignalled delayed reinforcement in rats.” Psychopharmacology (Berl) 152(4):362-75 Details

    Collins P, Wilkinson LS, Everitt BJ, Robbins TW, Roberts AC (2000), “The effect of dopamine depletion from the caudate nucleus of the common marmoset (Callithrix jacchus) on tests of prefrontal cognitive function.” Behav Neurosci 114(1):3-17 Details

    Everitt BJ, Robbins TW (2000), “Second-order schedules of drug reinforcement in rats and monkeys: measurement of reinforcing efficacy and drug-seeking behaviour.” Psychopharmacology (Berl) 153(1):17-30 Details

    Granon S, Passetti F, Thomas KL, Dalley JW, Everitt BJ, Robbins TW (2000), “Enhanced and impaired attentional performance after infusion of D1 dopaminergic receptor agents into rat prefrontal cortex.” J Neurosci 20(3):1208-15 Details

    Howes SR, Dalley JW, Morrison CH, Robbins TW, Everitt BJ (2000), “Leftward shift in the acquisition of cocaine self-administration in isolation-reared rats: relationship to extracellular levels of dopamine, serotonin and glutamate in the nucleus accumbens and amygdala-striatal FOS expression.” Psychopharmacology (Berl) 151(1):55-63 Details

    Inglis WL, Olmstead MC, Robbins TW (2000), “Pedunculopontine tegmental nucleus lesions impair stimulus--reward learning in autoshaping and conditioned reinforcement paradigms.” Behav Neurosci 114(2):285-94 Details

    Ito R, Dalley JW, Howes SR, Robbins TW, Everitt BJ (2000), “Dissociation in conditioned dopamine release in the nucleus accumbens core and shell in response to cocaine cues and during cocaine-seeking behavior in rats.” J Neurosci 20(19):7489-95 Details

    Lawrence AD, Watkins LH, Sahakian BJ, Hodges JR, Robbins TW (2000), “Visual object and visuospatial cognition in Huntington's disease: implications for information processing in corticostriatal circuits.” Brain 123 ( Pt 7):1349-64 Details

    Lee AC, Robbins TW, Owen AM (2000), “Episodic memory meets working memory in the frontal lobe: functional neuroimaging studies of encoding and retrieval.” Crit Rev Neurobiol 14(3-4):165-97 Details

    Lee AC, Robbins TW, Pickard JD, Owen AM (2000), “Asymmetric frontal activation during episodic memory: the effects of stimulus type on encoding and retrieval.” Neuropsychologia 38(5):677-92 Details

    McGaughy J, Everitt BJ, Robbins TW, Sarter M (2000), “The role of cortical cholinergic afferent projections in cognition: impact of new selective immunotoxins.” Behav Brain Res 115(2):251-63 Details

    Mehta MA, Owen AM, Sahakian BJ, Mavaddat N, Pickard JD, Robbins TW (2000), “Methylphenidate enhances working memory by modulating discrete frontal and parietal lobe regions in the human brain.” J Neurosci 20(6):RC65 Details

    Ornstein TJ, Iddon JL, Baldacchino AM, Sahakian BJ, London M, Everitt BJ, Robbins TW (2000), “Profiles of cognitive dysfunction in chronic amphetamine and heroin abusers.” Neuropsychopharmacology 23(2):113-26 Details

    Parkinson JA, Robbins TW, Everitt BJ (2000), “Dissociable roles of the central and basolateral amygdala in appetitive emotional learning.” Eur J Neurosci 12(1):405-13 Details

    Parkinson JA, Willoughby PJ, Robbins TW, Everitt BJ (2000), “Disconnection of the anterior cingulate cortex and nucleus accumbens core impairs Pavlovian approach behavior: further evidence for limbic cortical-ventral striatopallidal systems.” Behav Neurosci 114(1):42-63 Details

    Passetti F, Dalley JW, O'Connell MT, Everitt BJ, Robbins TW (2000), “Increased acetylcholine release in the rat medial prefrontal cortex during performance of a visual attentional task.” Eur J Neurosci 12(8):3051-8 Details

    Robbins TW (2000), “From arousal to cognition: the integrative position of the prefrontal cortex.” Prog Brain Res 126:469-83 Details

    Robbins TW (2000), “Chemical neuromodulation of frontal-executive functions in humans and other animals.” Exp Brain Res 133(1):130-8 Details

    Robbins TW, Mehta MA, Sahakian BJ (2000), “Neuroscience. Boosting working memory.” Science 290(5500):2275-6 Details

    Rogers RD, Andrews TC, Grasby PM, Brooks DJ, Robbins TW (2000), “Contrasting cortical and subcortical activations produced by attentional-set shifting and reversal learning in humans.” J Cogn Neurosci 12(1):142-62 Details

    Swainson R, Rogers RD, Sahakian BJ, Summers BA, Polkey CE, Robbins TW (2000), “Probabilistic learning and reversal deficits in patients with Parkinson's disease or frontal or temporal lobe lesions: possible adverse effects of dopaminergic medication.” Neuropsychologia 38(5):596-612 Details

    Watkins LH, Rogers RD, Lawrence AD, Sahakian BJ, Rosser AE, Robbins TW (2000), “Impaired planning but intact decision making in early Huntington's disease: implications for specific fronto-striatal pathology.” Neuropsychologia 38(8):1112-25 Details

    1999

    Baunez C, Robbins TW (1999), “Effects of dopamine depletion of the dorsal striatum and further interaction with subthalamic nucleus lesions in an attentional task in the rat.” Neuroscience 92(4):1343-56 Details

    Baunez C, Robbins TW (1999), “Effects of transient inactivation of the subthalamic nucleus by local muscimol and APV infusions on performance on the five-choice serial reaction time task in rats.” Psychopharmacology (Berl) 141(1):57-65 Details

    Brasted PJ, Robbins TW, Dunnett SB (1999), “Distinct roles for striatal subregions in mediating response processing revealed by focal excitotoxic lesions.” Behav Neurosci 113(2):253-64 Details

    Brasted PJ, Watts C, Robbins TW, Dunnett SB (1999), “Associative plasticity in striatal transplants.” Proc Natl Acad Sci U S A 96(18):10524-9 Details

    Brasted PJ, Watts C, Torres EM, Robbins TW, Dunnett SB (1999), “Behavioural recovery following striatal transplantation: effects of postoperative training and P-zone volume.” Exp Brain Res 128(4):535-8 Details

    Burns LH, Everitt BJ, Robbins TW (1999), “Effects of excitotoxic lesions of the basolateral amygdala on conditional discrimination learning with primary and conditioned reinforcement.” Behav Brain Res 100(1-2):123-33 Details

    Dalley JW, Thomas KL, Howes SR, Tsai TH, Aparicio-Legarza MI, Reynolds GP, Everitt BJ, Robbins TW (1999), “Effects of excitotoxic lesions of the rat prefrontal cortex on CREB regulation and presynaptic markers of dopamine and amino acid function in the nucleus accumbens.” Eur J Neurosci 11(4):1265-74 Details

    Eagle DM, Humby T, Dunnett SB, Robbins TW (1999), “Effects of regional striatal lesions on motor, motivational, and executive aspects of progressive-ratio performance in rats.” Behav Neurosci 113(4):718-31 Details

    Everitt BJ, Parkinson JA, Olmstead MC, Arroyo M, Robledo P, Robbins TW (1999), “Associative processes in addiction and reward. The role of amygdala-ventral striatal subsystems.” Ann N Y Acad Sci 877:412-38 Details

    Hall FS, Wilkinson LS, Humby T, Robbins TW (1999), “Maternal deprivation of neonatal rats produces enduring changes in dopamine function.” Synapse 32(1):37-43 Details

    Harrison AA, Everitt BJ, Robbins TW (1999), “Central serotonin depletion impairs both the acquisition and performance of a symmetrically reinforced go/no-go conditional visual discrimination.” Behav Brain Res 100(1-2):99-112 Details

    Lawrence AD, Sahakian BJ, Rogers RD, Hodge JR, Robbins TW (1999), “Discrimination, reversal, and shift learning in Huntington's disease: mechanisms of impaired response selection.” Neuropsychologia 37(12):1359-74 Details

