Professor John Hodges

Interests

My work has focused on cognitive aspects of Alzheimer’s disease (FTD) and frontotemporal dementia (FTD). It aims to (i) improve the early diagnosis of the degenerative dementias, (ii) understand the cognitive and behavioural changes which occur in the early stages within the framework of cognitive models; and (iii) define the neuroanatomical and neuropathological bases of these disorders. We use neuropsychological, structural (MRI) and functional (FDG-PET) imaging methods. Since neuropathological examination remains the “gold-standard” for diagnosis we have enrolled a large number of prospectively studied cases with over 150 brain donations. Work involving this collection has produced a series of papers on clinico-pathological correlates in FTD syndromes (with John Xuereb & Glenda Halliday, Sydney Australia), identification of atypical AD presentations and the molecular pathology of FTD (with Maria Spillantini).

Research Focus

Equipment

Brain imaging

Neuropsychological testing