Ms Juliet Griffin

Juliet Griffin

University position

PhD student
Supervised by Prof Paul Fletcher

Departments

Department of Psychiatry

Institutes

Behavioural and Clinical Neuroscience Institute and Developmental Psychiatry

Research Theme

Cognitive and Behavioural Neuroscience

Interests

I study the cognitive and neural mechanisms underlying the formation and stubborn persistence of delusions and other psychotic symptoms in psychiatric illnesses like schizophrenia. I am interested in how the brain uses uncertain information (particularly information from social sources) to update and maintain accurate representations of the world (including self and others), and how and why these processes may become systematically derailed in psychotic illness. My PhD research uses computational methods to make sense of behavioural and functional imaging data from healthy, clinically 'at risk', currently psychotic, and chronicially schizophrenic individuals engaged in making perceptual and cognitive inferences under uncertainty. I aim to thereby track how changes in uncertainty-weighting of information develops across the illness course, in computational terms that make sense at both the 'brain' and 'mind' levels, and to sensibly relate these to the progression of symptomaticity.

Research Focus

Keywords

delusions

computational modelling

psychosis

predictive processing

reinforcement learning

Clinical conditions

'At Risk Mental State' (ARMS)

Schizophrenia

Equipment

Behavioural analysis

Computational modelling

Magnetic resonance imaging (MRI)

Collaborators

Cambridge

Dan Davies

Emilio Fernandez-Egea

Paul Fletcher

Haarsma Joost

Graham Murray

Associated News Items