    Matthews K, Robbins TW, Everitt BJ, Caine SB (1999), “Repeated neonatal maternal separation alters intravenous cocaine self-administration in adult rats.” Psychopharmacology (Berl) 141(2):123-34 Details

    Mehta MA, Sahakian BJ, McKenna PJ, Robbins TW (1999), “Systemic sulpiride in young adult volunteers simulates the profile of cognitive deficits in Parkinson's disease.” Psychopharmacology (Berl) 146(2):162-74 Details

    Middleton HC, Sharma A, Agouzoul D, Sahakian BJ, Robbins TW (1999), “Idazoxan potentiates rather than antagonizes some of the cognitive effects of clonidine.” Psychopharmacology (Berl) 145(4):401-11 Details

    Middleton HC, Sharma A, Agouzoul D, Sahakian BJ, Robbins TW (1999), “Contrasts between the cardiovascular concomitants of tests of planning and attention.” Psychophysiology 36(5):610-8 Details

    Murphy FC, Sahakian BJ, Rubinsztein JS, Michael A, Rogers RD, Robbins TW, Paykel ES (1999), “Emotional bias and inhibitory control processes in mania and depression.” Psychol Med 29(6):1307-21 Details

    Olmstead MC, Inglis WL, Bordeaux CP, Clarke EJ, Wallum NP, Everitt BJ, Robbins TW (1999), “Lesions of the pedunculopontine tegmental nucleus increase sucrose consumption but do not affect discrimination or contrast effects.” Behav Neurosci 113(4):732-43 Details

    Owen AM, Herrod NJ, Menon DK, Clark JC, Downey SP, Carpenter TA, Minhas PS, Turkheimer FE, Williams EJ, Robbins TW, Sahakian BJ, Petrides M, Pickard JD (1999), “Redefining the functional organization of working memory processes within human lateral prefrontal cortex.” Eur J Neurosci 11(2):567-74 Details

    Pantelis C, Barber FZ, Barnes TR, Nelson HE, Owen AM, Robbins TW (1999), “Comparison of set-shifting ability in patients with chronic schizophrenia and frontal lobe damage.” Schizophr Res 37(3):251-70 Details

    Parkinson JA, Olmstead MC, Burns LH, Robbins TW, Everitt BJ (1999), “Dissociation in effects of lesions of the nucleus accumbens core and shell on appetitive pavlovian approach behavior and the potentiation of conditioned reinforcement and locomotor activity by D-amphetamine.” J Neurosci 19(6):2401-11 Details

    Rahman S, Robbins TW, Sahakian BJ (1999), “Comparative cognitive neuropsychological studies of frontal lobe function: implications for therapeutic strategies in frontal variant frontotemporal dementia.” Dement Geriatr Cogn Disord 10 Suppl 1:15-28 Details

    Rahman S, Sahakian BJ, Hodges JR, Rogers RD, Robbins TW (1999), “Specific cognitive deficits in mild frontal variant frontotemporal dementia.” Brain 122 ( Pt 8):1469-93 Details

    Robbins TW, Everitt BJ (1999), “Drug addiction: bad habits add up.” Nature 398(6728):567-70 Details

    Rogers RD, Blackshaw AJ, Middleton HC, Matthews K, Hawtin K, Crowley C, Hopwood A, Wallace C, Deakin JF, Sahakian BJ, Robbins TW (1999), “Tryptophan depletion impairs stimulus-reward learning while methylphenidate disrupts attentional control in healthy young adults: implications for the monoaminergic basis of impulsive behaviour.” Psychopharmacology (Berl) 146(4):482-91 Details

    Rogers RD, Everitt BJ, Baldacchino A, Blackshaw AJ, Swainson R, Wynne K, Baker NB, Hunter J, Carthy T, Booker E, London M, Deakin JF, Sahakian BJ, Robbins TW (1999), “Dissociable deficits in the decision-making cognition of chronic amphetamine abusers, opiate abusers, patients with focal damage to prefrontal cortex, and tryptophan-depleted normal volunteers: evidence for monoaminergic mechanisms.” Neuropsychopharmacology 20(4):322-39 Details

    Rogers RD, Owen AM, Middleton HC, Williams EJ, Pickard JD, Sahakian BJ, Robbins TW (1999), “Choosing between small, likely rewards and large, unlikely rewards activates inferior and orbital prefrontal cortex.” J Neurosci 19(20):9029-38 Details

    Ward BO, Wilkinson LS, Robbins TW, Everitt BJ (1999), “Forebrain serotonin depletion facilitates the acquisition and performance of a conditional visual discrimination task in rats.” Behav Brain Res 100(1-2):51-65 Details

    Weed MR, Taffe MA, Polis I, Roberts AC, Robbins TW, Koob GF, Bloom FE, Gold LH (1999), “Performance norms for a rhesus monkey neuropsychological testing battery: acquisition and long-term performance.” Brain Res Cogn Brain Res 8(3):185-201 Details

    Young AH, Sahakian BJ, Robbins TW, Cowen PJ (1999), “The effects of chronic administration of hydrocortisone on cognitive function in normal male volunteers.” Psychopharmacology (Berl) 145(3):260-6 Details

    1998

    Arroyo M, Markou A, Robbins TW, Everitt BJ (1998), “Acquisition, maintenance and reinstatement of intravenous cocaine self-administration under a second-order schedule of reinforcement in rats: effects of conditioned cues and continuous access to cocaine.” Psychopharmacology (Berl) 140(3):331-44 Details

    Brasted PJ, Döbrössy MD, Robbins TW, Dunnett SB (1998), “Striatal lesions produce distinctive impairments in reaction time performance in two different operant chambers.” Brain Res Bull 46(6):487-93 Details

    Browne SE, Muir JL, Robbins TW, Page KJ, Everitt BJ, McCulloch J (1998), “The cerebral metabolic effects of manipulating glutamatergic systems within the basal forebrain in conscious rats.” Eur J Neurosci 10(2):649-63 Details

    Collins P, Roberts AC, Dias R, Everitt BJ, Robbins TW (1998), “Perseveration and strategy in a novel spatial self-ordered sequencing task for nonhuman primates: effects of excitotoxic lesions and dopamine depletions of the prefrontal cortex.” J Cogn Neurosci 10(3):332-54 Details

    Hall FS, Wilkinson LS, Humby T, Inglis W, Kendall DA, Marsden CA, Robbins TW (1998), “Isolation rearing in rats: pre- and postsynaptic changes in striatal dopaminergic systems.” Pharmacol Biochem Behav 59(4):859-72 Details

    Hutton SB, Puri BK, Duncan LJ, Robbins TW, Barnes TR, Joyce EM (1998), “Executive function in first-episode schizophrenia.” Psychol Med 28(2):463-73 Details

    Iddon JL, McKenna PJ, Sahakian BJ, Robbins TW (1998), “Impaired generation and use of strategy in schizophrenia: evidence from visuospatial and verbal tasks.” Psychol Med 28(5):1049-62 Details

    Lawrence AD, Hodges JR, Rosser AE, Kershaw A, ffrench-Constant C, Rubinsztein DC, Robbins TW, Sahakian BJ (1998), “Evidence for specific cognitive deficits in preclinical Huntington's disease.” Brain 121 ( Pt 7):1329-41 Details

    Lawrence AD, Weeks RA, Brooks DJ, Andrews TC, Watkins LH, Harding AE, Robbins TW, Sahakian BJ (1998), “The relationship between striatal dopamine receptor binding and cognitive performance in Huntington's disease.” Brain 121 ( Pt 7):1343-55 Details

    Olmstead MC, Robbins TW, Everitt BJ (1998), “Basal forebrain cholinergic lesions enhance conditioned approach responses to stimuli predictive of food.” Behav Neurosci 112(3):611-29 Details

    Robbins TW (1998), “Homology in behavioural pharmacology: an approach to animal models of human cognition.” Behav Pharmacol 9(7):509-19 Details

    Robbins TW, Granon S, Muir JL, Durantou F, Harrison A, Everitt BJ (1998), “Neural systems underlying arousal and attention. Implications for drug abuse.” Ann N Y Acad Sci 846:222-37 Details

