Jeroen Verheyen

Jeroen Verheyen

University position

PhD student
Supervised by Stefano Pluchino

Departments

Department of Clinical Neurosciences

Institutes

Cambridge Centre for Brain Repair

Email

jjyv2@cam.ac.uk

Home page

http://uk.linkedin.com/pub/jer...

Research Theme

Cellular and Molecular Neuroscience

Interests

Nanomedicine and neuroscience have always been great passions of mine. My drive is towards creating nanotherapeutics that enable brain repair and regeneration. Currently, I am working on establishing a highly modular nanotechnology platform for neurodegenerative disorders. More specifically, we are engineering packaging RNA (pRNA) nanoparticles to target cells that enhance progression of neurodegeneration or that prevent neuroregeneration, and to deliver disease-specific therapeutic agents such as siRNA’s. Immune reactions are strongly involved in neurodegeneration and are thus promising targets for modulation. We will try to target and modulate reactive astrocytes in spinal cord injury (SCI), endothelial cells in multiple sclerosis (MS), and dopaminergic cells in Parkinson’s disease (PD), aspiring to reduce the disease progress and regenerate the damaged tissue.

Research Focus

Keywords

Nanotechnology

Nanomedicine

Drug delivery

siRNA

Glia

Clinical conditions

Autoimmune diseases

Cerebrovascular disorders

Multiple sclerosis

Parkinson's disease

Spinal cord injury

Traumatic brain injury

Equipment

Behavioural analysis

Cell culture

Cross-sectional and cohort studies

Fluorescence microscopy

Immunohistochemistry

Protein purification

Collaborators

International

Guo Peixuan Web: http://nanobio.uky.edu/Guo/pei...

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