Professor Colin Taylor

Colin Taylor

University position

Professor

Professor Colin Taylor is pleased to consider applications from prospective PhD students.

Departments

Department of Pharmacology

Email

cwt1000@cam.ac.uk

Home page

http://www.phar.cam.ac.uk/ri/tayl...

Research Theme

Cellular and Molecular Neuroscience

The Cambridge Neuroscience Community

Interests

Roles of inositol trisphosphate (IP3) receptors in generating intracellular calcium signals. Structural determinants of IP3 receptor behaviour. Decoding of calcium signals.

Research Focus

Keywords

calcium

ion channels

IP3 receptor

cell signalling

coding

Clinical conditions

Bipolar disorder

Cerebrovascular disorders

Diabetes

Epilepsy

Hormonal disorders

Huntington's disease

Equipment

Confocal imaging

Electronmicroscopy (EM)

Fluorescence polarization

Förster resonance energy transfer (FRET)

Molecular biology

Single channel recording

Single molecule fluorescence

Collaborators

No collaborators listed

Key publications

Dellis, O, Dedos, SG, Tovey, SC, Rahman, U-T, Dubel, SJ, Taylor CW (2006), “Ca2+ entry through plasma membrane IP3 receptors” Science 313:229-233

Parker, AKT, Gergely, F, Taylor CW (2004), “Targeting of inositol 1,4,5-trisphosphate receptors to the endoplasmic reticulum by multiple signals within their transmembrane domains” J Biol Chem 279:23797-23805

daFonseca, PCA, Morris, SA, Nerou, EP, Taylor, CW & Morris, EP (2003), “Domain organisation of the type 1 inositol 1,4,5-trisphosphate receptor as revealed by single particle analysis” Proc Natl Acad USA 100:2936-3941