    Robbins TW, James M, Owen AM, Sahakian BJ, Lawrence AD, McInnes L, Rabbitt PM (1998), “A study of performance on tests from the CANTAB battery sensitive to frontal lobe dysfunction in a large sample of normal volunteers: implications for theories of executive functioning and cognitive aging.Cambridge Neuropsychological Test Automated Battery.” J Int Neuropsychol Soc 4(5):474-90 Details

    Robledo P, Weissenborn R, Robbins TW, Everitt BJ (1998), “Effects of lesions of the nucleus basalis magnocellularis on the acquisition of cocaine self-administration in rats.” Eur J Neurosci 10(6):1946-55 Details

    Rogers RD, Sahakian BJ, Hodges JR, Polkey CE, Kennard C, Robbins TW (1998), “Dissociating executive mechanisms of task control following frontal lobe damage and Parkinson's disease.” Brain 121 ( Pt 5):815-42 Details

    Weissenborn R, Whitelaw RB, Robbins TW, Everitt BJ (1998), “Excitotoxic lesions of the mediodorsal thalamic nucleus attenuate intravenous cocaine self-administration.” Psychopharmacology (Berl) 140(2):225-32 Details

    Wilkinson LS, Humby T, Killcross AS, Torres EM, Everitt BJ, Robbins TW (1998), “Dissociations in dopamine release in medial prefrontal cortex and ventral striatum during the acquisition and extinction of classical aversive conditioning in the rat.” Eur J Neurosci 10(3):1019-26 Details

    1997

    Baunez C, Robbins TW (1997), “Bilateral lesions of the subthalamic nucleus induce multiple deficits in an attentional task in rats.” Eur J Neurosci 9(10):2086-99 Details

    Brasted PJ, Humby T, Dunnett SB, Robbins TW (1997), “Unilateral lesions of the dorsal striatum in rats disrupt responding in egocentric space.” J Neurosci 17(22):8919-26 Details

    Bussey TJ, Everitt BJ, Robbins TW (1997), “Dissociable effects of cingulate and medial frontal cortex lesions on stimulus-reward learning using a novel Pavlovian autoshaping procedure for the rat: implications for the neurobiology of emotion.” Behav Neurosci 111(5):908-19 Details

    Bussey TJ, Muir JL, Everitt BJ, Robbins TW (1997), “Triple dissociation of anterior cingulate, posterior cingulate, and medial frontal cortices on visual discrimination tasks using a touchscreen testing procedure for the rat.” Behav Neurosci 111(5):920-36 Details

    Dias R, Robbins TW, Roberts AC (1997), “Dissociable forms of inhibitory control within prefrontal cortex with an analog of the Wisconsin Card Sort Test: restriction to novel situations and independence from "on-line" processing.” J Neurosci 17(23):9285-97 Details

    Elliott R, Sahakian BJ, Herrod JJ, Robbins TW, Paykel ES (1997), “Abnormal response to negative feedback in unipolar depression: evidence for a diagnosis specific impairment.” J Neurol Neurosurg Psychiatry 63(1):74-82 Details

    Elliott R, Sahakian BJ, Matthews K, Bannerjea A, Rimmer J, Robbins TW (1997), “Effects of methylphenidate on spatial working memory and planning in healthy young adults.” Psychopharmacology (Berl) 131(2):196-206 Details

    Everitt BJ, Robbins TW (1997), “Central cholinergic systems and cognition.” Annu Rev Psychol 48:649-84 Details

    Hall FS, Humby T, Wilkinson LS, Robbins TW (1997), “The effects of isolation-rearing on preference by rats for a novel environment.” Physiol Behav 62(2):299-303 Details

    Hall FS, Humby T, Wilkinson LS, Robbins TW (1997), “The effects of isolation-rearing on sucrose consumption in rats.” Physiol Behav 62(2):291-7 Details

    Hall FS, Humby T, Wilkinson LS, Robbins TW (1997), “The effects of isolation-rearing of rats on behavioural responses to food and environmental novelty.” Physiol Behav 62(2):281-90 Details

    Harrison AA, Everitt BJ, Robbins TW (1997), “Doubly dissociable effects of median- and dorsal-raphé lesions on the performance of the five-choice serial reaction time test of attention in rats.” Behav Brain Res 89(1-2):135-49 Details

    Harrison AA, Everitt BJ, Robbins TW (1997), “Central 5-HT depletion enhances impulsive responding without affecting the accuracy of attentional performance: interactions with dopaminergic mechanisms.” Psychopharmacology (Berl) 133(4):329-42 Details

    Killcross S, Robbins TW, Everitt BJ (1997), “Different types of fear-conditioned behaviour mediated by separate nuclei within amygdala.” Nature 388(6640):377-80 Details

    Owen AM, Iddon JL, Hodges JR, Summers BA, Robbins TW (1997), “Spatial and non-spatial working memory at different stages of Parkinson's disease.” Neuropsychologia 35(4):519-32 Details

    Pantelis C, Barnes TR, Nelson HE, Tanner S, Weatherley L, Owen AM, Robbins TW (1997), “Frontal-striatal cognitive deficits in patients with chronic schizophrenia.” Brain 120 ( Pt 10):1823-43 Details

    Robbins TW (1997), “Arousal systems and attentional processes.” Biol Psychol 45(1-3):57-71 Details

    Robbins TW, McAlonan G, Muir JL, Everitt BJ (1997), “Cognitive enhancers in theory and practice: studies of the cholinergic hypothesis of cognitive deficits in Alzheimer's disease.” Behav Brain Res 83(1-2):15-23 Details

    Robbins TW, Semple J, Kumar R, Truman MI, Shorter J, Ferraro A, Fox B, McKay G, Matthews K (1997), “Effects of scopolamine on delayed-matching-to-sample and paired associates tests of visual memory and learning in human subjects: comparison with diazepam and implications for dementia.” Psychopharmacology (Berl) 134(1):95-106 Details

    Warburton EC, Harrison AA, Robbins TW, Everitt BJ (1997), “Contrasting effects of systemic and intracerebral infusions of the 5-HT1A receptor agonist 8-OH-DPAT on spatial short-term working memory in rats.” Behav Brain Res 84(1-2):247-58 Details

    Weissenborn R, Robbins TW, Everitt BJ (1997), “Effects of medial prefrontal or anterior cingulate cortex lesions on responding for cocaine under fixed-ratio and second-order schedules of reinforcement in rats.” Psychopharmacology (Berl) 134(3):242-57 Details

    Wilkinson LS, Dias R, Thomas KL, Augood SJ, Everitt BJ, Robbins TW, Roberts AC (1997), “Contrasting effects of excitotoxic lesions of the prefrontal cortex on the behavioural response to D-amphetamine and presynaptic and postsynaptic measures of striatal dopamine function in monkeys.” Neuroscience 80(3):717-30 Details

    1996

    Altman J, Everitt BJ, Glautier S, Markou A, Nutt D, Oretti R, Phillips GD, Robbins TW (1996), “The biological, social and clinical bases of drug addiction: commentary and debate.” Psychopharmacology (Berl) 125(4):285-345 Details

    Baker SC, Rogers RD, Owen AM, Frith CD, Dolan RJ, Frackowiak RS, Robbins TW (1996), “Neural systems engaged by planning: a PET study of the Tower of London task.” Neuropsychologia 34(6):515-26 Details

    Burns LH, Annett L, Kelley AE, Everitt BJ, Robbins TW (1996), “Effects of lesions to amygdala, ventral subiculum, medial prefrontal cortex, and nucleus accumbens on the reaction to novelty: implication for limbic-striatal interactions.” Behav Neurosci 110(1):60-73 Details

    Bussey TJ, Muir JL, Everitt BJ, Robbins TW (1996), “Dissociable effects of anterior and posterior cingulate cortex lesions on the acquisition of a conditional visual discrimination: facilitation of early learning vs. impairment of late learning.” Behav Brain Res 82(1):45-56 Details

    Dias R, Robbins TW, Roberts AC (1996), “Primate analogue of the Wisconsin Card Sorting Test: effects of excitotoxic lesions of the prefrontal cortex in the marmoset.” Behav Neurosci 110(5):872-86 Details

    Dias R, Robbins TW, Roberts AC (1996), “Dissociation in prefrontal cortex of affective and attentional shifts.” Nature 380(6569):69-72 Details

