Professor Barbara Sahakian
Professor Barbara Sahakian is pleased to consider applications from prospective PhD students.
http://www.psychiatry.cam.ac.uk/pages/p... (personal home page)
My research is aimed at understanding the neural basis of cognitive, emotional and behavioural dysfunction in order to develop more effective pharmacological and psychological treatments. The focus of my lab is on early detection, differential diagnosis and proof of concept studies using cognitive enhancing drugs. This research utilises neuropsychological tests, such as the CANTAB tests, which I co-invented and a focus remains on the development of novel tests. Current study participants include healthy volunteers and patient groups with brain injury, Alzheimer’s disease, attention deficit hyperactivity disorder (ADHD), obsessive compulsive disorder, substance abuse, depression and mania. Techniques used include psychopharmacological, neuropsychological, neuroimaging (fMRI and PET) and genetic ones. Results from recent studies of ecstasy use and cognitive enhancement using methylphenidate, modafinil and atomoxetine have led to an interest in pharmacogenomics and neuroethics.
Attention deficit hyperactivity disorder
Obsessive compulsive disorder
Traumatic brain injury
Magnetic resonance imaging (MRI)
Positron Emission Tomography (PET)
Proof of concept trials
Randomised control trials
Rebecca Elliott Web: http://www.medicine.manchester.ac.uk/staff/1473
Naomi Fineberg Web: http://www.ocdaction.org.uk/ocdacti...
Eileen Joyce Web: http://www.icn.ucl.ac.uk/Staff-L...
Albert Michael Web: http://www.wsh.nhs.uk/Default...
Jonathan Roiser Web: http://www.icn.ucl.ac.uk/Staff-L...
Wayne Drevets Web: http://www.laureateinstitute.org/faculty...
Maura Furey Web: http://intramural.nimh.nih.gov/researc...
J. Leon Kenemans Web: http://www.fss.uu.nl/psn/web...
David Kupfer Web: http://www.upmc.com/Communi...
Mitul Mehta Web: http://rg.kcl.ac.uk/staffpr...
Mary Philips Web: http://www.wpic.pitt.edu/researc...
David Steffens Web: http://crtp.mc.duke.edu/faculty...
Chamberlain SR, Muller U, Blackwell AD, Clark L, Robbins TW, Sahakian BJ (2006), “Neurochemical Modulation of Response Inhibition and Probabilistic Learning in Humans” Science 311(5762):861-863 Details
Turner DC, Robbins TW, Clark L, Aron AR, Dowson J, Sahakian BJ (2003), “Cognitive enhancing effects of modafinil in healthy volunteers” Psychopharmacology 165(3):260-269
Swainson R, Galton CJ, Hodges JR, Michael A, Semple J, Dunn BD, Jefferies MC, Iddon JL, Robbins TW, Sahakian BJ (2001), “Early detection and differential diagnosis of Alzheimer’s disease and depression with neuropsychological tasks” Dementia and Geriatric Cognitive Disorders 12:265-280