    Elliott R, Sahakian BJ, McKay AP, Herrod JJ, Robbins TW, Paykel ES (1996), “Neuropsychological impairments in unipolar depression: the influence of perceived failure on subsequent performance.” Psychol Med 26(5):975-89 Details

    Fray PJ, Robbins TW (1996), “CANTAB battery: proposed utility in neurotoxicology.” Neurotoxicol Teratol 18(4):499-504 Details

    Humby T, Wilkinson LS, Robbins TW, Geyer MA (1996), “Prepulses inhibit startle-induced reductions of extracellular dopamine in the nucleus accumbens of rat.” J Neurosci 16(6):2149-56 Details

    Lawrence AD, Sahakian BJ, Hodges JR, Rosser AE, Lange KW, Robbins TW (1996), “Executive and mnemonic functions in early Huntington's disease.” Brain 119 ( Pt 5):1633-45 Details

    Matthews K, Hall FS, Wilkinson LS, Robbins TW (1996), “Retarded acquisition and reduced expression of conditioned locomotor activity in adult rats following repeated early maternal separation: effects of prefeeding, d-amphetamine, dopamine antagonists and clonidine.” Psychopharmacology (Berl) 126(1):75-84 Details

    Matthews K, Wilkinson LS, Robbins TW (1996), “Repeated maternal separation of preweanling rats attenuates behavioral responses to primary and conditioned incentives in adulthood.” Physiol Behav 59(1):99-107 Details

    Molinari S, Battini R, Ferrari S, Pozzi L, Killcross AS, Robbins TW, Jouvenceau A, Billard JM, Dutar P, Lamour Y, Baker WA, Cox H, Emson PC (1996), “Deficits in memory and hippocampal long-term potentiation in mice with reduced calbindin D28K expression.” Proc Natl Acad Sci U S A 93(15):8028-33 Details

    Muir JL, Bussey TJ, Everitt BJ, Robbins TW (1996), “Dissociable effects of AMPA-induced lesions of the vertical limb diagonal band of Broca on performance of the 5-choice serial reaction time task and on acquisition of a conditional visual discrimination.” Behav Brain Res 82(1):31-44 Details

    Muir JL, Everitt BJ, Robbins TW (1996), “The cerebral cortex of the rat and visual attentional function: dissociable effects of mediofrontal, cingulate, anterior dorsolateral, and parietal cortex lesions on a five-choice serial reaction time task.” Cereb Cortex 6(3):470-81 Details

    Owen AM, Morris RG, Sahakian BJ, Polkey CE, Robbins TW (1996), “Double dissociations of memory and executive functions in working memory tasks following frontal lobe excisions, temporal lobe excisions or amygdalo-hippocampectomy in man.” Brain 119 ( Pt 5):1597-615 Details

    Robbins TW (1996), “Dissociating executive functions of the prefrontal cortex.” Philos Trans R Soc Lond B Biol Sci 351(1346):1463-70; discussion 1470-1 Details

    Robbins TW (1996), “Refining the taxonomy of memory.” Science 273(5280):1353-4 Details

    Robbins TW, Anderson EJ, Barker DR, Bradley AC, Fearnyhough C, Henson R, Hudson SR (1996), “Working memory in chess.” Mem Cognit 24(1):83-93 Details

    Robbins TW, Elliott R, Sahakian BJ (1996), “Neuropsychology--dementia and affective disorders.” Br Med Bull 52(3):627-43 Details

    Robbins TW, Everitt BJ (1996), “Neurobehavioural mechanisms of reward and motivation.” Curr Opin Neurobiol 6(2):228-36 Details

    Robledo P, Robbins TW, Everitt BJ (1996), “Effects of excitotoxic lesions of the central amygdaloid nucleus on the potentiation of reward-related stimuli by intra-accumbens amphetamine.” Behav Neurosci 110(5):981-90 Details

    Whitelaw RB, Markou A, Robbins TW, Everitt BJ (1996), “Excitotoxic lesions of the basolateral amygdala impair the acquisition of cocaine-seeking behaviour under a second-order schedule of reinforcement.” Psychopharmacology (Berl) 127(3):213-24 Details

    Wilkinson LS, Humby T, Killcross S, Robbins TW, Everitt BJ (1996), “Dissociations in hippocampal 5-hydroxytryptamine release in the rat following Pavlovian aversive conditioning to discrete and contextual stimuli.” Eur J Neurosci 8(7):1479-87 Details

    1995

    Coull JT, Middleton HC, Robbins TW, Sahakian BJ (1995), “Clonidine and diazepam have differential effects on tests of attention and learning.” Psychopharmacology (Berl) 120(3):322-32 Details

    Coull JT, Middleton HC, Robbins TW, Sahakian BJ (1995), “Contrasting effects of clonidine and diazepam on tests of working memory and planning.” Psychopharmacology (Berl) 120(3):311-21 Details

    Coull JT, Sahakian BJ, Middleton HC, Young AH, Park SB, McShane RH, Cowen PJ, Robbins TW (1995), “Differential effects of clonidine, haloperidol, diazepam and tryptophan depletion on focused attention and attentional search.” Psychopharmacology (Berl) 121(2):222-30 Details

    Elliott R, McKenna PJ, Robbins TW, Sahakian BJ (1995), “Neuropsychological evidence for frontostriatal dysfunction in schizophrenia.” Psychol Med 25(3):619-30 Details

    Gebhard R, Zilles K, Schleicher A, Everitt BJ, Robbins TW, Divac I (1995), “Parcellation of the frontal cortex of the New World monkey Callithrix jacchus by eight neurotransmitter-binding sites.” Anat Embryol (Berl) 191(6):509-17 Details

    Killcross AS, Dickinson A, Robbins TW (1995), “The on-baseline latent inhibition effect is not counterconditioning.” Psychopharmacology (Berl) 118(1):104-6 Details

    Kraemer M, Zilles K, Schleicher A, Gebhard R, Robbins TW, Everitt BJ, Divac I (1995), “Quantitative receptor autoradiography of eight different transmitter-binding sites in the hippocampus of the common marmoset, Callithrix jacchus.” Anat Embryol (Berl) 191(3):213-25 Details

    Lange KW, Sahakian BJ, Quinn NP, Marsden CD, Robbins TW (1995), “Comparison of executive and visuospatial memory function in Huntington's disease and dementia of Alzheimer type matched for degree of dementia.” J Neurol Neurosurg Psychiatry 58(5):598-606 Details

    McAlonan GM, Dawson GR, Wilkinson LO, Robbins TW, Everitt BJ (1995), “The effects of AMPA-induced lesions of the medial septum and vertical limb nucleus of the diagonal band of Broca on spatial delayed non-matching to sample and spatial learning in the water maze.” Eur J Neurosci 7(5):1034-49 Details

    McAlonan GM, Wilkinson LS, Robbins TW, Everitt BJ (1995), “The effects of AMPA-induced lesions of the septo-hippocampal cholinergic projection on aversive conditioning to explicit and contextual cues and spatial learning in the water maze.” Eur J Neurosci 7(2):281-92 Details

    Muir JL, Everitt BJ, Robbins TW (1995), “Reversal of visual attentional dysfunction following lesions of the cholinergic basal forebrain by physostigmine and nicotine but not by the 5-HT3 receptor antagonist, ondansetron.” Psychopharmacology (Berl) 118(1):82-92 Details

    Owen AM, Sahakian BJ, Semple J, Polkey CE, Robbins TW (1995), “Visuo-spatial short-term recognition memory and learning after temporal lobe excisions, frontal lobe excisions or amygdalo-hippocampectomy in man.” Neuropsychologia 33(1):1-24 Details

    Phillips GD, Howes SR, Whitelaw RB, Robbins TW, Everitt BJ (1995), “Analysis of the effects of intra-accumbens SKF-38393 and LY-171555 upon the behavioural satiety sequence.” Psychopharmacology (Berl) 117(1):82-90 Details

    Wilkinson LS, Humby T, Robbins TW, Everitt BJ (1995), “Differential effects of forebrain 5-hydroxytryptamine depletions on Pavlovian aversive conditioning to discrete and contextual stimuli in the rat.” Eur J Neurosci 7(10):2042-52 Details

    1994

    Burns LH, Everitt BJ, Kelley AE, Robbins TW (1994), “Glutamate-dopamine interactions in the ventral striatum: role in locomotor activity and responding with conditioned reinforcement.” Psychopharmacology (Berl) 115(4):516-28 Details

    Burns LH, Everitt BJ, Robbins TW (1994), “Intra-amygdala infusion of the N-methyl-D-aspartate receptor antagonist AP5 impairs acquisition but not performance of discriminated approach to an appetitive CS.” Behav Neural Biol 61(3):242-50 Details

    Hughes C, Russell J, Robbins TW (1994), “Evidence for executive dysfunction in autism.” Neuropsychologia 32(4):477-92 Details

    Killcross AS, Dickinson A, Robbins TW (1994), “Effects of the neuroleptic alpha-flupenthixol on latent inhibition in aversively- and appetitively-motivated paradigms: evidence for dopamine-reinforcer interactions.” Psychopharmacology (Berl) 115(1-2):196-205 Details

    Killcross AS, Dickinson A, Robbins TW (1994), “Amphetamine-induced disruptions of latent inhibition are reinforcer mediated: implications for animal models of schizophrenic attentional dysfunction.” Psychopharmacology (Berl) 115(1-2):185-95 Details

    Marston HM, West HL, Wilkinson LS, Everitt BJ, Robbins TW (1994), “Effects of excitotoxic lesions of the septum and vertical limb nucleus of the diagonal band of Broca on conditional visual discrimination: relationship between performance and choline acetyltransferase activity in the cingulate cortex.” J Neurosci 14(4):2009-19 Details

    Middleton HC, Ashby M, Robbins TW (1994), “Reduced plasma noradrenaline and abnormal heart rate variability in resting panic disorder patients.” Biol Psychiatry 36(12):847-9 Details

    Muir JL, Everitt BJ, Robbins TW (1994), “AMPA-induced excitotoxic lesions of the basal forebrain: a significant role for the cortical cholinergic system in attentional function.” J Neurosci 14(4):2313-26 Details

    Park SB, Coull JT, McShane RH, Young AH, Sahakian BJ, Robbins TW, Cowen PJ (1994), “Tryptophan depletion in normal volunteers produces selective impairments in learning and memory.” Neuropharmacology 33(3-4):575-88 Details

    Phillips GD, Howes SR, Whitelaw RB, Robbins TW, Everitt BJ (1994), “Isolation rearing impairs the reinforcing efficacy of intravenous cocaine or intra-accumbens d-amphetamine: impaired response to intra-accumbens D1 and D2/D3 dopamine receptor antagonists.” Psychopharmacology (Berl) 115(3):419-29 Details

    Phillips GD, Howes SR, Whitelaw RB, Wilkinson LS, Robbins TW, Everitt BJ (1994), “Isolation rearing enhances the locomotor response to cocaine and a novel environment, but impairs the intravenous self-administration of cocaine.” Psychopharmacology (Berl) 115(3):407-18 Details

    Phillips GD, Robbins TW, Everitt BJ (1994), “Bilateral intra-accumbens self-administration of d-amphetamine: antagonism with intra-accumbens SCH-23390 and sulpiride.” Psychopharmacology (Berl) 114(3):477-85 Details

    Phillips GD, Robbins TW, Everitt BJ (1994), “Mesoaccumbens dopamine-opiate interactions in the control over behaviour by a conditioned reinforcer.” Psychopharmacology (Berl) 114(2):345-59 Details

    Robbins TW, James M, Owen AM, Lange KW, Lees AJ, Leigh PN, Marsden CD, Quinn NP, Summers BA (1994), “Cognitive deficits in progressive supranuclear palsy, Parkinson's disease, and multiple system atrophy in tests sensitive to frontal lobe dysfunction.” J Neurol Neurosurg Psychiatry 57(1):79-88 Details

    Robbins TW, James M, Owen AM, Sahakian BJ, McInnes L, Rabbitt P (1994), “Cambridge Neuropsychological Test Automated Battery (CANTAB): a factor analytic study of a large sample of normal elderly volunteers.” Dementia 5(5):266-81 Details

    Roberts AC, De Salvia MA, Wilkinson LS, Collins P, Muir JL, Everitt BJ, Robbins TW (1994), “6-Hydroxydopamine lesions of the prefrontal cortex in monkeys enhance performance on an analog of the Wisconsin Card Sort Test: possible interactions with subcortical dopamine.” J Neurosci 14(5 Pt 1):2531-44 Details

    Wilkinson LS, Killcross SS, Humby T, Hall FS, Geyer MA, Robbins TW (1994), “Social isolation in the rat produces developmentally specific deficits in prepulse inhibition of the acoustic startle response without disrupting latent inhibition.” Neuropsychopharmacology 10(1):61-72 Details

    1993

    Burns LH, Robbins TW, Everitt BJ (1993), “Differential effects of excitotoxic lesions of the basolateral amygdala, ventral subiculum and medial prefrontal cortex on responding with conditioned reinforcement and locomotor activity potentiated by intra-accumbens infusions of D-amphetamine.” Behav Brain Res 55(2):167-83 Details

    Gebhard R, Zilles K, Schleicher A, Everitt BJ, Robbins TW, Divac I (1993), “Distribution of seven major neurotransmitter receptors in the striate cortex of the New World monkey Callithrix jacchus.” Neuroscience 56(4):877-85 Details

    Geyer MA, Wilkinson LS, Humby T, Robbins TW (1993), “Isolation rearing of rats produces a deficit in prepulse inhibition of acoustic startle similar to that in schizophrenia.” Biol Psychiatry 34(6):361-72 Details

    Joyce EM, Robbins TW (1993), “Memory deficits in Korsakoff and non-Korsakoff alcoholics following alcohol withdrawal and the relationship to length of abstinence.” Alcohol Alcohol Suppl 2:501-5 Details

    Killcross AS, Robbins TW (1993), “Differential effects of intra-accumbens and systemic amphetamine on latent inhibition using an on-baseline, within-subject conditioned suppression paradigm.” Psychopharmacology (Berl) 110(4):479-89 Details

    Lange KW, Paul GM, Robbins TW, Marsden CD (1993), “L-dopa and frontal cognitive function in Parkinson's disease.” Adv Neurol 60:475-8 Details

    Marston HM, Everitt BJ, Robbins TW (1993), “Comparative effects of excitotoxic lesions of the hippocampus and septum/diagonal band on conditional visual discrimination and spatial learning.” Neuropsychologia 31(10):1099-118 Details

    McAlonan GM, Robbins TW, Everitt BJ (1993), “Effects of medial dorsal thalamic and ventral pallidal lesions on the acquisition of a conditioned place preference: further evidence for the involvement of the ventral striatopallidal system in reward-related processes.” Neuroscience 52(3):605-20 Details

    Muir JL, Page KJ, Sirinathsinghji DJ, Robbins TW, Everitt BJ (1993), “Excitotoxic lesions of basal forebrain cholinergic neurons: effects on learning, memory and attention.” Behav Brain Res 57(2):123-31 Details

    Owen AM, Beksinska M, James M, Leigh PN, Summers BA, Marsden CD, Quinn NP, Sahakian BJ, Robbins TW (1993), “Visuospatial memory deficits at different stages of Parkinson's disease.” Neuropsychologia 31(7):627-44 Details

    Owen AM, Roberts AC, Hodges JR, Summers BA, Polkey CE, Robbins TW (1993), “Contrasting mechanisms of impaired attentional set-shifting in patients with frontal lobe damage or Parkinson's disease.” Brain 116 ( Pt 5):1159-75 Details

    Phillips GD, Le Noury J, Wolterink G, Donselaar-Wolterink I, Robbins TW, Everitt BJ (1993), “Cholecystokinin-dopamine interactions within the nucleus accumbens in the control over behaviour by conditioned reinforcement.” Behav Brain Res 55(2):223-31 Details

    Wilkinson LS, Mittleman G, Torres E, Humby T, Hall FS, Robbins TW (1993), “Enhancement of amphetamine-induced locomotor activity and dopamine release in nucleus accumbens following excitotoxic lesions of the hippocampus.” Behav Brain Res 55(2):143-50 Details

    Wolterink G, Phillips G, Cador M, Donselaar-Wolterink I, Robbins TW, Everitt BJ (1993), “Relative roles of ventral striatal D1 and D2 dopamine receptors in responding with conditioned reinforcement.” Psychopharmacology (Berl) 110(3):355-64 Details

    1992

    Cole BJ, Robbins TW (1992), “Forebrain norepinephrine: role in controlled information processing in the rat.” Neuropsychopharmacology 7(2):129-42 Details

    Czyrak A, Dooley DJ, Jones GH, Robbins TW (1992), “Social isolation increases the density of [125I]omega-conotoxin GVIA binding sites in the rat frontal cortex and caudate nucleus.” Brain Res 583(1-2):189-93 Details

    Dunnett SB, Robbins TW (1992), “The functional role of mesotelencephalic dopamine systems.” Biol Rev Camb Philos Soc 67(4):491-518 Details

    Jones GH, Hernandez TD, Kendall DA, Marsden CA, Robbins TW (1992), “Dopaminergic and serotonergic function following isolation rearing in rats: study of behavioural responses and postmortem and in vivo neurochemistry.” Pharmacol Biochem Behav 43(1):17-35 Details

    Jones GH, Robbins TW (1992), “Differential effects of mesocortical, mesolimbic, and mesostriatal dopamine depletion on spontaneous, conditioned, and drug-induced locomotor activity.” Pharmacol Biochem Behav 43(3):887-95 Details

    Lange KW, Robbins TW, Marsden CD, James M, Owen AM, Paul GM (1992), “L-dopa withdrawal in Parkinson's disease selectively impairs cognitive performance in tests sensitive to frontal lobe dysfunction.” Psychopharmacology (Berl) 107(2-3):394-404 Details

    Marston HM, Garcha HS, Robbins TW, Stolerman IP (1992), “Drug discrimination learning in rats with excitotoxic lesions of nucleus basalis and ventral globus pallidus.” Behav Brain Res 51(1):93-102 Details

    Mayer E, Brown VJ, Dunnett SB, Robbins TW (1992), “Striatal Graft-Associated Recovery of a Lesion-Induced Performance Deficit in the Rat Requires Learning to Use The Transplant.” Eur J Neurosci 4(2):119-126 Details

    Muir JL, Dunnett SB, Robbins TW, Everitt BJ (1992), “Attentional functions of the forebrain cholinergic systems: effects of intraventricular hemicholinium, physostigmine, basal forebrain lesions and intracortical grafts on a multiple-choice serial reaction time task.” Exp Brain Res 89(3):611-22 Details

    Muir JL, Robbins TW, Everitt BJ (1992), “Disruptive effects of muscimol infused into the basal forebrain on conditional discrimination and visual attention: differential interactions with cholinergic mechanisms.” Psychopharmacology (Berl) 107(4):541-50 Details

    Owen AM, James M, Leigh PN, Summers BA, Marsden CD, Quinn NP, Lange KW, Robbins TW (1992), “Fronto-striatal cognitive deficits at different stages of Parkinson's disease.” Brain 115 ( Pt 6):1727-51 Details

    Robbins TW, James M, Lange KW, Owen AM, Quinn NP, Marsden CD (1992), “Cognitive performance in multiple system atrophy.” Brain 115 Pt 1:271-91 Details

    Roberts AC, Robbins TW, Everitt BJ, Muir JL (1992), “A specific form of cognitive rigidity following excitotoxic lesions of the basal forebrain in marmosets.” Neuroscience 47(2):251-64 Details

    1991

    Brown VJ, Bowman EM, Robbins TW (1991), “Response-related deficits following unilateral lesions of the medial agranular cortex of the rat.” Behav Neurosci 105(4):567-78 Details

    Brown VJ, Robbins TW (1991), “Simple and choice reaction time performance following unilateral striatal dopamine depletion in the rat. Impaired motor readiness but preserved response preparation.” Brain 114 ( Pt 1B):513-25 Details

    Cador M, Taylor JR, Robbins TW (1991), “Potentiation of the effects of reward-related stimuli by dopaminergic-dependent mechanisms in the nucleus accumbens.” Psychopharmacology (Berl) 104(3):377-85 Details

    Dunnett SB, Everitt BJ, Robbins TW (1991), “The basal forebrain-cortical cholinergic system: interpreting the functional consequences of excitotoxic lesions.” Trends Neurosci 14(11):494-501 Details

    Everitt BJ, Morris KA, O'Brien A, Robbins TW (1991), “The basolateral amygdala-ventral striatal system and conditioned place preference: further evidence of limbic-striatal interactions underlying reward-related processes.” Neuroscience 42(1):1-18 Details

    Jones GH, Marsden CA, Robbins TW (1991), “Behavioural rigidity and rule-learning deficits following isolation-rearing in the rat: neurochemical correlates.” Behav Brain Res 43(1):35-50 Details

    Joyce EM, Robbins TW (1991), “Frontal lobe function in Korsakoff and non-Korsakoff alcoholics: planning and spatial working memory.” Neuropsychologia 29(8):709-23 Details

    Mittleman G, Jones GH, Robbins TW (1991), “Sensitization of amphetamine-stereotypy reduces plasma corticosterone: implications for stereotypy as a coping response.” Behav Neural Biol 56(2):170-82 Details

    Owen AM, Roberts AC, Polkey CE, Sahakian BJ, Robbins TW (1991), “Extra-dimensional versus intra-dimensional set shifting performance following frontal lobe excisions, temporal lobe excisions or amygdalo-hippocampectomy in man.” Neuropsychologia 29(10):993-1006 Details

    Page KJ, Everitt BJ, Robbins TW, Marston HM, Wilkinson LS (1991), “Dissociable effects on spatial maze and passive avoidance acquisition and retention following AMPA- and ibotenic acid-induced excitotoxic lesions of the basal forebrain in rats: differential dependence on cholinergic neuronal loss.” Neuroscience 43(2-3):457-72 Details

    Reading PJ, Dunnett SB, Robbins TW (1991), “Dissociable roles of the ventral, medial and lateral striatum on the acquisition and performance of a complex visual stimulus-response habit.” Behav Brain Res 45(2):147-61 Details

    Robbins TW (1991), “Subjective drug effects in context Commentary on Preston and Bigelow "Subjective and discriminative effects of drugs"” Behav Pharmacol 2(4 And 5):315-317 Details

    Robbins TW, de Wied D (1991), “Mode of action of apomorphine and dexamphetamine on gnawing compulsion in rats: A.M. Ernst. Psychopharmacologia (Berl.) 10, 316-323 (1967)” Psychopharmacology (Berl) 103(3):285-6 Details

    Selden NR, Everitt BJ, Jarrard LE, Robbins TW (1991), “Complementary roles for the amygdala and hippocampus in aversive conditioning to explicit and contextual cues.” Neuroscience 42(2):335-50 Details

    Selden NR, Everitt BJ, Robbins TW (1991), “Telencephalic but not diencephalic noradrenaline depletion enhances behavioural but not endocrine measures of fear conditioning to contextual stimuli.” Behav Brain Res 43(2):139-54 Details

    1990

    Jones GH, Marsden CA, Robbins TW (1990), “Increased sensitivity to amphetamine and reward-related stimuli following social isolation in rats: possible disruption of dopamine-dependent mechanisms of the nucleus accumbens.” Psychopharmacology (Berl) 102(3):364-72 Details

    Mittleman G, Brener J, Robbins TW (1990), “Physiological correlates of schedule-induced activities in rats.” Am J Physiol 259(3 Pt 2):R485-91 Details

    Mittleman G, Whishaw IQ, Jones GH, Koch M, Robbins TW (1990), “Cortical, hippocampal, and striatal mediation of schedule-induced behaviors.” Behav Neurosci 104(3):399-409 Details

    Owen AM, Downes JJ, Sahakian BJ, Polkey CE, Robbins TW (1990), “Planning and spatial working memory following frontal lobe lesions in man.” Neuropsychologia 28(10):1021-34 Details

    Robbins TW (1990), “The case of frontostriatal dysfunction in schizophrenia.” Schizophr Bull 16(3):391-402 Details

    Robbins TW, Giardini V, Jones GH, Reading P, Sahakian BJ (1990), “Effects of dopamine depletion from the caudate-putamen and nucleus accumbens septi on the acquisition and performance of a conditional discrimination task.” Behav Brain Res 38(3):243-61 Details

    Roberts AC, Robbins TW, Everitt BJ, Jones GH, Sirkia TE, Wilkinson J, Page K (1990), “The effects of excitotoxic lesions of the basal forebrain on the acquisition, retention and serial reversal of visual discriminations in marmosets.” Neuroscience 34(2):311-29 Details

    Sahakian BJ, Downes JJ, Eagger S, Evenden JL, Levy R, Philpot MP, Roberts AC, Robbins TW (1990), “Sparing of attentional relative to mnemonic function in a subgroup of patients with dementia of the Alzheimer type.” Neuropsychologia 28(11):1197-213 Details

    Selden NR, Cole BJ, Everitt BJ, Robbins TW (1990), “Damage to ceruleo-cortical noradrenergic projections impairs locally cued but enhances spatially cued water maze acquisition.” Behav Brain Res 39(1):29-51 Details

    Selden NR, Robbins TW, Everitt BJ (1990), “Enhanced behavioral conditioning to context and impaired behavioral and neuroendocrine responses to conditioned stimuli following ceruleocortical noradrenergic lesions: support for an attentional hypothesis of central noradrenergic function.” J Neurosci 10(2):531-9 Details

    1989

    Annett LE, McGregor A, Robbins TW (1989), “The effects of ibotenic acid lesions of the nucleus accumbens on spatial learning and extinction in the rat.” Behav Brain Res 31(3):231-42 Details

    Brown VJ, Robbins TW (1989), “Elementary processes of response selection mediated by distinct regions of the striatum.” J Neurosci 9(11):3760-5 Details

    Brown VJ, Robbins TW (1989), “Deficits in response space following unilateral striatal dopamine depletion in the rat.” J Neurosci 9(3):983-9 Details

    Cador M, Robbins TW, Everitt BJ (1989), “Involvement of the amygdala in stimulus-reward associations: interaction with the ventral striatum.” Neuroscience 30(1):77-86 Details

    Carli M, Jones GH, Robbins TW (1989), “Effects of unilateral dorsal and ventral striatal dopamine depletion on visual neglect in the rat: a neural and behavioural analysis.” Neuroscience 29(2):309-27 Details

    Cole BJ, Robbins TW (1989), “Effects of 6-hydroxydopamine lesions of the nucleus accumbens septi on performance of a 5-choice serial reaction time task in rats: implications for theories of selective attention and arousal.” Behav Brain Res 33(2):165-79 Details

    Downes JJ, Roberts AC, Sahakian BJ, Evenden JL, Morris RG, Robbins TW (1989), “Impaired extra-dimensional shift performance in medicated and unmedicated Parkinson's disease: evidence for a specific attentional dysfunction.” Neuropsychologia 27(11-12):1329-43 Details

    Evenden JL, Marston HM, Jones GH, Giardini V, Lenard L, Everitt BJ, Robbins TW (1989), “Effects of excitotoxic lesions of the substantia innominata, ventral and dorsal globus pallidus on visual discrimination acquisition, performance and reversal in the rat.” Behav Brain Res 32(2):129-49 Details

    Everitt BJ, Cador M, Robbins TW (1989), “Interactions between the amygdala and ventral striatum in stimulus-reward associations: studies using a second-order schedule of sexual reinforcement.” Neuroscience 30(1):63-75 Details

    Jones GH, Mittleman G, Robbins TW (1989), “Attenuation of amphetamine-stereotypy by mesostriatal dopamine depletion enhances plasma corticosterone: implications for stereotypy as a coping response.” Behav Neural Biol 51(1):80-91 Details

    Jones GH, Robbins TW, Marsden CA (1989), “Isolation-rearing retards the acquisition of schedule-induced polydipsia in rats.” Physiol Behav 45(1):71-7 Details

    Robbins TW, Cador M, Taylor JR, Everitt BJ (1989), “Limbic-striatal interactions in reward-related processes.” Neurosci Biobehav Rev 13(2-3):155-62 Details

    Robbins TW, Everitt BJ, Marston HM, Wilkinson J, Jones GH, Page KJ (1989), “Comparative effects of ibotenic acid- and quisqualic acid-induced lesions of the substantia innominata on attentional function in the rat: further implications for the role of the cholinergic neurons of the nucleus basalis in cognitive processes.” Behav Brain Res 35(3):221-40 Details

    Robbins TW, Everitt BJ, Ryan CN, Marston HM, Jones GH, Page KJ (1989), “Comparative effects of quisqualic and ibotenic acid-induced lesions of the substantia innominata and globus pallidus on the acquisition of a conditional visual discrimination: differential effects on cholinergic mechanisms.” Neuroscience 28(2):337-52 Details

    1988

    Cole BJ, Robbins TW, Everitt BJ (1988), “Lesions of the dorsal noradrenergic bundle simultaneously enhance and reduce responsivity to novelty in a food preference test.” Brain Res 472(4):325-49 Details

    Everitt BJ, Sirkiä TE, Roberts AC, Jones GH, Robbins TW (1988), “Distribution and some projections of cholinergic neurons in the brain of the common marmoset, Callithrix jacchus.” J Comp Neurol 271(4):533-58 Details

    Mittleman G, Jones GH, Robbins TW (1988), “The relationship between schedule-induced polydipsia and pituitary-adrenal activity: pharmacological and behavioral manipulations.” Behav Brain Res 28(3):315-24 Details

    Mittleman G, Jones GH, Robbins TW (1988), “Effects of diazepam, FG 7142, and RO 15-1788 on schedule-induced polydipsia and the temporal control of behavior.” Psychopharmacology (Berl) 94(1):103-9 Details

    Mittleman G, Whishaw IQ, Robbins TW (1988), “Cortical lateralization of function in rats in a visual reaction time task.” Behav Brain Res 31(1):29-36 Details

    Morris RG, Downes JJ, Sahakian BJ, Evenden JL, Heald A, Robbins TW (1988), “Planning and spatial working memory in Parkinson's disease.” J Neurol Neurosurg Psychiatry 51(6):757-66 Details

    Robbins TW (1988), “Alzheimer's disease. Arresting memory decline.” Nature 336(6196):207-8 Details

    Roberts AC, Robbins TW, Everitt BJ (1988), “The effects of intradimensional and extradimensional shifts on visual discrimination learning in humans and non-human primates.” Q J Exp Psychol B 40(4):321-41 Details

    Sahakian BJ, Morris RG, Evenden JL, Heald A, Levy R, Philpot M, Robbins TW (1988), “A comparative study of visuospatial memory and learning in Alzheimer-type dementia and Parkinson's disease.” Brain 111 ( Pt 3):695-718 Details

    1987

    Cole BJ, Robbins TW (1987), “Dissociable effects of lesions to the dorsal or ventral noradrenergic bundle on the acquisition, performance, and extinction of aversive conditioning.” Behav Neurosci 101(4):476-88 Details

    Cole BJ, Robbins TW (1987), “Amphetamine impairs the discriminative performance of rats with dorsal noradrenergic bundle lesions on a 5-choice serial reaction time task: new evidence for central dopaminergic-noradrenergic interactions.” Psychopharmacology (Berl) 91(4):458-66 Details

    Dooley DJ, Jones GH, Robbins TW (1987), “Noradrenaline- and time-dependent changes in neocortical alpha 2- and beta 1-adrenoceptor binding in dorsal noradrenergic bundle-lesioned rats.” Brain Res 420(1):152-6 Details

    Everitt BJ, Robbins TW, Evenden JL, Marston HM, Jones GH, Sirkiä TE (1987), “The effects of excitotoxic lesions of the substantia innominata, ventral and dorsal globus pallidus on the acquisition and retention of a conditional visual discrimination: implications for cholinergic hypotheses of learning and memory.” Neuroscience 22(2):441-69 Details

    Robbins TW, Everitt BJ (1987), “Comparative functions of the central noradrenergic, dopaminergic and cholinergic systems.” Neuropharmacology 26(7B):893-901 Details

    1986

    Mohammed AK, Callenholm NE, Järbe TU, Swedberg MD, Danysz W, Robbins TW, Archer T (1986), “Role of central noradrenaline neurons in the contextual control of latent inhibition in taste aversion learning.” Behav Brain Res 21(2):109-18 Details

    Robbins TW, Evenden JL, Ksir C, Reading P, Wood S, Carli M (1986), “The effects of d-amphetamine, alpha-flupenthixol, and mesolimbic dopamine depletion on a test of attentional switching in the rat.” Psychopharmacology (Berl) 90(1):72-8 Details

    Taylor JR, Robbins TW (1986), “6-Hydroxydopamine lesions of the nucleus accumbens, but not of the caudate nucleus, attenuate enhanced responding with reward-related stimuli produced by intra-accumbens d-amphetamine.” Psychopharmacology (Berl) 90(3):390-7 Details

    1985

    Carli M, Evenden JL, Robbins TW (1985), “Depletion of unilateral striatal dopamine impairs initiation of contralateral actions and not sensory attention.” Nature 313(6004):679-82 Details

    Evenden JL, Robbins TW (1985), “The effects of d-amphetamine, chlordiazepoxide and alpha-flupenthixol on food-reinforced tracking of a visual stimulus by rats.” Psychopharmacology (Berl) 85(3):361-6 Details

    Winn P, Robbins TW (1985), “Comparative effects of infusions of 6-hydroxydopamine into nucleus accumbens and anterolateral hypothalamus induced by 6-hydroxydopamine on the response to dopamine agonists, body weight, locomotor activity and measures of exploration in the rat.” Neuropharmacology 24(1):25-31 Details

    1984

    Evenden JL, Robbins TW (1984), “Effects of unilateral 6-hydroxydopamine lesions of the caudate-putamen on skilled forepaw use in the rat.” Behav Brain Res 14(1):61-8 Details

    Robbins TW (1984), “Cortical noradrenaline, attention and arousal.” Psychol Med 14(1):13-21 Details

    Taylor JR, Robbins TW (1984), “Enhanced behavioural control by conditioned reinforcers following microinjections of d-amphetamine into the nucleus accumbens.” Psychopharmacology (Berl) 84(3):405-12 Details

    1983

    Carli M, Robbins TW, Evenden JL, Everitt BJ (1983), “Effects of lesions to ascending noradrenergic neurones on performance of a 5-choice serial reaction task in rats; implications for theories of dorsal noradrenergic bundle function based on selective attention and arousal.” Behav Brain Res 9(3):361-80 Details

    Evenden JL, Robbins TW (1983), “Increased response switching, perseveration and perseverative switching following d-amphetamine in the rat.” Psychopharmacology (Berl) 80(1):67-73 Details

    Evenden JL, Robbins TW (1983), “Dissociable effects of d-amphetamine, chlordiazepoxide and alpha-flupenthixol on choice and rate measures of reinforcement in the rat.” Psychopharmacology (Berl) 79(2-3):180-6 Details

    Everitt BJ, Robbins TW, Gaskin M, Fray PJ (1983), “The effects of lesions to ascending noradrenergic neurons on discrimination learning and performance in the rat.” Neuroscience 10(2):397-410 Details

    Robbins TW, Roberts DC, Koob GF (1983), “Effects of d-amphetamine and apomorphine upon operant behavior and schedule-induced licking in rats with 6-hydroxydopamine-induced lesions of the nucleus accumbens.” J Pharmacol Exp Ther 224(3):662-73 Details

    Robbins TW, Watson BA, Gaskin M, Ennis C (1983), “Contrasting interactions of pipradrol, d-amphetamine, cocaine, cocaine analogues, apomorphine and other drugs with conditioned reinforcement.” Psychopharmacology (Berl) 80(2):113-9 Details

    Sahakian BJ, Trayhurn P, Wallace M, Deeley R, Winn P, Robbins TW, Everitt BJ (1983), “Increased weight gain and reduced activity in brown adipose tissue produced by depletion of hypothalamic noradrenaline.” Neurosci Lett 39(3):321-6 Details

    Sahakian BJ, Winn P, Robbins TW, Deeley RJ, Everitt BJ, Dunn LT, Wallace M, James WP (1983), “Changes in body weight and food-related behaviour induced by destruction of the ventral or dorsal noradrenergic bundle in the rat.” Neuroscience 10(4):1405-20 Details

    Winn P, Farrell A, Maconick A, Robbins TW (1983), “Behavioral and pharmacological specificity of the feeding elicited by cholinergic stimulation of the substantia nigra in the rat.” Behav Neurosci 97(5):794-809 Details

    1982

    Robbins TW, Everitt BJ (1982), “Functional studies of the central catecholamines.” Int Rev Neurobiol 23:303-65 Details

    1981

    Sahakian BJ, Lean ME, Robbins TW, James WP (1981), “Salivation and insulin secretion in response to food in non-obese men and women.” Appetite 2(3):209-16 Details

    1980

    Fray PJ, Sahakian BJ, Robbins TW, Koob GF, Iversen SD (1980), “An observational method for quantifying the behavioural effects of dopamine agonists: contrasting effects of d-amphetamine and apomorphine.” Psychopharmacology (Berl) 69(3):253-9 Details

    Robbins TW, Koob GF (1980), “Selective disruption of displacement behaviour by lesions of the mesolimbic dopamine system.” Nature 285(5764):409-12 Details

    1979

    Mason ST, Robbins TW (1979), “Noradrenaline and conditioned reinforcement.” Behav Neural Biol 25(4):523-34 Details

    Robbins TW, Sahakian BJ (1979), “"Paradoxical" effects of psychomotor stimulant drugs in hyperactive children from the standpoint of behavioural pharmacology.” Neuropharmacology 18(12):931-50 Details

    1978

    Koob GF, Riley SJ, Smith SC, Robbins TW (1978), “Effects of 6-hydroxydopamine lesions of the nucleus accumbens septi and olfactory tubercle on feeding, locomotor activity, and amphetamine anorexia in the rat.” J Comp Physiol Psychol 92(5):917-27 Details

    Robbins TW (1978), “The acquisition of responding with conditioned reinforcement: effects of pipradrol, methylphenidate, d-amphetamine, and nomifensine.” Psychopharmacology (Berl) 58(1):79-87 Details

    Robbins TW, Koob GF (1978), “Pipradrol enhances reinforcing properties of stimuli paired with brain stimulation.” Pharmacol Biochem Behav 8(3):219-22 Details

    1977

    Robbins TW (1977), “Reward enhancement by psychomotor stimulant drugs [proceedings]” Neuropharmacology 16(7-8):529-30 Details

    Robbins TW, Phillips AG, Sahakian BJ (1977), “Effects of chlordiazepoxide on tail pinch-induced eating in rats.” Pharmacol Biochem Behav 6(3):297-302 Details

    Sahakian BJ, Robbins TW (1977), “Are the effects of psychomotor stimulant drugs on hyperactive children really paradoxical?” Med Hypotheses 3(4):154-8 Details

    Sahakian BJ, Robbins TW (1977), “Isolation-rearing enhances tail pinch-induced oral behavior in rats.” Physiol Behav 18(1):53-8 Details

    1976

    Rapp DL, Robbins TW (1976), “The effects of d-amphetamine on temporal discrimination in the rat.” Psychopharmacology (Berl) 51(1):91-100 Details

    Robbins TW (1976), “Relationship between reward-enhancing and stereotypical effects of psychomotor stimulant drugs.” Nature 264(5581):57-9 Details

    Sahakian BJ, Robbins TW, Iversen SD (1976), “Alpha-flupenthixol-induced hyperactivity by chronic dosing in rats.” Eur J Pharmacol 37(1):169-78 Details

    1975

    Sahakian BJ, Robbins TW (1975), “Potentiation of locomotor activity and modification of sterotypy by starvation in adomorphine treated rats.” Neuropharmacology 14(4):251-7 Details

    Sahakian BJ, Robbins TW, Morgan MJ, Iversen SD (1975), “The effects of psychomotor stimulants on stereotypy and locomotor activity in socially-deprived and control rats.” Brain Res 84(2):195-205 Details

    1973

    Robbins TW, Iversen SD (1973), “Amphetamine-induced disruption of temporal discrimination by response disinhibition.” Nat New Biol 245(145):191-2 Details